Author results

5LNL
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CRYSTAL STRUCTURE OF HSF 1608-1749 PUTATIVE DOMAIN 1
分子名称:Hsf
著者Thomsen, M., Wright, J., Ridley, J., Goldman, A.
登録日2016-08-05
公開日2017-02-15
最終更新日2017-03-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of PD1, a Haemophilus surface fibril domain.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2XCF
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CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
分子名称:NS3 PROTEASE, NS4A, ZINC ION, ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Thommes, P., Ellis, M., Edge, C.M., Hubbard, J.A., Nassau, P., McDowell, B., Skarzynski, T.J., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
登録日2010-04-22
公開日2010-06-02
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XCN
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CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
分子名称:NS3 PROTEASE, NS4A, N-[(CYCLOPENTYLOXY)CARBONYL]-3-METHYL-L-VALYL-(4R)-N-{(1R)-3-HYDROXY-1-[HYDROXY(OXIDO)BORANYL]PROPYL}-4-(ISOQUINOLIN-1-YLOXY)-L-PROLINAMIDE, ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Thommes, P., Ellis, M., Edge, C.M., Hubbard, J.A., Nassau, P., McDowell, B., Skarzynski, T.J., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
登録日2010-04-23
公開日2010-06-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XNI
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PROTEIN-LIGAND COMPLEX OF A NOVEL MACROCYCLIC HCV NS3 PROTEASE INHIBITOR DERIVED FROM AMINO CYCLIC BORONATES
分子名称:NS3 PROTEASE, NS4A COFACTOR, (1-{[(10-tert-butyl-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19,23,23a-tetradecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosin-7(3H)-yl)carbonyl]amino}-3-hydroxypropyl)(trihydroxy)borate(1-), ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Zhou, Y., Li, Q., Plattner, J.J., Baker, S.J., Zhang, S., Kazmierski, W.M., Wright, L.L., Smith, G.K., Grimes, R.M., Crosby, R.M., Creech, K.L., Carballo, L.H., Slater, M.J., Jarvest, R.L., Thommes, P., Hubbard, J.A., Convery, M.A., Nassau, P.M., McDowell, W., Skarzynski, T.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., Pennicott, L.E., Zou, W., Wright, J.
登録日2010-08-02
公開日2011-08-17
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel Macrocyclic Hcv Ns3 Protease Inhibitors Derived from Alpha-Amino Cyclic Boronates.
Bioorg.Med.Chem.Lett., 20, 2010
2J6Y
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF PARTNER SWITCHING REGULATING THE ENVIRONMENTAL STRESS RESPONSE IN BACILLUS SUBTILIS
分子名称:PHOSPHOSERINE PHOSPHATASE RSBU
著者Hardwick, S.W., Pane-Farre, J., Delumeau, O., Marles-Wright, J., Murray, J.W., Hecker, M., Lewis, R.J.
登録日2006-10-05
公開日2007-02-13
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
2J6Z
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF PARTNER-SWITCHING REGULATING THE ENVIRONMENTAL STRESS RESPONSE IN B. SUBTILIS
分子名称:PHOSPHOSERINE PHOSPHATASE RSBU
著者Hardwick, S.W., Pane-Farre, J., Delumeau, O., Marles-Wright, J., Murray, J.W., Hecker, M., Lewis, R.J.
登録日2006-10-05
公開日2007-02-13
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
2J70
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF PARTNER-SWITCHING REGULATING THE ENVIRONMENTAL STRESS RESPONSE IN B. SUBTILIS
分子名称:PHOSPHOSERINE PHOSPHATASE RSBU
著者Hardwick, S.W., Pane-Farre, J., Delumeau, O., Marles-Wright, J., Murray, J.W., Hecker, M., Lewis, R.J.
