Author results

4JCL
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CRYSTAL STRUCTURE OF ALPHA-CGT FROM PAENIBACILLUS MACERANS AT 1.7 ANGSTROM RESOLUTION
Descriptor:Cyclomaltodextrin glucanotransferase, CALCIUM ION, CHLORIDE ION, ...
Authors:Wu, L., Zhou, J., Wu, J., Li, J., Chen, J.
Deposit date:2013-02-22
Release date:2014-02-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Alpha-Cgt from Paenibacillus Macerans at 1.7 Angstrom Resolution
To be Published
4JCM
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CRYSTAL STRUCTURE OF GAMMA-CGTASE FROM ALKALOPHILIC BACILLUS CLARKII AT 1.65 ANGSTROM RESOLUTION
Descriptor:Cyclodextrin glucanotransferase, CALCIUM ION, CHLORIDE ION, ...
Authors:Wu, L., Yang, D., Zhou, J., Wu, J., Chen, J.
Deposit date:2013-02-22
Release date:2014-02-26
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Crystal Structure of Gamma-Cgtase from Alkalophilic Bacillus Clarkii at 1.65 Angstrom Resolution.
To be Published
3PVL
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STRUCTURE OF MYOSIN VIIA MYTH4-FERM-SH3 IN COMPLEX WITH THE CEN1 OF SANS
Descriptor:Myosin VIIa isoform 1, Usher syndrome type-1G protein, GLYCEROL, ...
Authors:Wu, L., Pan, L.F., Wei, Z.Y., Zhang, M.J.
Deposit date:2010-12-07
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
5CF1
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CRYSTAL STRUCTURE OF THE M32V/M78V/I80V/L114F MUTANT OF LEH
Descriptor:Limonene-1,2-epoxide hydrolase
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-08
Release date:2016-07-13
Method:X-RAY DIFFRACTION (2.242 Å)
Cite:Crystal Structure of the M32V/M78V/I80V/L114F mutant of LEH
To Be Published
5CF2
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CRYSTAL STRUCTURE OF THE I80Y/L114V/I116V MUTANT OF LEH
Descriptor:Limonene-1,2-epoxide hydrolase
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-08
Release date:2016-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the I80Y/L114V/I116V mutant of LEH
To Be Published
5CK6
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CRYSTAL STRUCTURE OF SZ348 IN COMPLEX WITH CYCLOPENTENE OXIDE
Descriptor:Limonene-1,2-epoxide hydrolase, (1R,5S)-6-oxabicyclo[3.1.0]hexane, POTASSIUM ION, ...
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-15
Release date:2016-07-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of SZ348 in complex with cyclopentene oxide
To Be Published
5CLK
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CRYSTAL STRUCTURE OF SZ348 IN COMPLEX WITH S,S-CYCLOHEXANEDIOL
Descriptor:Limonene-1,2-epoxide hydrolase, NICKEL (II) ION, (1S,2S)-cyclohexane-1,2-diol, ...
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-16
Release date:2016-07-20
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of SZ348 in complex with S,S-cyclohexanediol
To Be Published
5D74
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THE CRYSTAL STRUCTURE OF LY7917
Descriptor:Putative phage lysin, CHLORIDE ION, SODIUM ION
Authors:Wu, L., Ji, W.H., Sun, J.H., Zhou, J.H.
Deposit date:2015-08-13
Release date:2016-08-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of Ly7917
To Be Published
5D76
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THE CRYSTAL STRUCTURE OF LY7917 WITH THE HYDROLYZING PRODUCT OF MDP
Descriptor:Putative phage lysin, CHLORIDE ION, L-alanyl-D-alpha-glutamine
Authors:Wu, L., Ji, W.H., Sun, J.H., Zhou, J.H.
Deposit date:2015-08-13
Release date:2016-08-17
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The crystal structure of Ly7917
To Be Published
5E8M
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CRYSTAL STRUCTURE OF HUMAN HEPARANASE
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Wu, L., Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E97
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GLYCOSIDE HYDROLASE LIGAND STRUCTURE 1
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Wu, L., Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E98
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CRYSTAL STRUCTURE OF HUMAN HEPARANASE IN COMPLEX WITH HEPMER M04S02A
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Wu, L., Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E9B
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CRYSTAL STRUCTURE OF HUMAN HEPARANASE IN COMPLEX WITH HEPMER M09S05A
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Wu, L., Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E9C
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CRYSTAL STRUCTURE OF HUMAN HEPARANASE IN COMPLEX WITH HEPARIN TETRASACCHARIDE DP4
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Wu, L., Davies, G.J.
