Author results

2W49
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor:TROPONIN C, SKELETAL MUSCLE, TROPONIN T, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-11-24
Release date:2010-05-05
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4A
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor:MYOSIN REGULATORY LIGHT CHAIN 2, SKELETAL MUSCLE ISOFORM, MYOSIN LIGHT CHAIN 3, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-11-24
Release date:2010-04-14
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4G
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK STRETCH STEP
Descriptor:MYOSIN REGULATORY LIGHT CHAIN 2, SKELETAL MUSCLE ISOFORM, MYOSIN LIGHT CHAIN 3, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-11-25
Release date:2010-08-25
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4H
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK RELEASE STEP
Descriptor:MYOSIN REGULATORY LIGHT CHAIN 2, SKELETAL MUSCLE ISOFORM, MYOSIN LIGHT CHAIN 3, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-11-25
Release date:2010-08-25
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4T
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor:MYOSIN HEAVY CHAIN, STRIATED MUSCLE, MYOSIN REGULATORY LIGHT CHAIN, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-01-19
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4U
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A LENGTH STEP
Descriptor:TROPONIN C, SKELETAL MUSCLE, TROPONIN T, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-08-25
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4V
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK RELEASE STEP
Descriptor:MYOSIN HEAVY CHAIN, STRIATED MUSCLE, MYOSIN REGULATORY LIGHT CHAIN, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-09-15
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4W
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK STRETCH STEP
Descriptor:MYOSIN HEAVY CHAIN, STRIATED MUSCLE, MYOSIN REGULATORY LIGHT CHAIN, ...
Authors:Wu, S., Liu, J., Reedy, M.C., Tregear, R.T., Winkler, H., Franzini-Armstrong, C., Sasaki, H., Lucaveche, C., Goldman, Y.E., Reedy, M.K., Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-08-25
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
3F81
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INTERACTION OF VHR WITH SA3
Descriptor:Dual specificity protein phosphatase 3, 2-(5-methyl-4-oxo-2-thioxo-2,4-dihydro-3H-1lambda~4~,3-thiazol-3-yl)ethanesulfonic acid
Authors:Wu, S., Mutelin, T., Tautz, L.
Deposit date:2008-11-11
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.
J.Med.Chem., 52, 2009
2A2F
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CRYSTAL STRUCTURE OF SEC15 C-TERMINAL DOMAIN
Descriptor:Exocyst complex component Sec15
Authors:Wu, S., Mehta, S.Q., Pichaud, F., Bellen, H.J., Quiocho, F.A.
Deposit date:2005-06-22
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo.
Nat.Struct.Mol.Biol., 12, 2005
3JCT
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CRYO-EM STRUCTURE OF EUKARYOTIC PRE-60S RIBOSOMAL SUBUNITS
Descriptor:60S ribosomal protein L2-A, 60S ribosomal protein L3, 60S ribosomal protein L4-A, ...
Authors:Wu, S., Kumcuoglu, B., Yan, K.G., Brown, H., Zhang, Y.X., Tan, D., Gamalinda, M., Yuan, Y., Li, Z.F., Jakovljevic, J., Ma, C.Y., Lei, J.L., Dong, M.Q., Woolford Jr., J.L., Gao, N.
Deposit date:2016-03-09
Release date:2016-06-01
Last modified:2017-02-01
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016
1NIO
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CRYSTAL STRUCTURE OF BETA-LUFFIN, A RIBOSOME INACTIVATING PROTEIN AT 2.0A RESOLUTION
Descriptor:b-luffin, N-ACETYL-D-GLUCOSAMINE
Authors:Wu, S.
Deposit date:2002-12-24
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of beta-luffin, a ribosome-inactivating protein, at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
4WUY
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CRYSTAL STRUCTURE OF PROTEIN LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH LLY-507, A CELL-ACTIVE, POTENT AND SELECTIVE INHIBITOR
Descriptor:N-lysine methyltransferase SMYD2, 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Nguyen, H., Allali-Hassani, A., Antonysamy, S., Chang, S., Chen, L.H., Curtis, C., Emtage, S., Fan, L., Gheyi, T., Li, F., Liu, S., Martin, J.R., Mendel, D., Olsen, J.B., Pelletier, L., Shatseva, T., Wu, S., Zhang, F.F., Arrowsmith, C.H., Brown, P.J., Campbell, R.M., Garcia, B.A., Barsyte-Lovejoy, D., Mader, M., Vedadi, M.
