Author results

1R48
  • Download 1r48
  • View 1r48
Molmil generated image of 1r48
SOLUTION STRUCTURE OF THE C-TERMINAL CYTOPLASMIC DOMAIN RESIDUES 468-497 OF ESCHERICHIA COLI PROTEIN PROP
Descriptor:Proline/betaine transporter
Authors:Zoetewey, D.L., Tripet, B.P., Kutateladze, T.G., Overduin, M.J., Wood, J.M., Hodges, R.S.
Deposit date:2003-10-03
Release date:2003-12-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
2V0Z
  • Download 2v0z
  • View 2v0z
Molmil generated image of 2v0z
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 10 (ALISKIREN)
Descriptor:RENIN, N-ACETYL-D-GLUCOSAMINE, ALISKIREN
Authors:Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V10
  • Download 2v10
  • View 2v10
Molmil generated image of 2v10
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 9
Descriptor:RENIN, (2R,4S,5S,7S)-5-AMINO-N-BUTYL-4-HYDROXY-7-[4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL]-2,8-DIMETHYLNONANAMIDE
Authors:Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V11
  • Download 2v11
  • View 2v11
Molmil generated image of 2v11
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 6
Descriptor:RENIN, (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE
Authors:Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V12
  • Download 2v12
  • View 2v12
Molmil generated image of 2v12
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 8
Descriptor:RENIN, N-[(2S,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-7-METHYL-2-(1-METHYLETHYL)-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE
Authors:Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V13
  • Download 2v13
  • View 2v13
Molmil generated image of 2v13
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 7
Descriptor:RENIN, N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE
Authors:Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G.
Deposit date:2007-05-21
Release date:2008-07-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V16
  • Download 2v16
  • View 2v16
Molmil generated image of 2v16
CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 3
Descriptor:RENIN, METHYL (3R)-1-[(5S,6S,8R)-5-AMINO-9-BUTYLAMINO-6-HYDROXY-3,3,8-TRIMETHYL-9-OXO-NONANOYL]-3,4-DIHYDRO-2H-QUINOLINE-3-CARBOXYLATE
Authors:Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G.
Deposit date:2007-05-22
Release date:2008-07-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
4WEP
  • Download 4wep
  • View 4wep
Molmil generated image of 4wep
APO YEHZ FROM ESCERICHIA COLI
Descriptor:Putative osmoprotectant uptake system substrate-binding protein OsmF
Authors:Kimber, M.S., Lang, S., Mendoza, K., Wood, J.M.
Deposit date:2014-09-10
Release date:2015-09-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter.
Biochemistry, 54, 2015
4IWV
  • Download 4iwv
  • View 4iwv
Molmil generated image of 4iwv
CRYSTALS STRUCTURE OF HUMAN GLUCOKINASE IN COMPLEX WITH SMALL MOLECULE ACTIVATOR
Descriptor:Glucokinase isoform 3, SODIUM ION, ALPHA-D-GLUCOSE, ...
Authors:Ogg, D.J., Hargreaves, D., Gerhardt, S., Flavell, L., McAlister, M.
Deposit date:2013-01-24
Release date:2013-04-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets the discovery of AZD3651 and AZD9485
To be Published
1NNC
  • Download 1nnc
  • View 1nnc
Molmil generated image of 1nnc
INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) COMPLEXED WITH 4-GUANIDINO-NEU5AC2EN INHIBITOR
Descriptor:NEURAMINIDASE N9, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Varghese, J.N., Colman, P.M.
Deposit date:1995-03-15
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase.
Protein Sci., 4, 1995