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5JP4
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BU of 5jp4 by Molmil
Crystal structure of S. pombe Dcp1 in complex with the decapping enhancer EDC
Descriptor: Uncharacterized protein C18G6.09c, mRNA-decapping enzyme subunit 1
Authors:Wurm, J.P, Sprangers, R.
Deposit date:2016-05-03
Release date:2016-06-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface.
Rna, 22, 2016
7PMM
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BU of 7pmm by Molmil
DEAD-box helicase DbpA in the active conformation bound to a ss/dsRNA junction and ADP/BeF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Wurm, J.P.
Deposit date:2021-09-02
Release date:2022-09-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
7PMQ
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BU of 7pmq by Molmil
DEAD-box helicase DbpA in the active conformation bound to a hairpin loop RNA and ADP/BeF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Wurm, J.P.
Deposit date:2021-09-02
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
7BBB
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BU of 7bbb by Molmil
Solution structure of C-terminal RecA and RRM domains of the DEAD box helicase DbpA
Descriptor: ATP-dependent RNA helicase DbpA
Authors:Wurm, J.P, Sprangers, R.
Deposit date:2020-12-17
Release date:2021-07-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PLI
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BU of 7pli by Molmil
DEAD-box helicase DbpA bound to single stranded RNA and ADP/BeF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Wurm, J.P.
Deposit date:2021-08-31
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
5APG
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BU of 5apg by Molmil
Structure of the SAM-dependent rRNA:acp-transferase Tsr3 from Vulcanisaeta distributa
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TSR3, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium
Authors:Wurm, J.P, Immer, C, Pogoryelov, D, Meyer, B, Koetter, P, Entian, K.-D, Woehnert, J.
Deposit date:2015-09-15
Release date:2016-04-27
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Ribosome Biogenesis Factor Tsr3 is the Aminocarboxypropyl Transferase Responsible for 18S Rrna Hypermodification in Yeast and Humans
Nucleic Acids Res., 44, 2016
5AP8
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BU of 5ap8 by Molmil
Structure of the SAM-dependent rRNA:acp-transferase Tsr3 from S. solfataricus
Descriptor: TSR3
Authors:Wurm, J.P, Immer, C, Pogoryelov, D, Meyer, B, Koetter, P, Entian, K.-D, Woehnert, J.
Deposit date:2015-09-14
Release date:2016-04-27
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Ribosome Biogenesis Factor Tsr3 is the Aminocarboxypropyl Transferase Responsible for 18S Rrna Hypermodification in Yeast and Humans
Nucleic Acids Res., 44, 2016
2LCQ
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BU of 2lcq by Molmil
Solution structure of the endonuclease Nob1 from P.horikoshii
Descriptor: Putative toxin VapC6, ZINC ION
Authors:Veith, T, Martin, R, Wurm, J.P, Weis, B, Duchardt-Ferner, E, Safferthal, C, Hennig, R, Mirus, O, Bohnsack, M.T, Woehnert, J, Schleiff, E.
Deposit date:2011-05-05
Release date:2011-12-14
Last modified:2012-05-09
Method:SOLUTION NMR
Cite:Structural and functional analysis of the archaeal endonuclease Nob1.
Nucleic Acids Res., 40, 2012
7PVM
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BU of 7pvm by Molmil
NMR structure of the C. thermophilum Xrn2 zinc finger
Descriptor: 5'-3' exoribonuclease, ZINC ION
Authors:Overbeck, J.H, Sprangers, R, Wurm, J.P.
Deposit date:2021-10-05
Release date:2022-07-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Observation of conformational changes that underlie the catalytic cycle of Xrn2.
Nat.Chem.Biol., 18, 2022
5N2V
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BU of 5n2v by Molmil
Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Edc1, MAGNESIUM ION, ...
Authors:Holdermann, I, Sprangers, R.
Deposit date:2017-02-08
Release date:2017-05-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7AC8
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BU of 7ac8 by Molmil
Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
Descriptor: GLUTAMINE, Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, ...
Authors:Sung, S, Wilmanns, M.
Deposit date:2020-09-10
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
Nat Commun, 12, 2021
4QVK
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BU of 4qvk by Molmil
Apo-crystal structure of Podospora anserina methyltransferase PaMTH1
Descriptor: 1,2-ETHANEDIOL, PaMTH1 Methyltransferase
Authors:Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
Deposit date:2014-07-15
Release date:2015-05-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
2N0J
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BU of 2n0j by Molmil
Solution NMR Structure of the 27 nucleotide engineered neomycin sensing riboswitch RNA-ribostamycin complex
Descriptor: RIBOSTAMYCIN, RNA_(27-MER)
Authors:Duchardt-Ferner, E, Gottstein-Schmidtke, S.R, Weigand, J.E, Ohlenschlaeger, O.E, Wurm, J, Hammann, C, Suess, B, Woehnert, J.
