Author results

2JR7
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SOLUTION STRUCTURE OF HUMAN DESR1
Descriptor:DPH3 homolog, ZINC ION
Authors:Wu, F., Wu, J., Shi, Y.
Deposit date:2007-06-21
Release date:2008-03-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human DESR1, a CSL zinc-binding protein
Proteins, 71, 2008
3OF7
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THE CRYSTAL STRUCTURE OF PRP20P FROM SACCHAROMYCES CEREVISIAE AND ITS BINDING PROPERTIES TO GSP1P AND HISTONES
Descriptor:Regulator of chromosome condensation
Authors:Wu, F., Liu, Y., Zhu, Z., Huang, H., Ding, B., Wu, J., Shi, Y.
Deposit date:2010-08-14
Release date:2011-03-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9A crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones.
J.Struct.Biol., 174, 2011
1TW0
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NATIVE CRYSTAL STRUCTURE OF SPE16
Descriptor:pathogenesis-related class 10 protein SPE-16
Authors:Wu, F., Wei, Z., Zhou, Z., Gong, W.
Deposit date:2004-06-30
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Native crystal structure of SPE16
to be published
1TXC
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COMPLEX CRYSTAL STRUCTURE OF SPE16 WITH ANS
Descriptor:pathogenesis-related class 10 protein SPE-16, 8-ANILINO-1-NAPHTHALENE SULFONATE
Authors:Wu, F., Wei, Z., Zhou, Z., Gong, W.
Deposit date:2004-07-02
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complex crystal structure of SPE16 with ANS
To be Published
3V1S
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SCAFFOLD TAILORING BY A NEWLY DETECTED PICTET-SPENGLERASE AC-TIVITY OF STRICTOSIDINE SYNTHASE (STR1): FROM THE COMMON TRYP-TOLINE SKELETON TO THE RARE PIPERAZINO-INDOLE FRAMEWORK
Descriptor:Strictosidine synthase, 2-(1H-indol-1-yl)ethanamine
Authors:Wu, F., Zhu, H., Sun, L., Rajendran, C., Wang, M., Ren, X., Panjikar, S., Cherkasov, A., Zou, H., Stoeckigt, J.
Deposit date:2011-12-10
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.328 Å)
Cite:Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
J.Am.Chem.Soc., 134, 2012
5J3J
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CRYSTAL STRUCTURE OF HUMAN DPP-IV IN COMPLEX WITH HL1
Descriptor:Dipeptidyl peptidase 4, (2~{S},3~{R})-8,9-dimethoxy-3-[2,4,5-tris(fluoranyl)phenyl]-2,3-dihydro-1~{H}-benzo[f]chromen-2-amine, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wu, F., Li, H., Zhao, Z., Zhu, L., Xu, H., Li, S.
Deposit date:2016-03-31
Release date:2017-04-05
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of human DPP-IV in complex with HL1
To Be Published
2M9M
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SOLUTION STRUCTURE OF ERCC4 DOMAIN OF HUMAN FAAP24
Descriptor:Fanconi anemia-associated protein of 24 kDa
Authors:Wu, F., Han, X., Shi, C., Gong, W., Tian, C.
Deposit date:2013-06-18
Release date:2013-09-18
Method:SOLUTION NMR
Cite:Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response
Cell Res., 2013
2M9N
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SOLUTION STRUCTURE OF (HHH)2 DOMAIN OF HUMAN FAAP24
Descriptor:Fanconi anemia-associated protein of 24 kDa
Authors:Wu, F., Han, X., Shi, C., Gong, W., Tian, C.
Deposit date:2013-06-18
Release date:2013-09-18
Method:SOLUTION NMR
Cite:Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response
Cell Res., 2013
2MVT
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SOLUTION STRUCTURE OF SCOLOPTOXIN SSD609 FROM SCOLOPENDRA MUTILANS
Descriptor:Scoloptoxin SSD609
Authors:Wu, F., Sun, P., Wang, C., He, Y., Zhang, L., Tian, C.
Deposit date:2014-10-14
Release date:2015-09-23
Method:SOLUTION NMR
Cite:A distinct three-helix centipede toxin SSD609 inhibits Iks channels by interacting with the KCNE1 auxiliary subunit.
Sci Rep, 5, 2015
4XRX
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CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH (E)-5-((1-METHYL-5-OXO-2-THIOXOIMIDAZOLIDIN-4-YLIDENE)METHYL)PYRIDIN-2(1H)-ONE
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one
Authors:Zheng, B., Wu, F., Jiang, H., Kogiso, M., Yao, Y., Zhou, C., Li, X., Song, Y.
Deposit date:2015-01-21
Release date:2015-12-09
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
4XS3
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CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH (E)-1-BENZYL-5-((1-METHYL-5-OXO-2-THIOXOIMIDAZOLIDIN-4-YLIDENE)METHYL)PYRIDIN-2(1H)-ONE
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, B., Wu, F., Jiang, H., Kogiso, M., Yao, Y., Zhou, C., Li, X., Song, Y.
Deposit date:2015-01-21
Release date:2016-07-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.291 Å)
Cite:Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
5E6N
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CRYSTAL STRUCTURE OF C. ELEGANS LGG-2
Descriptor:Protein lgg-2
Authors:Qi, X., Ren, J.Q., Wu, F., Zhang, H., Feng, W.
