Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1RJ2
DownloadVisualize
BU of 1rj2 by Molmil
Crystal structure of the DH/PH fragment of Dbs without bound GTPase
Descriptor: Guanine nucleotide exchange factor DBS [Fragment]
Authors:Worthylake, D.K, Rossman, K.L, Sondek, J.
Deposit date:2003-11-18
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the DH/PH fragment of Dbs without bound GTPase.
Structure, 12, 2004
1A43
DownloadVisualize
BU of 1a43 by Molmil
STRUCTURE OF THE HIV-1 CAPSID PROTEIN DIMERIZATION DOMAIN AT 2.6A RESOLUTION
Descriptor: HIV-1 CAPSID
Authors:Worthylake, D.K, Wang, H, Yoo, S, Sundquist, W.I, Hill, C.P.
Deposit date:1998-02-10
Release date:1999-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BAJ
DownloadVisualize
BU of 1baj by Molmil
HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
Descriptor: GAG POLYPROTEIN
Authors:Worthylake, D.K, Wang, H, Yoo, S, Sundquist, W.I, Hill, C.P.
Deposit date:1998-04-17
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1AYZ
DownloadVisualize
BU of 1ayz by Molmil
CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE UBIQUITIN-CONJUGATING ENZYME RAD6 (UBC2) AT 2.6A RESOLUTION
Descriptor: UBIQUITIN-CONJUGATING ENZYME RAD6
Authors:Worthylake, D.K, Prakash, S, Prakash, L, Hill, C.P.
Deposit date:1997-11-12
Release date:1998-08-26
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolution.
J.Biol.Chem., 273, 1998
1FOE
DownloadVisualize
BU of 1foe by Molmil
CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1
Descriptor: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1
Authors:Worthylake, D.K, Rossman, K.L, Sondek, J.
Deposit date:2000-08-27
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Nature, 408, 2000
7LXR
DownloadVisualize
BU of 7lxr by Molmil
Kinesin-like protein at 61F (Klp61f) bound to AMPPNP
Descriptor: 1,2-ETHANEDIOL, IODIDE ION, Kinesin-like protein Klp61F, ...
Authors:Worthylake, D.K, Wojcik, E.J.
Deposit date:2021-03-04
Release date:2022-11-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.744 Å)
Cite:Crystal Structure of the Klp61f motor domain bound to AMPPNP
To Be Published
5CJP
DownloadVisualize
BU of 5cjp by Molmil
The Structural Basis for Cdc42-Induced Dimerization of IQGAPs
Descriptor: Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ...
Authors:Worthylake, D.K, Boyapati, V.K, LeCour Jr, L.
Deposit date:2015-07-14
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.
Structure, 24, 2016
1AUM
DownloadVisualize
BU of 1aum by Molmil
HIV CAPSID C-TERMINAL DOMAIN (CAC146)
Descriptor: HIV CAPSID
Authors:Hill, C.P, Gamble, T.R, Yoo, S, Vajdos, F.F, Von Schwedler, U.K, Worthylake, D.K, Wang, H, Mccutcheon, J.P, Sundquist, W.I.
Deposit date:1997-08-29
Release date:1998-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
3FAY
DownloadVisualize
BU of 3fay by Molmil
Crystal structure of the GAP-related domain of IQGAP1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ras GTPase-activating-like protein IQGAP1
Authors:Kurella, V.B, Richard, J.M, Parke, C.L, Bellamy, H, Worthylake, D.K.
Deposit date:2008-11-18
Release date:2009-03-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the GTPase-activating protein-related domain from IQGAP1.
J.Biol.Chem., 284, 2009
2NZ8
DownloadVisualize
BU of 2nz8 by Molmil
N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1
Descriptor: ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein
Authors:Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J.
