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5DP3
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP4
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 3
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP5
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 4
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP6
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 7
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[N-(3-cyclopropylpropanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP7
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 5
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP8
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 8
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-{[(2-cyclopropylethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP9
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 9
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-{[(cyclobutylmethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DPA
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 6
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-acetyl-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
4GHQ
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE
Descriptor:3C proteinase
Authors:Chen, C., Wu, C., Cai, Q., Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J., Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
4GHT
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH AG7088
Descriptor:3C proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
Authors:Chen, C., Wu, C., Cai, Q., Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J., Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
1HKS
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SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
Descriptor:HEAT-SHOCK TRANSCRIPTION FACTOR
Authors:Vuister, G.W., Kim, S.-J., Orosz, A., Marquardt, J.L., Wu, C., Bax, A.
Deposit date:1994-07-18
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor.
Nat.Struct.Biol., 1, 1994
1HKT
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SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
Descriptor:HEAT-SHOCK TRANSCRIPTION FACTOR
Authors:Vuister, G.W., Kim, S.-J., Orosz, A., Marquardt, J.L., Wu, C., Bax, A.
Deposit date:1994-07-18
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor.
Nat.Struct.Biol., 1, 1994
5JMT
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CRYSTAL STRUCTURE OF ZIKA VIRUS NS3 HELICASE
Descriptor:NS3 helicase
Authors:Tian, H., Ji, X., Yang, X., Xie, W., Yang, K., Chen, C., Wu, C., Chi, H., Mu, Z., Wang, Z., Yang, H.
Deposit date:2016-04-29
Release date:2016-05-25
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:The crystal structure of Zika virus helicase: basis for antiviral drug design
Protein Cell, 7, 2016
5Z0R
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STRUCTURAL INSIGHT INTO THE ZIKA VIRUS CAPSID ENCAPSULATING THE VIRAL GENOME
Descriptor:Extracellular solute-binding protein family 1,viral genome protein, MALTOSE
Authors:Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Deposit date:2017-12-20
Release date:2018-04-11
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
5Z0V
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STRUCTURAL INSIGHT INTO THE ZIKA VIRUS CAPSID ENCAPSULATING THE VIRAL GENOME
Descriptor:Extracellular solute-binding protein family 1,viral genome protein, MALTOSE
Authors:Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Deposit date:2017-12-21
Release date:2018-04-11
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
1G47
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1ST LIM DOMAIN OF PINCH PROTEIN
Descriptor:PINCH PROTEIN, ZINC ION
Authors:Velyvis, A., Yang, Y., Wu, C., Qin, J.
Deposit date:2000-10-26
Release date:2001-02-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain.
J.Biol.Chem., 276, 2001
1MN4
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STRUCTURE OF NDT80 (RESIDUES 59-340) DNA-BINDING DOMAIN CORE
Descriptor:NDT80 PROTEIN
Authors:Lamoureux, J.S., Stuart, D., Tsang, R., Wu, C., Glover, J.N.M.
Deposit date:2002-09-04
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
1MNN
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STRUCTURE OF THE SPORULATION SPECIFIC TRANSCRIPTION FACTOR NDT80 BOUND TO DNA
Descriptor:5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*AP*AP*AP*AP*C)-3', 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*TP*GP*TP*CP*GP*C)-3', NDT80 protein
Authors:Lamoureux, J.S., Stuart, D., Tsang, R., Wu, C., Glover, J.N.
Deposit date:2002-09-05
Release date:2002-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
1NYP
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4TH LIM DOMAIN OF PINCH PROTEIN
Descriptor:PINCH protein, ZINC ION
Authors:Velyvis, A., Vaynberg, J., Vinogradova, O., Zhang, Y., Wu, C., Qin, J.
Deposit date:2003-02-13
Release date:2003-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Nat.Struct.Biol., 10, 2003
1U5S
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NMR STRUCTURE OF THE COMPLEX BETWEEN NCK-2 SH3 DOMAIN AND PINCH-1 LIM4 DOMAIN
Descriptor:Cytoplasmic protein NCK2, PINCH protein, ZINC ION
Authors:Vaynberg, J., Fukuda, T., Vinogradova, O., Velyvis, A., Ng, L., Wu, C., Qin, J.
Deposit date:2004-07-28
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility.
Mol.Cell, 17, 2005
1X9X
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SOLUTION STRUCTURE OF DIMERIC SAM DOMAIN FROM MAPKKK STE11
Descriptor:Serine/threonine-protein kinase STE11
Authors:Bhattacharjya, S., Xu, P., Gingras, R., Shaykhutdinov, R., Wu, C., Whiteway, M., Ni, F.
Deposit date:2004-08-24
Release date:2005-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex.
J.Mol.Biol., 344, 2004
2JSS
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NMR STRUCTURE OF CHAPERONE CHZ1 COMPLEXED WITH HISTONE H2A.Z-H2B
Descriptor:Chimera of Histone H2B.1 and Histone H2A.Z, Uncharacterized protein YER030W
Authors:Zhou, Z., Feng, H., Hansen, D.F., Kato, H., Luk, E., Freedberg, D.I., Kay, L.E., Wu, C., Bai, Y.
Deposit date:2007-07-11
Release date:2008-05-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B.
Nat.Struct.Mol.Biol., 15, 2008
2K2R
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THE NMR STRUCTURE OF ALPHA-PARVIN CH2/PAXILLIN LD1 COMPLEX
Descriptor:Alpha-parvin, Paxillin
Authors:Wang, X., Fukuda, K., Byeon, I., Velyvis, A., Wu, C., Gronenborn, A., Qin, J.
Deposit date:2008-04-10
Release date:2008-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of {alpha}-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly.
J.Biol.Chem., 283, 2008
2L5A
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STRUCTURAL BASIS FOR RECOGNITION OF CENTROMERE SPECIFIC HISTONE H3 VARIANT BY NONHISTONE SCM3
Descriptor:Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4
Authors:Zhou, Z., Feng, H., Zhou, B., Ghirlando, R., Hu, K., Zwolak, A., Jenkins, L., Xiao, H., Tjandra, N., Wu, C., Bai, Y.
Deposit date:2010-10-28
Release date:2011-03-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
2LAS
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MOLECULAR DETERMINANTS OF PARALOGUE-SPECIFIC SUMO-SIM RECOGNITION
Descriptor:Small ubiquitin-related modifier 1, M-IR2_peptide
Authors:Namanja, A., Li, Y., Su, Y., Wong, S., Lu, J., Colson, L., Wu, C., Li, S., Chen, Y.
Deposit date:2011-03-20
Release date:2011-12-14
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis.
J.Biol.Chem., 287, 2012