Author results

2WII
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COMPLEMENT C3B IN COMPLEX WITH FACTOR H DOMAINS 1-4
分子名称:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR H, ...
著者Wu, J., Janssen, B.J.C., Gros, P.
登録日2009-05-12
公開日2009-06-09
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
1A94
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STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES
分子名称:PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
著者Wu, J., Adomat, J.M., Ridky, T.W., Louis, J.M., Leis, J., Harrison, R.W., Weber, I.T.
登録日1998-04-16
公開日1999-01-13
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
1BAI
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CRYSTAL STRUCTURE OF ROUS SARCOMA VIRUS PROTEASE IN COMPLEX WITH INHIBITOR
分子名称:PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
著者Wu, J., Adomat, J.M., Ridky, T.W., Louis, J.M., Leis, J., Harrison, R.W., Weber, I.T.
登録日1998-04-17
公開日1999-01-13
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
1SYK
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CRYSTAL STRUCTURE OF E230Q MUTANT OF CAMP-DEPENDENT PROTEIN KINASE REVEALS UNEXPECTED APOENZYME CONFORMATION
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit
著者Wu, J., Yang, J., Madhusudan, N., Xuong, N.H., Ten Eyck, L.F., Taylor, S.S.
登録日2004-04-01
公開日2005-05-17
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.
Protein Sci., 14, 2005
1ZTQ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF MMP-13 COMPLEXED WITH WAY-033
分子名称:Collagenase 3, ZINC ION, CALCIUM ION, ...
著者Wu, J., Rush III, T.S., Hotchandani, R., Du, X., Geck, M., Collins, E., Xu, Z.B., Skotnicki, J., Levin, J.I., Lovering, F.
登録日2005-05-27
公開日2006-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of potent and selective MMP-13 inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
2P6E
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CRYSTAL STRUCTURES OF SACCHAROMYCES CEREVISIAE N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA
分子名称:Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
著者Wu, J., Ding, J.
登録日2007-03-18
公開日2007-06-12
最終更新日2011-11-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6F
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CRYSTAL STRUCTURES OF SACCHAROMYCES CEREVISIAE N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA AND INHIBITORS
分子名称:Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
著者Wu, J., Ding, J.
登録日2007-03-18
公開日2007-06-12
最終更新日2011-11-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6G
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CRYSTAL STRUCTURES OF SACCHAROMYCES CEREVISIAE N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA AND INHIBITORS
分子名称:Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL
著者Wu, J., Ding, J.
登録日2007-03-18
公開日2007-06-12
最終更新日2011-11-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
3D94
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CRYSTAL STRUCTURE OF THE INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR KINASE IN COMPLEX WITH PQIP
分子名称:Insulin-like growth factor 1 receptor beta chain, CALCIUM ION, 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
著者Wu, J., Li, W., Miller, W.T., Hubbard, S.R.
登録日2008-05-26
公開日2008-07-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor
Embo J., 27, 2008
6AHR
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CRYO-EM STRUCTURE OF HUMAN RIBONUCLEASE P
分子名称:H1 RNA, Ribonucleases P/MRP protein subunit POP1, Ribonuclease P protein subunit p38, ...
著者Wu, J., Niu, S., Tan, M., Lan, P., Lei, M.
登録日2018-08-20
公開日2018-12-05
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
6AHU
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CRYO-EM STRUCTURE OF HUMAN RIBONUCLEASE P WITH MATURE TRNA
分子名称:H1 RNA, Ribonucleases P/MRP protein subunit POP1, Ribonuclease P protein subunit p38, ...
著者Wu, J., Niu, S., Tan, M., Lan, P., Lei, M.
登録日2018-08-20
公開日2018-12-05
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
6AHV
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CRYSTAL STRUCTURE OF HUMAN RPP40
分子名称:Ribonuclease P protein subunit p40
著者Wu, J., Niu, S., Tan, M., Lan, P., Lei, M.
登録日2018-08-20
公開日2018-12-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
1EHB
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CRYSTAL STRUCTURE OF RECOMBINANT TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
分子名称:PROTEIN (CYTOCHROME B5), PROTOPORPHYRIN IX CONTAINING FE
著者Wu, J., Gan, J.-H., Xia, Z.-X., Wang, Y.-H., Wang, W.-H., Xue, L.-L., Xie, Y., Huang, Z.-X.