Deposit date:2006-11-22
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation
J.Mol.Biol., 368, 2007
3HQD
DownloadVisualize
BU of 3hqd by Molmil
Human kinesin Eg5 motor domain in complex with AMPPNP and Mg2+
Descriptor: Kinesin-like protein KIF11, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Parke, C.L, Wojcik, E.J, Kim, S, Worthylake, D.K.
Deposit date:2009-06-05
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism.
J.Biol.Chem., 285, 2010
3KEN
DownloadVisualize
BU of 3ken by Molmil
Human Eg5 in complex with S-trityl-L-cysteine
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ...
Authors:Parke, C.L, Wojcik, E.J, Kim, S, Worthylake, D.K.
Deposit date:2009-10-26
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
J.Biol.Chem., 285, 2010
1A8O
DownloadVisualize
BU of 1a8o by Molmil
HIV CAPSID C-TERMINAL DOMAIN
Descriptor: HIV CAPSID
Authors:Gamble, T.R, Yoo, S, Vajdos, F.F, Von Schwedler, U.K, Worthylake, D.K, Wang, H, Mccutcheon, J.P, Sundquist, W.I, Hill, C.P.
Deposit date:1998-03-27
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
1AK4
DownloadVisualize
BU of 1ak4 by Molmil
HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID
Descriptor: CYCLOPHILIN A, HIV-1 CAPSID
Authors:Hill, C.P, Gamble, T.R, Vajdos, F.F, Worthylake, D.K, Sundquist, W.I.
Deposit date:1997-05-28
Release date:1997-10-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Cell(Cambridge,Mass.), 87, 1996
1KZ7
DownloadVisualize
BU of 1kz7 by Molmil
Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42
Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Authors:Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1KZG
DownloadVisualize
BU of 1kzg by Molmil
DbsCdc42(Y889F)
Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Authors:Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1LB1
DownloadVisualize
BU of 1lb1 by Molmil
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
Descriptor: Guanine nucleotide exchange factor DBS, Transforming protein RhoA
Authors:Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J.
Deposit date:2002-04-01
Release date:2002-05-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
5L0O
DownloadVisualize
BU of 5l0o by Molmil
IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions
Descriptor: Ras GTPase-activating-like protein IQGAP1
Authors:Liu, J, Worthylake, D.
Deposit date:2016-07-27
Release date:2016-09-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
4H20
DownloadVisualize
BU of 4h20 by Molmil
Crystal Structure and Computational Modeling of the Fab Fragment from the Protective anti-Ricin Monoclonal Antibody RAC18
Descriptor: Heavy chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18, Light chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18
Authors:Zhao, Z, Worthylake, D.K, LeCour Jr, L.F, Maresh, G, Pincus, S.H.
Deposit date:2012-09-11
Release date:2012-10-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody.
Plos One, 7, 2012
2FJU
DownloadVisualize
BU of 2fju by Molmil
Activated Rac1 bound to its effector phospholipase C beta 2
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ...
Authors:Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J.
Deposit date:2006-01-03
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
3I6X
DownloadVisualize
BU of 3i6x by Molmil
Crystal structure of the calponin homology domain of IQGAP1
Descriptor: Ras GTPase-activating-like protein IQGAP1
Authors:Kurella, V.B.
Deposit date:2009-07-07
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
1KI1
DownloadVisualize
BU of 1ki1 by Molmil
Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42
Descriptor: G25K GTP-binding protein, placental isoform, SULFATE ION, ...
Authors:Snyder, J.T, Pruitt, W.M, Der, C.J, Sondek, J.
Deposit date:2001-12-02
Release date:2002-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
2ZKM
DownloadVisualize
BU of 2zkm by Molmil
Crystal Structure of Phospholipase C Beta 2
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2, CALCIUM ION
Authors:Hicks, S.N, Jezyk, M.R, Gershberg, S, Seifert, J.P, Harden, T.K, Sondek, J.
Deposit date:2008-03-26
Release date:2008-08-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:General and versatile autoinhibition of PLC isozymes
Mol.Cell, 31, 2008

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon