Author results

3FCX
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CRYSTAL STRUCTURE OF HUMAN ESTERASE D
Descriptor:S-formylglutathione hydrolase, MAGNESIUM ION, CALCIUM ION
Authors:Wu, D., Li, Y., Song, G., Zhang, D., Shaw, N., Liu, Z.J.
Deposit date:2008-11-24
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of human esterase D: a potential genetic marker of retinoblastoma
Faseb J., 23, 2009
1NM8
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STRUCTURE OF HUMAN CARNITINE ACETYLTRANSFERASE: MOLECULAR BASIS FOR FATTY ACYL TRANSFER
Descriptor:Carnitine O-acetyltransferase
Authors:Wu, D., Govindasamy, L., Lian, W., Gu, Y., Kukar, T., Agbandje-McKenna, M., McKenna, R.
Deposit date:2003-01-09
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Human Carnitine Acetyltransferase. Molecular Basis for Fatty Acyl Transfer
J.Biol.Chem., 278, 2003
2FIK
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STRUCTURE OF A MICROBIAL GLYCOSPHINGOLIPID BOUND TO MOUSE CD1D
Descriptor:T-cell surface glycoprotein CD1d1, B(2)-microglobulin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wu, D., Zajonc, D.M.
Deposit date:2005-12-29
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2PVP
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CRYSTAL STRUCTURE OF D-ALANINE-D-ALANINE LIGASE FROM HELICOBACTER PYLORI
Descriptor:D-alanine-D-alanine ligase
Authors:Wu, D., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-05-10
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori.
Proteins, 72, 2008
2RJG
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE FROM ESCHERICHIA COLI
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-10-15
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
2RJH
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE IN D-CYCLOSERINE-BOUND FORM FROM ESCHERICHIA COLI
Descriptor:Alanine racemase, SULFATE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-10-15
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8T
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT P219A
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8U
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221A
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8V
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221K
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8W
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3HXT
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STRUCTURE OF HUMAN MTHFS
Descriptor:5-formyltetrahydrofolate cyclo-ligase, NICKEL (II) ION, MAGNESIUM ION
Authors:Wu, D., Li, Y., Song, G., Cheng, C., Zhang, R., Joachimiak, A., Shaw, N., Liu, Z.-J.
Deposit date:2009-06-22
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
3HY3
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STRUCTURE OF HUMAN MTHFS WITH 10-FORMYLTETRAHYDROFOLATE
Descriptor:5-formyltetrahydrofolate cyclo-ligase, N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid, NICKEL (II) ION, ...
Authors:Wu, D., Li, Y., Song, G., Cheng, C., Shaw, N., Liu, Z.-J.
Deposit date:2009-06-22
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
3HY4
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STRUCTURE OF HUMAN MTHFS WITH N5-IMINIUM PHOSPHATE
Descriptor:5-formyltetrahydrofolate cyclo-ligase, NICKEL (II) ION, MAGNESIUM ION, ...
Authors:Wu, D., Li, Y., Song, G., Cheng, C., Shaw, N., Liu, Z.-J.
Deposit date:2009-06-22
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
3HY6
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STRUCTURE OF HUMAN MTHFS WITH ADP
Descriptor:5-formyltetrahydrofolate cyclo-ligase, NICKEL (II) ION, MAGNESIUM ION, ...
Authors:Wu, D., Li, Y., Song, G., Cheng, C., Shaw, N., Liu, Z.-J.
Deposit date:2009-06-22
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
4DNU
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CRYSTAL STRUCTURE OF THE W285A MUTANT OF UVB-RESISTANCE PROTEIN UVR8
Descriptor:AT5g63860/MGI19_6
Authors:Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4DNV
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CRYSTAL STRUCTURE OF THE W285F MUTANT OF UVB-RESISTANCE PROTEIN UVR8
Descriptor:AT5g63860/MGI19_6
Authors:Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4DNW
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CRYSTAL STRUCTURE OF UVB-RESISTANCE PROTEIN UVR8
Descriptor:AT5g63860/MGI19_6
Authors:Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Wang, J., Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.773 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4M4X
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STRUCTURE AND DIMERIZATION PROPERTIES OF THE ARYL HYDROCARBON RECEPTOR (AHR) PAS-A DOMAIN
Descriptor:Aryl hydrocarbon receptor
Authors:Wu, D., Potluri, N., Kim, Y., Rastinejad, F.
Deposit date:2013-08-07
Release date:2013-09-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain.
Mol.Cell.Biol., 33, 2013
4YLW
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH NO.33 COMPOUND
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, methyl (2Z)-cyano[3-(3-fluoro-4'-methoxybiphenyl-4-yl)-4-oxo-1,3-thiazolidin-2-ylidene]acetate, ...
Authors:Wu, D., Ouyang, P., Lu, W., Huang, J.
Deposit date:2015-03-06
Release date:2016-03-09
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound
To Be Published
4ZP4
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
Authors:Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
Deposit date:2015-05-07
Release date:2015-08-12
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (2.355 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPH
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH PROFLAVINE
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN
Authors:Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
Deposit date:2015-05-07
Release date:2015-08-12
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPK
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH HRE DNA
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
Deposit date:2015-05-08
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPR
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-1A:ARNT COMPLEX WITH HRE DNA
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 1-alpha, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
Deposit date:2015-05-08
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.902 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZQD
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH THE BENZOXADIAZOLE ANTAGONIST 0X3
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
Authors:Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
Deposit date:2015-05-09
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
5BXJ
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COMPLEX OF THE FK1 DOMAIN MUTANT A19T OF FKBP51 WITH 4-NITROPHENOL
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL
Authors:Wu, D., Tao, X., Chen, Z., Han, J., Jia, W., Li, X., Wang, Z., He, Y.X.
Deposit date:2015-06-09
Release date:2016-05-25
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016