Author results

1NAJ
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HIGH RESOLUTION NMR STRUCTURE OF DNA DODECAMER DETERMINED IN AQUEOUS DILUTE LIQUID CRYSTALLINE PHASE
分子名称:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'
著者Wu, Z., Delaglio, F., Tjandra, N., Zhurkin, V., Bax, A.
登録日2002-11-27
公開日2003-07-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Overall structure and sugar dynamics of a DNA dodecamer from homo- and heteronuclear dipolar couplings and (31)P chemical shift anisotropy.
J.Biomol.Nmr, 26, 2003
1ZWM
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NMR STRUCTURE OF MURINE GAMMA-S CRYSTALLIN
分子名称:Gamma crystallin S
著者Wu, Z., Delaglio, F., Wyatt, K., Wistow, G., Bax, A.
登録日2005-06-03
公開日2005-07-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of (gamma)S-crystallin by molecular fragment replacement NMR.
Protein Sci., 14, 2005
1ZWO
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NMR STRUCTURE OF MURINE GAMMA-S CRYSTALLIN
分子名称:Gamma crystallin S
著者Wu, Z., Delaglio, F., Wyatt, K., Wistow, G., Bax, A.
登録日2005-06-04
公開日2005-07-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of (gamma)S-crystallin by molecular fragment replacement NMR.
Protein Sci., 14, 2005
2NRF
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CRYSTAL STRUCTURE OF GLPG, A RHOMBOID FAMILY INTRAMEMBRANE PROTEASE
分子名称:Protein GlpG
著者Wu, Z., Yan, N., Feng, L., Yan, H., Gu, L., Shi, Y.
登録日2006-11-02
公開日2006-11-14
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Nat.Struct.Mol.Biol., 13, 2006
3K2S
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SOLUTION STRUCTURE OF DOUBLE SUPER HELIX MODEL
分子名称:Apolipoprotein A-I, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL
著者Wu, Z., Gogonea, V., Lee, X., Wagner, M.A., Li, X.-M., Huang, Y., Undurti, A., May, R.P., Haertlein, M., Moulin, M., Gutsche, I., Zaccai, G., Didonato, J.A., Hazen, L.S.
登録日2009-09-30
公開日2010-04-07
最終更新日2012-03-21
実験手法SOLUTION SCATTERING
主引用文献Double superhelix model of high density lipoprotein.
J.Biol.Chem., 284, 2009
3GW5
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CRYSTAL STRUCTURE OF HUMAN RENIN COMPLEXED WITH A NOVEL INHIBITOR
分子名称:Renin, (3R)-3-[(1S)-1-(3-chlorophenyl)-1-hydroxy-5-methoxypentyl]-N-{(1S)-2-cyclohexyl-1-[(methylamino)methyl]ethyl}piperidine-1-carboxamide, N-ACETYL-D-GLUCOSAMINE, ...
著者Wu, Z., McKeever, B.M.
登録日2009-03-31
公開日2009-06-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design and optimization of renin inhibitors: Orally bioavailable alkyl amines.
Bioorg.Med.Chem.Lett., 19, 2009
3KM4
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OPTIMIZATION OF ORALLY BIOAVAILABLE ALKYL AMINE RENIN INHIBITORS
分子名称:Renin, N-ACETYL-D-GLUCOSAMINE, (3R)-3-[(1S)-4-(acetylamino)-1-(3-chlorophenyl)-1-hydroxybutyl]-N-{(1S)-2-cyclohexyl-1-[(methylamino)methyl]ethyl}piperidine-1-carboxamide
著者Wu, Z., McKeever, B.M.
登録日2009-11-09
公開日2010-01-12
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Optimization of orally bioavailable alkyl amine renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3Q3T
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ALKYL AMINE RENIN INHIBITORS: FILLING S1 FROM S3
分子名称:Renin, [(1S,3R,4S)-3-amino-4-hydroxycyclopentyl]{(3R)-3-[(1S)-1-(biphenyl-2-yl)-1-hydroxy-5-methoxypentyl]piperidin-1-yl}methanone, N-ACETYL-D-GLUCOSAMINE, ...
著者Wu, Z., McKeever, B.
登録日2010-12-22
公開日2011-08-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket.
Bioorg.Med.Chem.Lett., 21, 2011
3Q4B
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CLINICALLY USEFUL ALKYL AMINE RENIN INHIBITORS
分子名称:Renin, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
著者Wu, Z., McKeever, B.M.
登録日2010-12-23
公開日2011-11-30
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.
ACS Med Chem Lett, 2, 2011
3Q5H
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CLINICALLY USEFUL ALKYL AMINE RENIN INHIBITORS
分子名称:Renin, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
著者Wu, Z., McKeever, B.M.
登録日2010-12-28
公開日2011-11-30
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.
ACS Med Chem Lett, 2, 2011
1YOP
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THE SOLUTION STRUCTURE OF KTI11P
分子名称:Kti11p, ZINC ION
著者Sun, J., Zhang, J., Wu, F., Xu, C., Li, S., Zhao, W., Wu, Z., Wu, J., Zhou, C.-Z., Shi, Y.
登録日2005-01-28
公開日2005-04-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Biochemistry, 44, 2005
1ZXT
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CRYSTAL STRUCTURE OF A VIRAL CHEMOKINE
分子名称:functional macrophage inflammatory protein 1-alpha homolog
著者Luz, J.G., Yu, M., Su, Y., Wu, Z., Zhou, Z., Sun, R., Wilson, I.A.
登録日2005-06-08
公開日2005-08-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
3B4R
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SITE-2 PROTEASE FROM METHANOCALDOCOCCUS JANNASCHII
分子名称:Putative zinc metalloprotease MJ0392, ZINC ION
著者Jeffrey, P.D., Feng, L., Yan, H., Wu, Z., Yan, N., Wang, Z., Shi, Y.
登録日2007-10-24
公開日2008-01-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a site-2 protease family intramembrane metalloprotease.
Science, 318, 2007
5B7W
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CRYSTAL STRUCTURE OF THE YAJQ-FAMILY PROTEIN XC_3703 FROM XANTHOMONAS CAMPESTRIS PV.CAMPESTRIS
分子名称:UPF0234 protein XC_3703
著者Zhao, Z., Wu, Z.
登録日2016-06-10
公開日2016-09-07
最終更新日2016-09-21
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal structure of the YajQ-family protein XC_3703 from Xanthomonas campestris pv. campestris
Acta Crystallogr.,Sect.F, 72, 2016
5VTO
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SOLUTION STRUCTURE OF BLSM
分子名称:Blasticidin M
著者Kang, M., Doddapaneni, K., Heppner, Z., Wu, Z.
登録日2017-05-17
公開日2018-05-23
最終更新日2019-04-24
実験手法SOLUTION NMR
主引用文献Solution Structure of the NUCLEOTIDE hydrolase BlsM: Implication of its Substrate Specificity
To Be Published
1QBQ
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STRUCTURE OF RAT FARNESYL PROTEIN TRANSFERASE COMPLEXED WITH A CVIM PEPTIDE AND ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID.
分子名称:FPT ALPHA-SUBUNIT, FPT BETA-SUBUNIT, ACETYL-CYS-VAL-ILE-SELENOMET-COOH PEPTIDE, ...
著者Strickland, C.L., Windsor, W.T., Syto, R., Wang, L., Bond, R., Wu, Z., Schwartz, J., Le, H.V., Beese, L.S., Weber, P.C.
登録日1999-04-27
公開日1999-06-18
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue
Biochemistry, 37, 1998
5YZ0
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CRYO-EM STRUCTURE OF HUMAN ATR-ATRIP COMPLEX
分子名称:Serine/threonine-protein kinase ATR, ATR-interacting protein
著者Rao, Q., Liu, M., Tian, Y., Wu, Z., Wang, H., Wang, J., Xu, Y.
登録日2017-12-11
公開日2018-01-31
最終更新日2018-03-21
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structure of human ATR-ATRIP complex.
Cell Res., 28, 2018
1K6U
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CRYSTAL STRUCTURE OF CYCLIC BOVINE PANCREATIC TRYPSIN INHIBITOR
分子名称:PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, 1,2-ETHANEDIOL
著者Botos, I., Wu, Z., Lu, W., Wlodawer, A.
登録日2001-10-17
公開日2001-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor.
FEBS Lett., 509, 2001
1N8X
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SOLUTION STRUCTURE OF HIV-1 STEM LOOP SL1
分子名称:HIV-1 STEM LOOP SL1 MONOMERIC RNA
著者Lawrence, D.C., Stover, C.C., Noznitsky, J., Wu, Z., Summers, M.F.
登録日2002-11-21
公開日2003-04-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the Intact Stem and Bulge of HIV-1 Psi-RNA Stem-Loop SL1
J.Mol.Biol., 326, 2003
2KHZ
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SOLUTION STRUCTURE OF RCL
分子名称:c-Myc-responsive protein Rcl
著者Doddapaneni, K., Mahler, B., Yuan, C., Wu, Z.
登録日2009-04-15
公開日2009-10-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of RCL, a novel 2'-deoxyribonucleoside 5'-monophosphate N-glycosidase
J.Mol.Biol., 394, 2009
2KMK
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GFI-1 ZINC FINGERS 3-5 COMPLEXED WITH DNA
分子名称:Zinc finger protein Gfi-1, DNA (5'-D(*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP*TP*GP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*AP*GP*TP*GP*AP*TP*TP*TP*AP*TP*G)-3'), ...
著者Lee, S., Wu, Z.
登録日2009-07-30
公開日2010-03-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of Gfi-1 zinc domain bound to consensus DNA.
J.Mol.Biol., 397, 2010
2M3C
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SOLUTION STRUCTURE OF GAMMAM7-CRYSTALLIN
分子名称:Crystallin, gamma M7
著者Mahler, B., Wu, Z.
登録日2013-01-16
公開日2013-08-28
最終更新日2013-12-25
実験手法SOLUTION NMR
主引用文献Structure and Dynamics of the Fish Eye Lens Protein, gamma M7-Crystallin.
Biochemistry, 52, 2013
2OZ7
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CRYSTAL STRUCTURE OF THE HUMAN ANDROGEN RECEPTOR T877A MUTANT LIGAND-BINDING DOMAIN WITH CYPROTERONE ACETATE
分子名称:Androgen receptor, CYPROTERONE ACETATE
著者Bohl, C.E., Wu, Z., Miller, D.D., Bell, C.E., Dalton, J.T.
登録日2007-02-25
公開日2007-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design.
J.Biol.Chem., 282, 2007
3IR1
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CRYSTAL STRUCTURE OF LIPOPROTEIN GNA1946 FROM NEISSERIA MENINGITIDIS
分子名称:Outer membrane lipoprotein GNA1946, METHIONINE, SULFATE ION
著者Yang, X., Wu, Z., Wang, X., Shen, Y.
登録日2009-08-21
公開日2009-10-13
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis
J.Struct.Biol., 168, 2009
3QZQ
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71D IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (1.7001 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011