Deposit date:2015-10-10
Release date:2016-01-06
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy
Mol.Cell, 60, 2015
5E6O
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CRYSTAL STRUCTURE OF C. ELEGANS LGG-2 BOUND TO AN AIM/LIR MOTIF
Descriptor:Protein lgg-2, TRP-GLU-GLU-LEU
Authors:Qi, X., Ren, J.Q., Wu, F., Zhang, H., Feng, W.
Deposit date:2015-10-10
Release date:2016-01-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy
Mol.Cell, 60, 2015
5EGG
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CRYSTAL STRUCTURE OF HUMAN UBIQUITIN-CONJUGATING ENZYME UBCH5C
Descriptor:Ubiquitin-conjugating enzyme E2 D3
Authors:Zhu, L., Li, H., Wu, F., Zhu, J.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
5X0S
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SOLUTION NMR STRUCTURE OF PEPTIDE TOXIN SSTX FROM SCOLOPENDRA SUBSPINIPES MUTILANS
Descriptor:SsTx
Authors:Wu, F., Luo, L., Qu, D., Zhang, L., Tian, C., Lai, R.
Deposit date:2017-01-23
Release date:2018-01-24
Last modified:2018-02-28
Method:SOLUTION NMR
Cite:Centipedes subdue giant prey by blocking KCNQ channels
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1YOP
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THE SOLUTION STRUCTURE OF KTI11P
Descriptor:Kti11p, ZINC ION
Authors:Sun, J., Zhang, J., Wu, F., Xu, C., Li, S., Zhao, W., Wu, Z., Wu, J., Zhou, C.-Z., Shi, Y.
Deposit date:2005-01-28
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Biochemistry, 44, 2005
5VEW
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STRUCTURE OF THE HUMAN GLP-1 RECEPTOR COMPLEX WITH PF-06372222
Descriptor:Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.
Deposit date:2017-04-05
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
5VEX
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STRUCTURE OF THE HUMAN GLP-1 RECEPTOR COMPLEX WITH NNC0640
Descriptor:Glucagon-like peptide 1 receptor, Endolysin chimera, 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide
Authors:Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.
Deposit date:2017-04-05
Release date:2017-05-17
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
2LW3
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SOLUTION STRUCTURE OF THE SOLUBLE DOMAIN OF MMPS4 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Putative membrane protein mmpS4
Authors:Xi, Z., Sun, P., Wang, W., Lai, C., Wu, F., Tian, C.
Deposit date:2012-07-19
Release date:2013-03-13
Method:SOLUTION NMR
Cite:Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis
Plos Pathog., 9, 2013
2M0Q
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SOLUTION NMR ANALYSIS OF INTACT KCNE2 IN DETERGENT MICELLES DEMONSTRATE A STRAIGHT TRANSMEMBRANE HELIX
Descriptor:Potassium voltage-gated channel subfamily E member 2
Authors:Lai, C., Li, P., Chen, L., Zhang, L., Wu, F., Tian, C.
Deposit date:2012-11-01
Release date:2014-04-30
Method:SOLUTION NMR
Cite:Solution NMR analysis of intact KCNE2 in detergent micelles demonstrate a straight transmembrane helix
To be Published
2MJY
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SOLUTION STRUCTURE OF SYNTHETIC MAMBA-1 PEPTIDE
Descriptor:Mambalgin-1
Authors:He, Y., Wu, F., Tian, C.
Deposit date:2014-01-21
Release date:2015-01-28
Method:SOLUTION NMR
Cite:One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1
Chem.Commun.(Camb.), 50, 2014
2MRM
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SOLUTION STRUCTURE OF THE RHODANESE DOMAIN OF YGAP FROM E. COLI
Descriptor:Membrane protein
Authors:Wang, W., Zhou, P., Tian, C., Wu, F.
Deposit date:2014-07-12
Release date:2014-10-08
Method:SOLUTION NMR
Cite:Fast conformational exchange between the sulfur-free and persulfide-bound rhodanese domain of E. coli YgaP
Biochem.Biophys.Res.Commun., 452, 2014
3DET
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STRUCTURE OF THE E148A, Y445A DOUBLY UNGATED MUTANT OF E.COLI CLC_EC1, CL-/H+ ANTIPORTER
Descriptor:H(+)/Cl(-) exchange transporter clcA, Fab fragment, Heavy chain, ...
Authors:Jayaram, H., Accardi, A., Wu, F., Williams, C., Miller, C.
Deposit date:2008-06-10
Release date:2008-06-17
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
3NCY
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X-RAY CRYSTAL STRUCTURE OF AN ARGININE AGMATINE ANTIPORTER (ADIC) IN COMPLEX WITH A FAB FRAGMENT
Descriptor:AdiC, Fab Heavy chain, Fab Light chain
Authors:Fang, Y., Jayaram, H., Shane, T., Komalkova-Partensky, L., Wu, F., Williams, C., Xiong, Y., Miller, C.
Deposit date:2010-06-06
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of a prokaryotic virtual proton pump at 3.2 A resolution.
Nature, 460, 2009
3ND0
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X-RAY CRYSTAL STRUCTURE OF A SLOW CYANOBACTERIAL CL-/H+ ANTIPORTER
Descriptor:Sll0855 protein, CHLORIDE ION
Authors:Jayaram, H., Robertson, J., Wu, F., Williams, C., Miller, C.
Deposit date:2010-06-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
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