Author results

3GJA
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CYTC3
Descriptor:CytC3, ACETATE ION
Authors:Wong, C., Drennan, C.L.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of an open active site conformation of nonheme iron halogenase CytC3
J.Am.Chem.Soc., 131, 2009
3GJB
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CYTC3 WITH FE(II) AND ALPHA-KETOGLUTARATE
Descriptor:CytC3, FE (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Wong, C., Drennan, C.L.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of an open active site conformation of nonheme iron halogenase CytC3
J.Am.Chem.Soc., 131, 2009
3U33
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CRYSTAL STRUCTURE OF THE E. COLI ADAPTIVE RESPONSE PROTEIN AIDB IN THE SPACE GROUP P3(2)
Descriptor:Putative acyl-CoA dehydrogenase AidB, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION
Authors:Wong, C., Jost, M., Drennan, C.L.
Deposit date:2011-10-04
Release date:2011-11-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Flavin-induced oligomerization in Escherichia coli adaptive response protein AidB.
Biochemistry, 50, 2011
3JB9
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CRYO-EM STRUCTURE OF THE YEAST SPLICEOSOME AT 3.6 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-splicing factor spp42, Pre-mRNA-splicing factor cwf10, U5 snRNA, ...
Authors:Yan, C., Hang, J., Wan, R., Huang, M., Wong, C., Shi, Y.
Deposit date:2015-08-09
Release date:2015-09-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349, 2015
5LQF
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CDK1/CYCLINB1/CKS2 IN COMPLEX WITH NU6102
Descriptor:Cyclin-dependent kinase 1, G2/mitotic-specific cyclin-B1, Cyclin-dependent kinases regulatory subunit 2, ...
Authors:Coxon, C.R., Anscombe, E., Harnor, S.J., Martin, M.P., Carbain, B.J., Hardcastle, I.R., Harlow, L.K., Korolchuk, S., Matheson, C.J., Noble, M.E., Newell, D.R., Turner, D.M., Sivaprakasam, M., Wang, L.Z., Wong, C., Golding, B.T., Griffin, R.J., Endicott, J.A., Cano, C.
Deposit date:2016-08-17
Release date:2017-01-11
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.
J. Med. Chem., 60, 2017
5NEV
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CDK2/CYCLIN A IN COMPLEX WITH COMPOUND 73
Descriptor:Cyclin-dependent kinase 2, Cyclin-A2, 4-[[6-(3-phenylphenyl)-7~{H}-purin-2-yl]amino]benzenesulfonamide
Authors:Coxon, C.R., Anscombe, E., Harnor, S.J., Martin, M.P., Carbain, B., Hardcastle, I.R., Harlow, L.K., Korolchuk, S., Matheson, C.J., Noble, M.E.M., Newell, D.R., Turner, D., Sivaprakasam, M., Wang, L.Z., Wong, C., Golding, B.T., Griffin, R.J., Cano, G.
Deposit date:2017-03-12
Release date:2017-03-29
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.
J. Med. Chem., 60, 2017
2WSM
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CRYSTAL STRUCTURE OF HYDROGENASE MATURATION FACTOR HYPB FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:HYDROGENASE EXPRESSION/FORMATION PROTEIN (HYPB), CHLORIDE ION
Authors:Wong, K.B., Li, T.
Deposit date:2009-09-08
Release date:2010-09-22
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for GTP-Dependent Dimerization of Hydrogenase Maturation Factor Hypb.