Deposit date:2014-11-04
Release date:2015-04-08
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
J.Biol.Chem., 290, 2015
1FKN
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STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR
Descriptor:MEMAPSIN 2, inhibitor
Authors:Hong, L., Koelsch, G., Lin, X., Wu, S., Terzyan, S., Ghosh, A., Zhang, X.C., Tang, J.
Deposit date:2000-08-09
Release date:2000-10-09
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.
Science, 290, 2000
1KU9
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X-RAY STRUCTURE OF A METHANOCOCCUS JANNASCHII DNA-BINDING PROTEIN: IMPLICATIONS FOR ANTIBIOTIC RESISTANCE IN STAPHYLOCOCCUS AUREUS
Descriptor:hypothetical protein MJ223
Authors:Ray, S.S., Bonanno, J.B., Chen, H., de Lencastre, H., Wu, S., Tomasz, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-01-21
Release date:2002-12-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus
Proteins, 50, 2002
3J94
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STRUCTURE OF ATP-BOUND N-ETHYLMALEIMIDE SENSITIVE FACTOR DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY
Descriptor:Vesicle-fusing ATPase, ADENOSINE-5'-TRIPHOSPHATE
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J95
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STRUCTURE OF ADP-BOUND N-ETHYLMALEIMIDE SENSITIVE FACTOR DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY
Descriptor:Vesicle-fusing ATPase, ADENOSINE-5'-DIPHOSPHATE
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.601 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J96
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE I)
Descriptor:Vesicle-fusing ATPase, Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, ...
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.601 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J97
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE II)
Descriptor:Vesicle-fusing ATPase, Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, ...
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.804 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J98
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE IIIA)
Descriptor:Vesicle-fusing ATPase, Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, ...
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.405 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J99
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE IIIB)
Descriptor:Vesicle-fusing ATPase, Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, ...
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.201 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
4Y6K
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COMPLEX STRUCTURE OF PRESENILIN HOMOLOGUE PSH BOUND TO AN INHIBITOR
Descriptor:Uncharacterized protein PSH, N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide
Authors:Dang, S., Wu, S., Wang, J., Shi, Y.
Deposit date:2015-02-13
Release date:2015-03-18
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.855 Å)
Cite:Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
Proc.Natl.Acad.Sci.USA, 112, 2015
5IHW
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THE CRYSTAL STRUCTURE OF SDRE FROM STAPHYLOCOCCUS AUREUS
Descriptor:Serine-aspartate repeat-containing protein E
Authors:Zhang, S., Wei, J., Wu, S., Zhang, X., Luo, M., Wang, D.
Deposit date:2016-02-29
Release date:2017-03-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The crystal structure of SdrE from staphylococcus aureus
To Be Published
5VKQ
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STRUCTURE OF A MECHANOTRANSDUCTION ION CHANNEL DROSOPHILA NOMPC IN NANODISC
Descriptor:No mechanoreceptor potential C isoform L, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE
Authors:Jin, P., Bulkley, D., Guo, Y., Zhang, W., Guo, Z., Huynh, W., Wu, S., Meltzer, S., Chen, T., Jan, L.Y., Jan, Y.-N., Cheng, Y.
Deposit date:2017-04-22
Release date:2017-06-28
Last modified:2017-09-20
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017
1H8V
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THE X-RAY CRYSTAL STRUCTURE OF THE TRICHODERMA REESEI FAMILY 12 ENDOGLUCANASE 3, CEL12A, AT 1.9 A RESOLUTION
Descriptor:ENDO-BETA-1,4-GLUCANASE, N-ACETYL-D-GLUCOSAMINE
Authors:Sandgren, M., Shaw, A., Ropp, T.H., Wu, S., Bott, R., Cameron, A.D., Stahlberg, J., Mitchinson, C., Jones, T.A.
Deposit date:2001-02-16
Release date:2001-04-24
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The X-Ray Crystal Structure of the Trichoderma Reesei Family 12 Endoglucanase 3, Cel12A, at 1.9 A Resolution
J.Mol.Biol., 308, 2001