Deposit date:2015-03-09
Release date:2016-02-03
Method:SOLUTION NMR
Cite:What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch.
Angew.Chem.Int.Ed.Engl., 55, 2016
6TRQ
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BU of 6trq by Molmil
S.c. Scavenger Decapping Enzyme DcpS in complex with the capped RNA dinucleotide m7G-GU
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, L-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHONATE, ...
Authors:Fuchs, A.-L, Neu, A, Sprangers, R.
Deposit date:2019-12-19
Release date:2020-07-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.944 Å)
Cite:Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme.
Proc.Natl.Acad.Sci.USA, 117, 2020
4YMG
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BU of 4ymg by Molmil
Crystal structure of SAM-bound Podospora anserina methyltransferase PaMTH1
Descriptor: MAGNESIUM ION, PHOSPHATE ION, Putative SAM-dependent O-methyltranferase, ...
Authors:Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
Deposit date:2015-03-06
Release date:2015-05-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
4YMH
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BU of 4ymh by Molmil
Crystal structure of SAH-bound Podospora anserina methyltransferase PaMTH1
Descriptor: DI(HYDROXYETHYL)ETHER, Putative SAM-dependent O-methyltranferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
Deposit date:2015-03-06
Release date:2015-05-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.876 Å)
Cite:Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
6GBS
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BU of 6gbs by Molmil
Crystal Structure of the C. themophilum Scavenger Decapping Enzyme DcpS apo form
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Putative mRNA decapping protein
Authors:Fuchs, A.-L, Neu, A, Sprangers, R.
Deposit date:2018-04-16
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme.
Proc.Natl.Acad.Sci.USA, 117, 2020
6HAG
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BU of 6hag by Molmil
The structure of the SAM/SAH-binding riboswitch.
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SAM Riboswitch
Authors:Weickhmann, A.K.
Deposit date:2018-08-07
Release date:2019-01-09
Last modified:2020-01-29
Method:SOLUTION NMR
Cite:The structure of the SAM/SAH-binding riboswitch.
Nucleic Acids Res., 47, 2019
6HTJ
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BU of 6htj by Molmil
Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus
Descriptor: Nucleic-acid-binding protein containing a Zn-ribbon, ZINC ION
Authors:Woehnert, J, Pogoryelov, D, Kaiser, M.
Deposit date:2018-10-04
Release date:2019-10-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus.
Febs Open Bio, 2019
6EWT
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BU of 6ewt by Molmil
Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12B-NDD
Descriptor: NRPS Kj12B-NDD
Authors:Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
Deposit date:2017-11-06
Release date:2018-10-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.
Nat Commun, 9, 2018
6EWV
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BU of 6ewv by Molmil
Solution Structure of Docking Domain Complex of RXP NRPS: Kj12C NDD - Kj12B CDD
Descriptor: NRPS Kj12C-NDD, NRPS Kj12B-CDD
Authors:Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
Deposit date:2017-11-06
Release date:2018-10-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.
Nat Commun, 9, 2018
6EWS
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BU of 6ews by Molmil
Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12A-NDD
Descriptor: NRPS Kj12A-NDD
Authors:Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
Deposit date:2017-11-06
Release date:2018-10-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.
Nat Commun, 9, 2018
6EWU
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BU of 6ewu by Molmil
Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12C-NDD
Descriptor: NRPS Kj12C-NDD
Authors:Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J.
Deposit date:2017-11-06
Release date:2018-10-31
Last modified:2023-06-14
Method:SOLID-STATE NMR
Cite:Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.
Nat Commun, 9, 2018
4I68
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BU of 4i68 by Molmil
Crystal structure of the R444A / R449A double mutant of the HERA RNA helicase RRM domain
Descriptor: CHLORIDE ION, Heat resistant RNA dependent ATPase, ZINC ION
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2012-11-29
Release date:2013-04-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera.
Nucleic Acids Res., 41, 2013
4I67
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BU of 4i67 by Molmil
Crystal structure of the RRM domain of RNA helicase HERA from T. thermophilus in complex with GGGC RNA
Descriptor: 5'-R(P*GP*GP*GP*(RPC))-3', Heat resistant RNA dependent ATPase
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2012-11-29
Release date:2013-04-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera.
Nucleic Acids Res., 41, 2013

 

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