登録日2000-02-20
公開日2000-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant.
Proteins, 40, 2000
1ES1
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CRYSTAL STRUCTURE OF VAL61HIS MUTANT OF TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
分子名称:CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Wu, J., Gan, J.-H., Xia, Z.-X., Wang, Y.-H., Wang, W.-H., Xue, L.-L., Xie, Y., Huang, Z.-X.
登録日2000-04-07
公開日2000-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant.
Proteins, 40, 2000
1M2I
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CRYSTAL STRUCTURE OF E44A/E56A MUTANT OF CYTOCHROME B5
分子名称:cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
著者Wu, J., Wang, Y.-H., Gan, J.-H., Wang, W.-H., Sun, B.-Y., Huang, Z.-X., Xia, Z.-X.
登録日2002-06-24
公開日2003-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Cytochrome b5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome c
Chin.J.Chem., 20, 2002
1M2M
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CRYSTAL STRUCTURE OF E44A/E48A/E56A/D60A MUTANT OF CYTOCHROME B5
分子名称:cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
著者Wu, J., Wang, Y.-H., Gan, J.-H., Wang, W.-H., Sun, B.-Y., Huang, Z.-X., Xia, Z.-X.
登録日2002-06-24
公開日2003-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Cytochrome b5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome c
Chin.J.Chem., 20, 2002
1NE4
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CRYSTAL STRUCTURE OF RP-CAMP BINDING R1A SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
分子名称:cAMP-dependent protein kinase type I-alpha regulatory chain, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL
著者Wu, J., Jones, J.M., Xuong, N.H., Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1NE6
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CRYSTAL STRUCTURE OF SP-CAMP BINDING R1A SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
分子名称:cAMP-dependent protein kinase type I-alpha regulatory chain, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL
著者Wu, J., Jones, J.M., Xuong, N.H., Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1RL3
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CRYSTAL STRUCTURE OF CAMP-FREE R1A SUBUNIT OF PKA
分子名称:cAMP-dependent protein kinase type I-alpha regulatory chain, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL
著者Wu, J., Brown, S., Xuong, N.-H., Taylor, S.S.
登録日2003-11-24
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.
Structure, 12, 2004
1YKS
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CRYSTAL STRUCTURE OF YELLOW FEVER VIRUS NS3 HELICASE
分子名称:Genome polyprotein [contains: Flavivirin protease NS3 catalytic subunit]
著者Wu, J., Bera, A.K., Kuhn, R.J., Smith, J.L.
登録日2005-01-18
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.
J.Virol., 79, 2005
2QVS
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CRYSTAL STRUCTURE OF TYPE IIA HOLOENZYME OF CAMP-DEPENDENT PROTEIN KINASE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, cAMP-dependent protein kinase type II-alpha regulatory subunit
著者Wu, J., Brown, S.H.J., von Daake, S., Taylor, S.S.
登録日2007-08-08
公開日2007-10-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity.
Science, 318, 2007
3BU3
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CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH IRS2 KRLB PEPTIDE
分子名称:insulin receptor subunit beta, Insulin receptor substrate 2
著者Wu, J., Hubbard, S.R.
登録日2007-12-31
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3BU5
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CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH IRS2 KRLB PEPTIDE AND ATP
分子名称:insulin receptor subunit beta, Insulin receptor substrate 2, MAGNESIUM ION, ...
著者Wu, J., Hubbard, S.R.
登録日2007-12-31
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3BU6
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CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH IRS2 KRLB PHOSPHOPEPTIDE
分子名称:insulin receptor subunit beta, Insulin receptor substrate 2
著者Wu, J., Hubbard, S.R.
登録日2007-12-31
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3H0L
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STRUCTURE OF TRNA-DEPENDENT AMIDOTRANSFERASE GATCAB FROM AQUIFEX AEOLICUS
分子名称:Glutamyl-tRNA(Gln) amidotransferase subunit A, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Glutamyl-tRNA(Gln) amidotransferase subunit C, ...
著者Wu, J., Bu, W., Sheppard, K., Kitabatake, M., Soll, D., Smith, J.L.
登録日2009-04-09
公開日2009-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009