Author results

2WII
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COMPLEMENT C3B IN COMPLEX WITH FACTOR H DOMAINS 1-4
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR H
Authors:Wu, J., Janssen, B.J.C., Gros, P.
Deposit date:2009-05-12
Release date:2009-06-09
Last modified:2009-08-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Complement Fragment C3B-Factor H and Implications for Host Protection by Complement Regulators.
Nat.Immunol., 10, 2009
1A94
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STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES
Descriptor:HIV PROTEASE, PEPTIDE
Authors:Wu, J., Adomat, J.M., Ridky, T.W., Louis, J.M., Leis, J., Harrison, R.W., Weber, I.T.
Deposit date:1998-04-16
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
1BAI
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CRYSTAL STRUCTURE OF ROUS SARCOMA VIRUS PROTEASE IN COMPLEX WITH INHIBITOR
Descriptor:ROUS SARCOMA VIRUS PROTEASE, INHIBITOR
Authors:Wu, J., Adomat, J.M., Ridky, T.W., Louis, J.M., Leis, J., Harrison, R.W., Weber, I.T.
Deposit date:1998-04-17
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
1SYK
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CRYSTAL STRUCTURE OF E230Q MUTANT OF CAMP-DEPENDENT PROTEIN KINASE REVEALS UNEXPECTED APOENZYME CONFORMATION
Descriptor:cAMP-dependent protein kinase, alpha-catalytic subunit (E.C.2.7.1.37)
Authors:Wu, J., Yang, J., Madhusudan, N., Xuong, N.H., Ten Eyck, L.F., Taylor, S.S.
Deposit date:2004-04-01
Release date:2005-05-17
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.
Protein Sci., 14, 2005
1ZTQ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF MMP-13 COMPLEXED WITH WAY-033
Descriptor:Crystal structure of the catalytic domain of MMP-13 complexed with WAY-033
Authors:Wu, J., Rush III, T.S., Hotchandani, R., Du, X., Geck, M., Collins, E., Xu, Z.B., Skotnicki, J., Levin, J.I., Lovering, F.
Deposit date:2005-05-27
Release date:2006-05-30
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of potent and selective MMP-13 inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
2P6E
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CRYSTAL STRUCTURES OF SACCHAROMYCES CEREVISIAE N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA
Descriptor:Glycylpeptide N-tetradecanoyltransferase (E.C.2.3.1.97)
Authors:Wu, J., Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6F
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CRYSTAL STRUCTURES OF SACCHAROMYCES CEREVISIAE N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA AND INHIBITORS
Descriptor:Glycylpeptide N-tetradecanoyltransferase (E.C.2.3.1.97)
Authors:Wu, J., Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6G
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CRYSTAL STRUCTURES OF SACCHAROMYCES CEREVISIAE N-MYRISTOYLTRANSFERASE WITH BOUND MYRISTOYL-COA AND INHIBITORS
Descriptor:Glycylpeptide N-tetradecanoyltransferase (E.C.2.3.1.97)
Authors:Wu, J., Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
3D94
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CRYSTAL STRUCTURE OF THE INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR KINASE IN COMPLEX WITH PQIP
Descriptor:Insulin-like growth factor 1 receptor beta chain (E.C.2.7.1.112, 2.7.10.1)
Authors:Wu, J., Li, W., Miller, W.T., Hubbard, S.R.
Deposit date:2008-05-26
Release date:2008-07-29
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor
Embo J., 27, 2008
1EHB
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CRYSTAL STRUCTURE OF RECOMBINANT TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
Descriptor:CRYSTAL STRUCTURE OF RECOMBINANT TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
Authors:Wu, J., Gan, J.-H., Xia, Z.-X., Wang, Y.-H., Wang, W.-H., Xue, L.-L., Xie, Y., Huang, Z.-X.
Deposit date:2000-02-20
Release date:2000-08-09
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant.
Proteins, 40, 2000
1ES1
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CRYSTAL STRUCTURE OF VAL61HIS MUTANT OF TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
Descriptor:CYTOCHROME B5
Authors:Wu, J., Gan, J.-H., Xia, Z.-X., Wang, Y.-H., Wang, W.-H., Xue, L.-L., Xie, Y., Huang, Z.-X.
Deposit date:2000-04-07
Release date:2000-08-09
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant.
Proteins, 40, 2000
1M2I
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CRYSTAL STRUCTURE OF E44A/E56A MUTANT OF CYTOCHROME B5
Descriptor:cytochrome b5
Authors:Wu, J., Wang, Y.-H., Gan, J.-H., Wang, W.-H., Sun, B.-Y., Huang, Z.-X., Xia, Z.-X.
