Author results

2OSG
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SOLUTION STRUCTURE AND BINDING PROPERTY OF THE DOMAIN-SWAPPED DIMER OF ZO2PDZ2
Descriptor:Tight junction protein ZO-2
Authors:Wu, J.W., Yang, Y.S., Zhang, J.H., Ji, P., Wu, J.H., Shi, Y.Y.
Deposit date:2007-02-05
Release date:2007-09-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins
J.Biol.Chem., 282, 2007
1JD4
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CRYSTAL STRUCTURE OF DIAP1-BIR2
Descriptor:APOPTOSIS 1 INHIBITOR, ZINC ION
Authors:Wu, J.W., Cocina, A.E., Chai, J., Hay, B.A., Shi, Y.
Deposit date:2001-06-12
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides.
Mol.Cell, 8, 2001
1JD5
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CRYSTAL STRUCTURE OF DIAP1-BIR2/GRIM
Descriptor:APOPTOSIS 1 INHIBITOR, cell death protein GRIM, ZINC ION
Authors:Wu, J.W., Cocina, A.E., Chai, J., Hay, B.A., Shi, Y.
Deposit date:2001-06-12
Release date:2001-12-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides.
Mol.Cell, 8, 2001
1JD6
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CRYSTAL STRUCTURE OF DIAP1-BIR2/HID COMPLEX
Descriptor:APOPTOSIS 1 INHIBITOR, head involution defective protein, ZINC ION
Authors:Wu, J.W., Cocina, A.E., Chai, J., Hay, B.A., Shi, Y.
Deposit date:2001-06-12
Release date:2001-12-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides.
Mol.Cell, 8, 2001
3GMJ
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CRYSTAL STRUCTURE OF MAD MH2 DOMAIN
Descriptor:Protein mothers against dpp
Authors:Wu, J.W., Wang, C.
Deposit date:2009-03-14
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the MH2 domain of Drosophila Mad
SCI.CHINA, SER.C: LIFE SCI., 52, 2009
3PZ7
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CRYSTAL STRUCTURE OF CCD1-DIX DOMAIN
Descriptor:Dixin, 1,2-ETHANEDIOL
Authors:Liu, Y.T., Wang, J.W., Chen, L., Wu, J.W.
Deposit date:2010-12-14
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.441 Å)
Cite:Molecular basis of WNT Activation via the DIX-domain protein CCD1
To be Published
2JWE
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SOLUTION STRUCTURE OF THE SECOND PDZ DOMAIN FROM HUMAN ZONULA OCCLUDENS-1: A DIMERIC FORM WITH 3D DOMAIN SWAPPING
Descriptor:Tight junction protein ZO-1
Authors:Ji, P., Wu, J.W., Zhang, J.H., Yang, Y.S., Wu, J.H., Shi, Y.Y.
Deposit date:2007-10-10
Release date:2007-10-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the second PDZ domain of Zonula Occludens 1
Proteins, 79, 2011
4YNZ
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STRUCTURE OF THE N-TERMINAL DOMAIN OF SAD
Descriptor:Serine/threonine-protein kinase BRSK2
Authors:Wu, J.X., Wang, J., Chen, L., Wang, Z.X., Wu, J.W.
Deposit date:2015-03-11
Release date:2015-12-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into the mechanism of synergistic autoinhibition of SAD kinases
Nat Commun, 6, 2015
4YOM
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STRUCTURE OF SAD KINASE
Descriptor:Serine/threonine-protein kinase BRSK2, 1,2-ETHANEDIOL
Authors:Wu, J.X., Wang, J., Chen, L., Wang, Z.X., Wu, J.W.
Deposit date:2015-03-12
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural insight into the mechanism of synergistic autoinhibition of SAD kinases
Nat Commun, 6, 2015
5IRI
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STRUCTURE OF THE MOUSE SAD-B AIS-KA1 FRAGMENT
Descriptor:Serine/threonine-protein kinase BRSK1
Authors:Ma, H., Wu, J.X., Wang, J., Wu, J.W.
Deposit date:2016-03-13
Release date:2016-06-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and inhibition analysis of the mouse SAD-B C-terminal fragment
Biosci.Biotechnol.Biochem., 2016
5YYS
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CRYO-EM STRUCTURE OF L-FUCOKINASE, GDP-FUCOSE PYROPHOSPHORYLASE (FKP)IN BACTEROIDES FRAGILIS
Descriptor:L-fucokinase, L-fucose-1-P guanylyltransferase
Authors:Wang, J., Hu, H., Liu, Y., Zhou, Q., Wu, P., Yan, N., Wang, H.W., Wu, J.W., Sun, L.
Deposit date:2017-12-11
Release date:2018-12-12
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of L-fucokinase/GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis.
Protein Cell, 10, 2019
3PZ8
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CRYSTAL STRUCTURE OF DVL1-DIX(Y17D) MUTANT
Descriptor:Segment polarity protein dishevelled homolog DVL-1
Authors:Dan, Q.J., Chen, L., Zhang, Y.Y., Liu, Y.T., Wu, J.W.
Deposit date:2010-12-14
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.873 Å)
Cite:Molecular basis of WNT activation via the DIX-domain protein CCD1
To be Published
5ZM8
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CRYSTAL STRUCTURE OF ORP2-ORD IN COMPLEX WITH PI(4,5)P2
Descriptor:Oxysterol-binding protein-related protein 2, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate
Authors:Wang, H., Dong, J.Q., Wang, J., Wu, J.W.
Deposit date:2018-04-01
Release date:2019-01-02
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).
Mol. Cell, 73, 2019
1LCY
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CRYSTAL STRUCTURE OF THE MITOCHONDRIAL SERINE PROTEASE HTRA2
Descriptor:HtrA2 serine protease
Authors:Li, W., Srinivasula, S.M., Chai, J., Li, P., Wu, J.W., Zhang, Z., Alnemri, E.S., Shi, Y.
Deposit date:2002-04-07
Release date:2002-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi.
Nat.Struct.Biol., 9, 2002
1SDZ
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CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A REAPER PEPTIDE
Descriptor:Apoptosis 1 inhibitor, Reaper, ZINC ION
Authors:Yan, N., Wu, J.W., Shi, Y.
Deposit date:2004-02-15
Release date:2004-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
1SE0
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CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A GRIM PEPTIDE
Descriptor:Apoptosis 1 inhibitor, Cell death protein Grim, ZINC ION
Authors:Yan, N., Wu, J.W., Shi, Y.
Deposit date:2004-02-15
Release date:2004-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
3DIT
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CRYSTAL STRUCTURE OF MAD MH2 DOMAIN
Descriptor:Protein mothers against dpp
Authors:Hao, R., Wu, J.W., Wang, Z.X.
Deposit date:2008-06-20
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Drosophila Mad MH2 domain.
Acta Crystallogr.,Sect.F, 64, 2008
3PY3
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CRYSTAL STRUCTURE OF PHOSPHORYLATED P38ALPHA MAP KINASE
Descriptor:Mitogen-activated protein kinase 14
Authors:Zhang, Y.Y., Wu, J.W., Wang, Z.X.
Deposit date:2010-12-11
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38{alpha}.
J.Biol.Chem., 286, 2011
3Q47
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CRYSTAL STRUCTURE OF TPR DOMAIN OF CHIP COMPLEXED WITH PSEUDOPHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH HSP70-C PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Hsp70-C peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.543 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q4A
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH PHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.542 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3TG1
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CRYSTAL STRUCTURE OF P38ALPHA IN COMPLEX WITH A MAPK DOCKING PARTNER
Descriptor:Mitogen-activated protein kinase 14, Dual specificity protein phosphatase 10
Authors:Zhang, Y.Y., Wu, J.W., Wang, Z.X.
Deposit date:2011-08-17
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38alpha with the MAPK Binding Domain of the Phosphatase MKP5.
Sci.Signal., 4, 2011
3TG3
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CRYSTAL STRUCTURE OF THE MAPK BINDING DOMAIN OF MKP7
Descriptor:Dual specificity protein phosphatase 16, 1,2-ETHANEDIOL
Authors:Zhang, Y.Y., Liu, X., Wu, J.W., Wang, Z.X.
Deposit date:2011-08-17
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.675 Å)
Cite:A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38alpha with the MAPK Binding Domain of the Phosphatase MKP5.
Sci.Signal., 4, 2011
4F2L
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STRUCTURE OF A REGULATORY DOMAIN OF AMPK
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, MAGNESIUM ION
Authors:Xin, F.J., Zhang, Y.Y., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2012-05-08
Release date:2013-06-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conserved regulatory elements in AMPK
Nature, 498, 2013
4IXP
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CRYSTAL STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (MELK)
Descriptor:Maternal embryonic leucine zipper kinase
Authors:Cao, L.S., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2013-01-27
Release date:2013-09-11
Method:X-RAY DIFFRACTION (2.749 Å)
Cite:Structural basis for the regulation of maternal embryonic leucine zipper kinase.
Plos One, 8, 2013
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