Plos One, 7, 2012
2NC3
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SOLUTION STRUCTURE OF N-ALLOSYLATED PIN1 WW DOMAIN
Descriptor:Pin1 WW Domain, D-ALLOPYRANOSE
Authors:Hsu, C., Park, S., Mortenson, D.E., Foley, B., Wang, X., Woods, R.J., Case, D.A., Powers, E.T., Wong, C., Dyson, H., Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2017-11-15
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC4
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SOLUTION STRUCTURE OF N-GALACTOSYLATED PIN1 WW DOMAIN
Descriptor:Pin1 WW Domain, BETA-D-GALACTOSE
Authors:Hsu, C., Park, S., Mortenson, D.E., Foley, B., Wang, X., Woods, R.J., Case, D.A., Powers, E.T., Wong, C., Dyson, H., Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2016-07-13
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC5
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SOLUTION STRUCTURE OF N-XYLOSYLATED PIN1 WW DOMAIN
Descriptor:Pin1 WW Domain, BETA-D-XYLOPYRANOSE
Authors:Hsu, C., Park, S., Mortenson, D.E., Foley, B., Wang, X., Woods, R.J., Case, D.A., Powers, E.T., Wong, C., Dyson, H., Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2016-07-13
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC6
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SOLUTION STRUCTURE OF N-L-IDOSYLATED PIN1 WW DOMAIN
Descriptor:Pin1 WW Domain, beta-L-idopyranose
Authors:Hsu, C., Park, S., Mortenson, D.E., Foley, B., Wang, X., Woods, R.J., Case, D.A., Powers, E.T., Wong, C., Dyson, H., Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2M9E
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN MUTANT 5-1
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
Deposit date:2013-06-07
Release date:2013-06-26
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9F
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN MUTANT 5-1G
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, N-ACETYL-D-GLUCOSAMINE
Authors:Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
Deposit date:2013-06-07
Release date:2013-06-26
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9I
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN VARIANT 6-1
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
Deposit date:2013-06-10
Release date:2013-06-26
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9J
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NMR SOLUTION STRUCTURE OF PIN1 WW DOMAIN MUTANT 6-1G
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, N-ACETYL-D-GLUCOSAMINE
Authors:Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
Deposit date:2013-06-10
Release date:2013-06-26
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
3TLH
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STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITHAN EFFICIENT INHIBITOR OF FIV PR
Descriptor:PROTEIN (PROTEASE), benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:Li, M., Lee, T., Morris, G., Laco, G., Wong, C., Olson, A., Elder, J., Wlodawer, A., Gustchina, A.
Deposit date:1998-12-03
Release date:1998-12-09
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
5FIV
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STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR
Descriptor:RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:Li, M., Lee, T., Morris, G., Laco, G., Wong, C., Olson, A., Elder, J., Wlodawer, A., Gustchina, A.
Deposit date:1998-12-02
Release date:1998-12-09
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
6FIV
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STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR
Descriptor:RETROPEPSIN, SULFATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:Li, M., Lee, T., Morris, G., Laco, G., Wong, C., Olson, A., Elder, J., Wlodawer, A., Gustchina, A.
Deposit date:1998-12-02
Release date:1998-12-09
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
5M51
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NEK2 BOUND TO ARYLAMINOPURINE COMPOUND 8
Descriptor:Serine/threonine-protein kinase Nek2, 3-[[6-(cyclohexylmethoxy)-9~{H}-purin-2-yl]amino]benzamide
Authors:Bayliss, R., Yeoh, S.
Deposit date:2016-10-20
Release date:2016-11-09
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
5M53
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NEK2 BOUND TO ARYLAMINOPURINE INHIBITOR 11
Descriptor:Serine/threonine-protein kinase Nek2, 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N},~{N}-dimethyl-benzamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Bayliss, R., Carr, K.H.
Deposit date:2016-10-20
Release date:2016-11-09
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
5M55
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NEK2 BOUND TO ARYLAMINOPURINE 71
Descriptor:Serine/threonine-protein kinase Nek2, 6-[(~{Z})-2-(diethylamino)ethenyl]-~{N}-phenyl-7~{H}-purin-2-amine, SULFATE ION, ...
Authors:Bayliss, R.
Deposit date:2016-10-20
Release date:2016-11-02
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
5M57
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NEK2 BOUND TO ARYLAMINOPURINE 6
Descriptor:Serine/threonine-protein kinase Nek2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE
Authors:Bayliss, R.
Deposit date:2016-10-20
Release date:2016-11-23
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-guided design of purine-based probes for selective Nek2 inhibition.
Oncotarget, 8, 2017
5C74
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STRUCTURE OF A NOVEL PROTEIN ARGININE METHYLTRANSFERASE
Descriptor:Protein arginine N-methyltransferase SFM1, SULFATE ION, NICKEL (II) ION
Authors:Lv, F., Ding, J.
Deposit date:2015-06-24
Release date:2016-01-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for Sfm1 functioning as a protein arginine methyltransferase
Cell Discov, 2015
5C77
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A NOVEL PROTEIN ARGININE METHYLTRANSFERASE
Descriptor:Protein arginine N-methyltransferase SFM1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lv, F., Zhang, T., Ding, J.
Deposit date:2015-06-24
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for Sfm1 functioning as a protein arginine methyltransferase
Cell Discov, 2015