登録日2006-10-05
公開日2007-02-13
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
2W8D
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DISTINCT AND ESSENTIAL MORPHOGENIC FUNCTIONS FOR WALL- AND LIPO- TEICHOIC ACIDS IN BACILLUS SUBTILIS
分子名称:PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE 2, MAGNESIUM ION, TETRAETHYLENE GLYCOL, ...
著者Schirner, K., Marles-Wright, J., Lewis, R.J., Errington, J.
登録日2009-01-15
公開日2009-03-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Distinct and Essential Morphogenic Functions for Wall- and Lipo-Teichoic Acids in Bacillus Subtilis
Embo J., 28, 2009
2XXP
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A WIDESPREAD FAMILY OF BACTERIAL CELL WALL ASSEMBLY PROTEINS
分子名称:CPS2A, MONO-TRANS, OCTA-CIS DECAPRENYL-PHOSPHATE, ...
著者Marles-Wright, J., Kawai, Y., Emmins, R., Ishikawa, S., Kuwano, M., Heinz, N., Cleverley, R.M., Bui, N.K., Ogasawara, N., Lewis, R.J., Vollmer, W., Daniel, R.A., Errington, J.
登録日2010-11-11
公開日2011-10-19
最終更新日2014-01-15
実験手法X-RAY DIFFRACTION (1.692 Å)
主引用文献A Widespread Family of Bacterial Cell Wall Assembly Proteins.
Embo J., 30, 2011
2XXQ
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A WIDESPREAD FAMILY OF BACTERIAL CELL WALL ASSEMBLY PROTEINS
分子名称:CPS2A, 1,2-ETHANEDIOL, ACETATE ION, ...
著者Marles-Wright, J., Kawai, Y., Emmins, R., Ishikawa, S., Kuwano, M., Heinz, N., Cleverley, R.M., Bui, N.K., Ogasawara, N., Lewis, R.J., Vollmer, W., Daniel, R.A., Errington, J.
登録日2010-11-11
公開日2011-10-19
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献A Widespread Family of Bacterial Cell Wall Assembly Proteins.
Embo J., 30, 2011
3TEL
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LYTR-CPS2A-PSR FAMILY PROTEIN WITH BOUND OCTAPRENYL PYROPHOSPHATE LIPID AND MANGANESE ION
分子名称:Cps2A, Integral membrane regulatory protein Wzg, (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, ...
著者Kawai, Y., Marles-Wright, J., Cleverley, R.M., Emmins, R., Ishikawa, S., Kuwano, M., Heinz, N., Khai Bui, N., Hoyland, C.N., Ogasawara, N., Lewis, R.J., Vollmer, W., Daniel, R.A., Errington, J.
登録日2011-08-15
公開日2011-10-12
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
3TEP
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LYTR-CPS2A-PSR FAMILY PROTEIN WITH BOUND OCTAPRENYL PYROPHOSPHATE LIPID AND MAGNESIUM ION
分子名称:CPS2A, Integral membrane regulatory protein Wzg, MAGNESIUM ION, ...
著者Kawai, Y., Marles-Wright, J., Cleverley, R.M., Emmins, R., Ishikawa, S., Kuwano, M., Heinz, N., Khai Bui, N., Hoyland, C.N., Ogasawara, N., Lewis, R.J., Vollmer, W., Daniel, R.A., Errington, J.
登録日2011-08-15
公開日2011-10-12
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
3TFL
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LYTR-CPS2A-PSR FAMILY PROTEIN WITH BOUND OCTAPRENYL PYROPHOSPHATE LIPID
分子名称:CPS2A, Integral membrane regulatory protein Wzg, 1,2-ETHANEDIOL, ...
著者Kawai, Y., Marles-Wright, J., Cleverley, R.M., Emmins, R., Ishikawa, S., Kuwano, M., Heinz, N., Khai Bui, N., Hoyland, C.N., Ogasawara, N., Lewis, R.J., Vollmer, W., Daniel, R.A., Errington, J.