Deposit date:2015-10-15
Release date:2015-11-18
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5GKW
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CRYSTAL STRUCTURE OF SZ529 COMPLEX WITH (R,R)-CYCLOPENTANEDIOL
Descriptor:Limonene-1,2-epoxide hydrolase, (1~{R},2~{R})-cyclopentane-1,2-diol
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2016-07-07
Release date:2017-07-12
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:crystal structure of SZ529 complex with (R,R)-cyclopentanediol
To Be Published
5L9Y
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CRYSTAL STRUCTURE OF HUMAN HEPARANASE, IN COMPLEX WITH GLUCURONIC ACID CONFIGURED AZIRIDINE PROBE JJB355
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Wu, L., Jin, Y., Davies, G.J.
Deposit date:2016-06-13
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5L9Z
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CRYSTAL STRUCTURE OF HUMAN HEPARANASE NUCLEOPHILE MUTANT (E343Q), IN COMPLEX WITH UNREACTED GLUCURONIC ACID CONFIGURED AZIRIDINE PROBE JJB355
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, 1,2-ETHANEDIOL, ...
Authors:Wu, L., Jin, Y., Davies, G.J.
Deposit date:2016-06-13
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5LA4
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CRYSTAL STRUCTURE OF APO HUMAN PROHEPARANASE
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Wu, L., Jin, Y., Davies, G.J.
Deposit date:2016-06-13
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5LA7
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CRYSTAL STRUCTURE OF HUMAN PROHEPARANASE, IN COMPLEX WITH GLUCURONIC ACID CONFIGURED AZIRIDINE PROBE JJB355
Descriptor:Heparanase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Wu, L., Jin, Y., Davies, G.J.
Deposit date:2016-06-13
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
6GDT
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CRYSTAL STRUCTURE OF EXO-GLUCOSIDASE/GLUCOSAMINIDASE VC0615 FROM VIBRIO CHOLERAE
Descriptor:Endoglucanase-related protein, 1,2-ETHANEDIOL
Authors:Wu, L., Davies, G.J.
Deposit date:2018-04-24
Release date:2018-08-15
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structure of the GH9 glucosidase/glucosaminidase from Vibrio cholerae.
Acta Crystallogr F Struct Biol Commun, 74, 2018
2L7T
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SOLUTION STRUCTURE OF THE MFS-BOUND SANS CEN2 PEPTIDE
Descriptor:MFS-bound Sans CEN2 peptide
Authors:Pan, L., Wu, L., Wei, Z., Zhang, M.
Deposit date:2010-12-22
Release date:2011-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
2LSR
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SOLUTION STRUCTURE OF HARMONIN N TERMINAL DOMAIN IN COMPLEX WITH A EXON68 ENCODED PEPTIDE OF CADHERIN23
Descriptor:Harmonin, peptide from Cadherin-23
Authors:Pan, L., Wu, L., Zhang, C., Zhang, M.
Deposit date:2012-05-04
Release date:2012-08-15
Method:SOLUTION NMR
Cite:Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia
J.Biol.Chem., 2012
4FHZ
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CRYSTAL STRUCTURE OF A CARBOXYL ESTERASE AT 2.0 ANGSTROM RESOLUTION
Descriptor:Phospholipase/Carboxylesterase, SODIUM ION, DI(HYDROXYETHYL)ETHER
Authors:Wu, L., Ma, J., Zhou, J., Yu, H.
Deposit date:2012-06-07
Release date:2012-10-03
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
4FTW
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CRYSTAL STRUCTURE OF A CARBOXYL ESTERASE N110C/L145H AT 2.3 ANGSTROM RESOLUTION
Descriptor:Phospholipase/Carboxylesterase, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, ...
Authors:Wu, L., Ma, J., Zhou, J., Yu, H.
Deposit date:2012-06-28
Release date:2012-10-03
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
5NPB
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CRYSTAL STRUCTURE OF CJAGD31B (ALPHA-TRANSGLUCOSYLASE FROM GLYCOSIDE HYDROLASE FAMILY 31) IN COMPLEX WITH ALPHA CYCLOPHELLITOL CYCLOSULFATE PROBE ME647
Descriptor:Oligosaccharide 4-alpha-D-glucosyltransferase, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Wu, L., Davies, G.J.
Deposit date:2017-04-16
Release date:2017-08-09
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.
ACS Cent Sci, 3, 2017