Deposit date:2002-06-24
Release date:2003-03-18
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Cytochrome b5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome c
Chin.J.Chem., 20, 2002
1M2M
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CRYSTAL STRUCTURE OF E44A/E48A/E56A/D60A MUTANT OF CYTOCHROME B5
Descriptor:cytochrome b5
Authors:Wu, J., Wang, Y.-H., Gan, J.-H., Wang, W.-H., Sun, B.-Y., Huang, Z.-X., Xia, Z.-X.
Deposit date:2002-06-24
Release date:2003-03-18
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Cytochrome b5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome c
Chin.J.Chem., 20, 2002
1NE4
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CRYSTAL STRUCTURE OF RP-CAMP BINDING R1A SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J., Jones, J.M., Xuong, N.H., Taylor, S.S.
Deposit date:2002-12-10
Release date:2004-01-13
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1NE6
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CRYSTAL STRUCTURE OF SP-CAMP BINDING R1A SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J., Jones, J.M., Xuong, N.H., Taylor, S.S.
Deposit date:2002-12-10
Release date:2004-01-13
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1RL3
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CRYSTAL STRUCTURE OF CAMP-FREE R1A SUBUNIT OF PKA
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J., Brown, S., Xuong, N.-H., Taylor, S.S.
Deposit date:2003-11-24
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.
Structure, 12, 2004
1YKS
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CRYSTAL STRUCTURE OF YELLOW FEVER VIRUS NS3 HELICASE
Descriptor:Genome polyprotein [contains: Flavivirin protease NS3 catalytic subunit]
Authors:Wu, J., Bera, A.K., Kuhn, R.J., Smith, J.L.
Deposit date:2005-01-18
Release date:2005-08-23
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.
J.Virol., 79, 2005
2QVS
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CRYSTAL STRUCTURE OF TYPE IIA HOLOENZYME OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase, alpha-catalytic subunit (E.C.2.7.11.11), cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:Wu, J., Brown, S.H.J., von Daake, S., Taylor, S.S.
Deposit date:2007-08-08
Release date:2007-10-23
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity.
Science, 318, 2007
3BU3
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CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH IRS2 KRLB PEPTIDE
Descriptor:Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta] (E.C.2.7.10.1), Insulin receptor substrate 2
Authors:Wu, J., Hubbard, S.R.
Deposit date:2007-12-31
Release date:2008-02-19
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3BU5
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CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH IRS2 KRLB PEPTIDE AND ATP
Descriptor:---
Authors:Wu, J., Hubbard, S.R.
Deposit date:2007-12-31
Release date:2008-02-19
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3BU6
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CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH IRS2 KRLB PHOSPHOPEPTIDE
Descriptor:---
Authors:Wu, J., Hubbard, S.R.
Deposit date:2007-12-31
Release date:2008-02-19
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3H0L
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STRUCTURE OF TRNA-DEPENDENT AMIDOTRANSFERASE GATCAB FROM AQUIFEX AEOLICUS
Descriptor:Glutamyl-tRNA(Gln) amidotransferase subunit A (E.C.6.3.5.-), Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (E.C.6.3.5.-), Glutamyl-tRNA(Gln) amidotransferase subunit C (E.C.6.3.5.-)
Authors:Wu, J., Bu, W., Sheppard, K., Kitabatake, M., Soll, D., Smith, J.L.
Deposit date:2009-04-09
Release date:2009-07-21
Last modified:2009-08-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
3H0M
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STRUCTURE OF TRNA-DEPENDENT AMIDOTRANSFERASE GATCAB FROM AQUIFEX AEOLICUS
Descriptor:Glutamyl-tRNA(Gln) amidotransferase subunit A (E.C.6.3.5.-), Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (E.C.6.3.5.-), Glutamyl-tRNA(Gln) amidotransferase subunit C (E.C.6.3.5.-)
Authors:Wu, J., Bu, W., Sheppard, K., Kitabatake, M., Soll, D., Smith, J.L.
Deposit date:2009-04-09
Release date:2009-07-21
Last modified:2009-08-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
3H0R
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STRUCTURE OF TRNA-DEPENDENT AMIDOTRANSFERASE GATCAB FROM AQUIFEX AEOLICUS
Descriptor:Glutamyl-tRNA(Gln) amidotransferase subunit A (E.C.6.3.5.-), Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (E.C.6.3.5.-), Glutamyl-tRNA(Gln) amidotransferase subunit C (E.C.6.3.5.-)
Authors:Wu, J., Bu, W., Sheppard, K., Kitabatake, M., Soll, D., Smith, J.L.
Deposit date:2009-04-10
Release date:2009-07-21
Last modified:2009-08-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
3DEH
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CRYSTAL STRUCTURES OF CASPASE-3 WITH BOUND ISOQUINOLINE-1,3,4-TRIONE DERIVATIVE INHIBITORS
Descriptor:Caspase-3 (E.C.3.4.22.56)
Authors:Wu, J., Du, J., Li, J., Ding, J.
Deposit date:2008-06-10
Release date:2008-09-02
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species
J.Biol.Chem., 283, 2008
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