Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6IID
DownloadVisualize
BU of 6iid by Molmil
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
Descriptor: DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-10-04
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.986 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
3QX3
DownloadVisualize
BU of 3qx3 by Molmil
Human topoisomerase IIbeta in complex with DNA and etoposide
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wu, C.C, Li, T.K, Farh, L, Lin, L.Y, Lin, T.S, Yu, Y.J, Yen, T.J, Chiang, C.W, Chan, N.L.
Deposit date:2011-03-01
Release date:2011-07-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.162 Å)
Cite:Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
Science, 333, 2011
4G0W
DownloadVisualize
BU of 4g0w by Molmil
Human topoisomerase iibeta in complex with DNA and ametantrone
Descriptor: 1,4-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2012-07-10
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4G0U
DownloadVisualize
BU of 4g0u by Molmil
Human topoisomerase IIbeta in complex with DNA and amsacrine
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2012-07-10
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4G0V
DownloadVisualize
BU of 4g0v by Molmil
Human topoisomerase iibeta in complex with DNA and mitoxantrone
Descriptor: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2012-07-10
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4J3N
DownloadVisualize
BU of 4j3n by Molmil
Human Topoisomerase Iibeta in complex with DNA
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2013-02-06
Release date:2013-10-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
5ZKI
DownloadVisualize
BU of 5zki by Molmil
Human EXOG-H140A in complex with duplex DNA
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-03-24
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.321 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
5ZKJ
DownloadVisualize
BU of 5zkj by Molmil
Human EXOG-H140A in complex with RNA/DNA hybrid duplex
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-03-24
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
8XA9
DownloadVisualize
BU of 8xa9 by Molmil
Human MGME1 in complex with 5'-overhang DNA
Descriptor: CALCIUM ION, DNA (11-MER), DNA (18-MER), ...
Authors:Wu, C.C, Mao, E.Y.C.
Deposit date:2023-12-03
Release date:2024-03-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural basis of how MGME1 processes DNA 5' ends to maintain mitochondrial genome integrity.
Nucleic Acids Res., 2024
7B7D
DownloadVisualize
BU of 7b7d by Molmil
Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N.
Deposit date:2020-12-10
Release date:2021-03-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome
To Be Published
5GWI
DownloadVisualize
BU of 5gwi by Molmil
Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873R
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.737 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
5GWK
DownloadVisualize
BU of 5gwk by Molmil
Human topoisomerase IIalpha in complex with DNA and etoposide
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wang, Y.R, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.152 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
5GWJ
DownloadVisualize
BU of 5gwj by Molmil
Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873S
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.566 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
4M2F
DownloadVisualize
BU of 4m2f by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-canavanine
Descriptor: FE (III) ION, L-CANAVANINE, L-arginine beta-hydroxylase
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M23
DownloadVisualize
BU of 4m23 by Molmil
Crystal structure of non-heme iron oxygenase OrfP
Descriptor: L-arginine beta-hydroxylase
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2M
DownloadVisualize
BU of 4m2m by Molmil
Crystal structure of PLP-dependent cyclase OrfR in complex with PLP-L-Arg
Descriptor: ARGININE, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2I
DownloadVisualize
BU of 4m2i by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe
Descriptor: FE (III) ION, L-arginine beta-hydroxylase
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M26
DownloadVisualize
BU of 4m26 by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe, succinate, and (3S)-hydroxy-L-Arg
Descriptor: (2S,3S)-3-HYDROXYARGININE, 2-OXOGLUTARIC ACID, FE (III) ION, ...
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2G
DownloadVisualize
BU of 4m2g by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe, succinate, and (3R,4R)-dihydroxy-L-Arg
Descriptor: FE (III) ION, L-arginine beta-hydroxylase, SUCCINIC ACID, ...
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M25
DownloadVisualize
BU of 4m25 by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and alpha-ketoglutaric acid
Descriptor: 2-OXOGLUTARIC ACID, FE (III) ION, L-arginine beta-hydroxylase
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M27
DownloadVisualize
BU of 4m27 by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg
Descriptor: ARGININE, FE (III) ION, L-arginine beta-hydroxylase, ...
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2K
DownloadVisualize
BU of 4m2k by Molmil
Crystal structure of PLP-dependent cyclase OrfR in complex with PLP
Descriptor: Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2E
DownloadVisualize
BU of 4m2e by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-homoarginine
Descriptor: FE (III) ION, L-HOMOARGININE, L-arginine beta-hydroxylase
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2J
DownloadVisualize
BU of 4m2j by Molmil
Crystal structure of PLP-dependent cyclase OrfR in complex with Au
Descriptor: Aminotransferase, GOLD ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
4M2C
DownloadVisualize
BU of 4m2c by Molmil
Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and D-Arg
Descriptor: D-ARGININE, FE (III) ION, L-arginine beta-hydroxylase
Authors:Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
Deposit date:2013-08-05
Release date:2014-06-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon