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4X1O
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BU of 4x1o by Molmil
Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase from Catenulisporales acidiphilia
Descriptor: 16S rRNA (adenine(1408)-N(1))-methyltransferase
Authors:Witek, M.A, Conn, G.L.
Deposit date:2014-11-25
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5D1N
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BU of 5d1n by Molmil
Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase with its reaction by-product SAH from Catenulisporales acidiphilia
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Uncharacterized protein
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-08-04
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.713 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5EOV
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BU of 5eov by Molmil
C-terminal domain of the 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA.
Descriptor: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-11-10
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
5BW5
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Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase D21A mutant from Catenulisporales acidiphilia
Descriptor: 16S rRNA (adenine(1408)-N(1))-methyltransferase
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-06-05
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5BW4
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BU of 5bw4 by Molmil
Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase W203A mutant with cosubstrate SAM from Catenulisporales acidiphilia
Descriptor: 16S rRNA (adenine(1408)-N(1))-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-06-05
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5D1H
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BU of 5d1h by Molmil
Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase W203A mutant from Catenulisporales acidiphilia
Descriptor: Uncharacterized protein
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-08-04
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5KS2
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BU of 5ks2 by Molmil
RAWV_CTD (Helix form) of 16S/23S 2'-O-methyltransferase TlyA
Descriptor: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA, CHLORIDE ION
Authors:Kuiper, E.G, Conn, G.L.
Deposit date:2016-07-07
Release date:2017-01-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
5KYG
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RAWV_CTD (Loop Structure) of 16S/23S 2'-O-methyltransferase TlyA
Descriptor: Cytotoxin / haemolysin homologue TlyA, GLYCEROL
Authors:Kuiper, E.G, Conn, G.L.
Deposit date:2016-07-21
Release date:2017-01-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
7S0S
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BU of 7s0s by Molmil
M. tuberculosis ribosomal RNA methyltransferase TlyA bound to M. smegmatis 50S ribosomal subunit
Descriptor: 16S/23S rRNA (Cytidine-2'-O)-methyltransferase TlyA, 23S rRNA, 50S ribosomal protein L10, ...
Authors:Laughlin, Z.T, Dunham, C.M, Conn, G.L.
Deposit date:2021-08-31
Release date:2022-03-30
Last modified:2022-04-13
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
Proc.Natl.Acad.Sci.USA, 119, 2022
7JLZ
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Crystal structure of 30S ribosomal A1408 methyltransferase from an uncultured bacterium (UncKam)
Descriptor: 16S rRNA methylase, SULFATE ION
Authors:Nosrati, M, Conn, G.L.
Deposit date:2020-07-30
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Roles of conserved tryptophans in substrate recognition and catalysis by the aminoglycoside-resistance 16S rRNA (m1A1408) rRNA methyltransferases
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PDB entries from 2024-04-17

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