登録日2011-08-16
公開日2011-10-12
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
3TTI
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CRYSTAL STRUCTURE OF JNK3 COMPLEXED WITH CC-930, AN ORALLY ACTIVE ANTI-FIBROTIC JNK INHIBITOR
分子名称:Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol, GLYCEROL
著者Plantevin-Krenitsky, V., Nadolny, L., Delgado, M., Ayala, L., Clareen, S., Hilgraf, R., Albers, R., Hegde, S., D'Sidocky, N., Sapienza, J., Wright, J., McCarrick, M., Bahmanyar, S., Chamberlain, P., Delker, S.L., Muir, J., Giegel, D., Xu, L., Celeridad, M., Lachowitzer, J., Bennett, B., Moghaddam, M., Khatsenko, O., Katz, J., Fan, R., Bai, A., Tang, Y., Shirley, M.A., Benish, B., Bodine, T., Blease, K., Raymon, H., Cathers, B.E., Satoh, Y.
登録日2011-09-14
公開日2012-02-01
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.
Bioorg.Med.Chem.Lett., 22, 2012
3TTJ
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CRYSTAL STRUCTURE OF JNK3 COMPLEXED WITH CC-359, A JNK INHIBITOR FOR THE PREVENTION OF ISCHEMIA-REPERFUSION INJURY
分子名称:Mitogen-activated protein kinase 10, 9-cyclopentyl-N~8~-(2-fluorophenyl)-N~2~-(4-methoxyphenyl)-9H-purine-2,8-diamine
著者Plantevin-Krenitsky, V., Delgado, M., Nadolny, L., Sahasrabudhe, K., Ayala, S., Clareen, S., Hilgraf, R., Albers, R., Kois, A., Hughes, K., Wright, J., Nowakowski, J., Sudbeck, E., Ghosh, S., Bahmanyar, S., Chamberlain, P., Muir, J., Cathers, B.E., Giegel, D., Xu, L., Celeridad, M., Moghaddam, M., Khatsenko, O., Omholt, P., Katz, J., Pai, S., Fan, R., Tang, Y., Shirley, M.A., Benish, B., Blease, K., Raymon, H., Bhagwat, S., Bennett, B., Satoh, Y.
登録日2011-09-14
公開日2012-01-25
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury.
Bioorg.Med.Chem.Lett., 22, 2012
5K1R
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STRUCTURE OF BURKHOLDERIA PSEUDOMALLEI K96243 SPHINGOSINE-1-PHOSPHATE LYASE BPSS2021
分子名称:Burkholderia pseudomallei sphingosine-1-phosphate lyase Bpss2021, PYRIDOXAL-5'-PHOSPHATE
著者Mclean, C.J., Campopiano, D.J., Marles-Wright, J.
登録日2016-05-18
公開日2016-11-02
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei.
J. Lipid Res., 58, 2017
2XTH
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K2PTBR6 BINDING TO LYSOZYME
分子名称:LYSOZYME C, HEXABROMOPLATINATE(IV)
著者Helliwell, J.R., Bell, A.M.T., Bryant, P., Fisher, S., Habash, J., Helliwell, M., Margiolaki, I., Kaenket, S., Watier, Y., Wright, J., Yalamanchili, S.K.
登録日2010-10-07
公開日2010-12-08
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Time-Dependent Analysis of K2Ptbr6 Binding to Lysozyme Studied by Protein Powder and Single Crystal X-Ray Analysis
Z.Kristallogr., 225, 2010
3QED
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THE STRUCTURE AND FUNCTION OF AN ARABINAN-SPECIFIC ALPHA-1,2-ARABINOFURANOSIDASE IDENTIFIED FROM SCREENING THE ACTIVITIES OF BACTERIAL GH43 GLYCOSIDE HYDROLASES
分子名称:Beta-xylosidase/alpha-L-arabinfuranosidase, gly43N, SULFATE ION, ...
著者Cartmell, A., Mckee, L.S., Pena, M., Larsbrink, J., Brumer, H., Lewis, R.J., Viks-Nielsen, A., Gilbert, H.J., Marles-Wright, J.
登録日2011-01-20
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The Structure and Function of an Arabinan-specific {alpha}-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases.
J.Biol.Chem., 286, 2011
3QEE
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THE STRUCTURE AND FUNCTION OF AN ARABINAN-SPECIFIC ALPHA-1,2-ARABINOFURANOSIDASE IDENTIFIED FROM SCREENING THE ACTIVITIES OF BACTERIAL GH43 GLYCOSIDE HYDROLASES
分子名称:Beta-xylosidase/alpha-L-arabinfuranosidase, gly43N, CALCIUM ION, ...
著者Cartmell, A., Mckee, L.S., Pena, M., Larsbrink, J., Brumer, H., Lewis, R.J., Viks-Nielsen, A., Gilbert, H.J., Marles-Wright, J.
登録日2011-01-20
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The Structure and Function of an Arabinan-specific {alpha}-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases.
J.Biol.Chem., 286, 2011
3QEF
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THE STRUCTURE AND FUNCTION OF AN ARABINAN-SPECIFIC ALPHA-1,2-ARABINOFURANOSIDASE IDENTIFIED FROM SCREENING THE ACTIVITIES OF BACTERIAL GH43 GLYCOSIDE HYDROLASES
分子名称:Beta-xylosidase/alpha-L-arabinfuranosidase, gly43N, CALCIUM ION, ...
著者Cartmell, A., Mckee, L.S., Pena, M., Larsbrink, J., Brumer, H., Lewis, R.J., Viks-Nielsen, A., Gilbert, H.J., Marles-Wright, J.
登録日2011-01-20
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.789 Å)
主引用文献The Structure and Function of an Arabinan-specific {alpha}-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases.
J.Biol.Chem., 286, 2011
2CDE
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STRUCTURE AND BINDING KINETICS OF THREE DIFFERENT HUMAN CD1D-ALPHA- GALACTOSYLCERAMIDE SPECIFIC T CELL RECEPTORS - INKT-TCR
分子名称:INKT-TCR
著者Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDF
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STRUCTURE AND BINDING KINETICS OF THREE DIFFERENT HUMAN CD1D-ALPHA- GALACTOSYLCERAMIDE-SPECIFIC T CELL RECEPTORS (TCR 5E)
分子名称:TCR 5E
著者Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDG
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STRUCTURE AND BINDING KINETICS OF THREE DIFFERENT HUMAN CD1D-ALPHA- GALACTOSYLCERAMIDE-SPECIFIC T CELL RECEPTORS (TCR 5B)
分子名称:TCR 5E
著者Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2VHD
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CRYSTAL STRUCTURE OF THE DI-HAEM CYTOCHROME C PEROXIDASE FROM PSEUDOMONAS AERUGINOSA - MIXED VALENCE FORM
分子名称:CYTOCHROME C551 PEROXIDASE, HEME C, CALCIUM ION
著者Echalier, A., Brittain, T., Wright, J., Boycheva, S., Mortuza, G.B., Fulop, V., Watmough, N.J.
登録日2007-11-20
公開日2008-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redox-Linked Structural Changes Associated with the Formation of a Catalytically Competent Form of the Diheme Cytochrome C Peroxidase from Pseudomonas Aeruginosa
Biochemistry, 47, 2008
2VSH
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SYNTHESIS OF CDP-ACTIVATED RIBITOL FOR TEICHOIC ACID PRECURSORS IN STREPTOCOCCUS PNEUMONIAE
分子名称:2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Baur, S., Marles-Wright, J., Buckenmaier, S., Lewis, R.J., Vollmer, W.
登録日2008-04-23
公開日2008-12-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis of Cdp-Activated Ribitol for Teichoic Acid Precursors in Streptococcus Pneumoniae.
J.Bacteriol., 191, 2009
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