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1YMM
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BU of 1ymm by Molmil
TCR/HLA-DR2b/MBP-peptide complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Hahn, M, Nicholson, M.J, Pyrdol, J, Wucherpfennig, K.W.
Deposit date:2005-01-21
Release date:2005-05-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.
NAT.IMMUNOL., 6, 2005
2BC4
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BU of 2bc4 by Molmil
Crystal structure of HLA-DM
Descriptor: CHLORIDE ION, HLA class II histocompatibility antigen, DM alpha chain, ...
Authors:Nicholson, M.J, Moradi, B, Seth, N.P, Xing, X, Cuny, G.D, Stein, R.L, Wucherpfennig, K.W.
Deposit date:2005-10-18
Release date:2006-05-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Small molecules that enhance the catalytic efficiency of HLA-DM.
J.Immunol., 176, 2006
3PL6
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BU of 3pl6 by Molmil
Structure of Autoimmune TCR Hy.1B11 in complex with HLA-DQ1 and MBP 85-99
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MBP peptide / T-cell receptor beta chain chimera, MHC class II HLA-DQ-alpha chain, ...
Authors:Sethi, D.K, Wucherpfennig, K.W.
Deposit date:2010-11-13
Release date:2010-12-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
J.Exp.Med., 208, 2011
1JK8
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BU of 1jk8 by Molmil
Crystal structure of a human insulin peptide-HLA-DQ8 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ8, insulin B peptide
Authors:Lee, K.H, Wucherpfennig, K.W, Wiley, D.C.
Deposit date:2001-07-11
Release date:2001-08-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.
Nat.Immunol., 2, 2001
2HAC
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BU of 2hac by Molmil
Structure of Zeta-Zeta Transmembrane Dimer
Descriptor: T-cell surface glycoprotein CD3 zeta chain
Authors:Chou, J.J, Wucherpfennig, K.W, Schnell, J.R, Call, M.E.
Deposit date:2006-06-12
Release date:2006-10-31
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor.
Cell(Cambridge,Mass.), 127, 2006
2K4F
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BU of 2k4f by Molmil
Mouse CD3epsilon Cytoplasmic Tail
Descriptor: T-cell surface glycoprotein CD3 epsilon chain
Authors:Xu, C, Call, M.E, Schwieters, C.D, Schnell, J.R, Gagnon, E.E, Wucherpfennig, K.W, Chou, J.J.
Deposit date:2008-06-07
Release date:2008-12-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif.
Cell(Cambridge,Mass.), 135, 2008
2L34
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BU of 2l34 by Molmil
Structure of the DAP12 transmembrane homodimer
Descriptor: TYRO protein tyrosine kinase-binding protein
Authors:Call, M.E, Wucherpfennig, K.W, Chou, J.J.
Deposit date:2010-09-06
Release date:2010-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structural basis for intramembrane assembly of an activating immunoreceptor complex.
Nat.Immunol., 11, 2010
2L35
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BU of 2l35 by Molmil
Structure of the DAP12-NKG2C transmembrane heterotrimer
Descriptor: DAP12-NKG2C_TM, TYRO protein tyrosine kinase-binding protein
Authors:Call, M.E, Wucherpfennig, K.W, Chou, J.J.
Deposit date:2010-09-06
Release date:2010-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structural basis for intramembrane assembly of an activating immunoreceptor complex.
Nat.Immunol., 11, 2010
4FQX
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BU of 4fqx by Molmil
Crystal structure of HLA-DM bound to HLA-DR1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
Authors:Sethi, D.K, Pos, W, Wucherpfennig, K.W.
Deposit date:2012-06-25
Release date:2013-01-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
4GBX
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Crystal structure of an immune complex at pH 6.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
Authors:Sethi, D.K, Pos, W, Wucherpfennig, K.W.
Deposit date:2012-07-28
Release date:2013-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
4GRL
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BU of 4grl by Molmil
Crystal structure of a autoimmune TCR-MHC complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II antigen, ...
Authors:Sethi, D.K, Wucherpfennig, K.W.
Deposit date:2012-08-25
Release date:2013-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop.
Nat Commun, 4, 2013
4MAY
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BU of 4may by Molmil
Crystal structure of an immune complex
Descriptor: HY.1B11 TCR alpha chain, MHC class II HLA-DQ-alpha chain, MHC class II antigen, ...
Authors:Sethi, D.K, Wucherpfennig, K.W.
Deposit date:2013-08-18
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop.
Nat Commun, 4, 2013
1BX2
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BU of 1bx2 by Molmil
CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101,DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HLA-DR2)
Authors:Smith, K.J, Pyrdol, J, Gauthier, L, Wiley, D.C, Wucherpfennig, K.
Deposit date:1998-10-12
Release date:1998-10-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein.
J.Exp.Med., 188, 1998
2IJ0
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BU of 2ij0 by Molmil
Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1
Descriptor: Toxic shock syndrome toxin-1, penultimate affinity-matured variant of hVbeta 2.1, D10
Authors:Moza, B, Varma, A.K, Buonpane, R.A, Zhu, P, Herfst, C.A, Nicholson, M.J, Wilbuer, A.K, Nulifer, S, Wucherpfenning, K.W, McCormick, J.K, Kranz, D.M, Sundberg, E.J.
Deposit date:2006-09-28
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1.
Embo J., 26, 2007
4P2Q
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BU of 4p2q by Molmil
Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5c2 peptide, 5cc7 T-cell receptor alpha chain, ...
Authors:Birnbaum, M.E, Ozkan, E, Garcia, K.C.
Deposit date:2014-03-04
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Cell, 157, 2014
4P2R
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BU of 4p2r by Molmil
Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5c1 peptide, 5cc7 T-cell receptor alpha chain, ...
Authors:Birnbaum, M.E, Ozkan, E, Garcia, K.C.
Deposit date:2014-03-04
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.295 Å)
Cite:Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Cell, 157, 2014
4P2O
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BU of 4p2o by Molmil
Crystal structure of the 2B4 TCR in complex with 2A/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A peptide, 2B4 T-cell receptor alpha chain, ...
Authors:Birnbaum, M.E, Ozkan, E, Garcia, K.C.
Deposit date:2014-03-04
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Cell, 157, 2014
5W1M
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BU of 5w1m by Molmil
MACV GP1 CR1-07 Fab complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ...
Authors:Raymond, D.D, Clark, L.E, Abraham, J.
Deposit date:2017-06-03
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.91 Å)
Cite:Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
5W1G
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BU of 5w1g by Molmil
CR1-07 unliganded Fab
Descriptor: CR1-07 Fab heavy chain, CR1-07 Fab light chain
Authors:Raymond, D.D, Clark, L.E, Abraham, J.
Deposit date:2017-06-03
Release date:2018-05-30
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
5W1K
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BU of 5w1k by Molmil
JUNV GP1 CR1-10 Fab CR1-28 Fab complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-10 Fab heavy chain, ...
Authors:Raymond, D.D, Clark, L.E, Abraham, J.
Deposit date:2017-06-03
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018

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