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1RVE
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THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA FRAGMENTS
Descriptor:ENDONUCLEASE EcoR V
Authors:Winkler, F.K.
Deposit date:1992-02-24
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments.
EMBO J., 12, 1993
4RVE
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THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA SEGMENTS
Descriptor:DNA (5'-D(*GP*GP*GP*AP*TP*AP*TP*CP*CP*C)-3'), PROTEIN (ECO RV (E.C.3.1.21.4))
Authors:Winkler, F.K., Banner, D.W., Oefner, C., Tsernoglou, D., Brown, R.S., Heathman, S.P., Bryan, R.K., Martin, P.D., Petratos, K., Wilso, K.S.
Deposit date:1993-02-18
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments.
EMBO J., 12, 1993
2RVE
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THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA SEGMENTS
Descriptor:DNA (5'-D(*CP*GP*AP*GP*CP*TP*CP*G)-3'), PROTEIN (ECO RV (E.C.3.1.21.4))
Authors:Winkler, F.K., Banner, D.W., Oefner, C., Tsernoglou, D., Brown, R.S., Heathman, S.P., Bryan, R.K., Martin, P.D., Petratos, K., Wilson, K.S.
Deposit date:1991-03-19
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments.
EMBO J., 12, 1993
1JRH
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COMPLEX (ANTIBODY/ANTIGEN)
Descriptor:ANTIBODY A6, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN
Authors:Winkler, F.K., Sogabe, S.
Deposit date:1997-09-23
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex.
J.Mol.Biol., 273, 1997
2TCL
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST COLLAGENASE COMPLEXED WITH AN INHIBITOR
Descriptor:FIBROBLAST COLLAGENASE, ZINC ION, SAMARIUM (III) ION, ...
Authors:Winkler, F.K., Borkakoti, N., D'Arcy, A.
Deposit date:1994-09-07
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.
Nat.Struct.Biol., 1, 1994
3MHY
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A NEW PII PROTEIN STRUCTURE
Descriptor:PII-like protein Pz, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Winkler, F.K., Truan, D., Li, X.D.
Deposit date:2010-04-09
Release date:2010-06-09
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A new P(II) protein structure identifies the 2-oxoglutarate binding site.
J.Mol.Biol., 400, 2010
1RVA
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MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), PROTEIN (ECO RV (E.C.3.1.21.4))
Authors:Kostrewa, D., Winkler, F.K.
Deposit date:1994-10-21
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution.
Biochemistry, 34, 1995
1RVB
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MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), PROTEIN (ECO RV (E.C.3.1.21.4)), MAGNESIUM ION
Authors:Kostrewa, D., Winkler, F.K.
Deposit date:1994-10-21
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution.
Biochemistry, 34, 1995
1RVC
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MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*T)-3'), DNA (5'-D(*AP*TP*CP*TP*T)-3'), PROTEIN (ECO RV (E.C.3.1.21.4)), ...
Authors:Kostrewa, D., Winkler, F.K.
Deposit date:1994-10-21
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution.
Biochemistry, 34, 1995
1XQO
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CRYSTAL STRUCTURE OF NATIVE PA-AGOG, 8-OXOGUANINE DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM
Descriptor:8-oxoguanine DNA glycosylase
Authors:Lingaraju, G.M., Sartori, A.A., Kostrewa, D., Prota, A.E., Jiricny, J., Winkler, F.K.
Deposit date:2004-10-13
Release date:2004-11-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
Structure, 13, 2005
1XQP
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CRYSTAL STRUCTURE OF 8-OXOGUANOSINE COMPLEXED PA-AGOG, 8-OXOGUANINE DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM
Descriptor:8-oxoguanine DNA glycosylase, 2'-DEOXY-8-OXOGUANOSINE
Authors:Lingaraju, G.M., Sartori, A.A., Kostrewa, D., Prota, A.E., Jiricny, J., Winkler, F.K.
Deposit date:2004-10-13
Release date:2004-11-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
Structure, 13, 2005
1DMT
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STRUCTURE OF HUMAN NEUTRAL ENDOPEPTIDASE COMPLEXED WITH PHOSPHORAMIDON
Descriptor:NEUTRAL ENDOPEPTIDASE, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Oefner, C., D'Arcy, A., Hennig, M., Winkler, F.K., Dale, G.E.
Deposit date:1999-12-15
Release date:2000-12-20
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon.
J.Mol.Biol., 296, 2000
1DRF
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CRYSTAL STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE
Descriptor:DIHYDROFOLATE REDUCTASE, SULFATE ION, FOLIC ACID
Authors:Oefner, C., D'Arcy, A., Winkler, F.K.
Deposit date:1990-08-09
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human dihydrofolate reductase complexed with folate.
Eur.J.Biochem., 174, 1988
1FG9
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3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER
Descriptor:INTERFERON GAMMA, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN
Authors:Thiel, D.J., le Du, M.-H., Walter, R.L., D'Arcy, A., Chene, C., Fountoulakis, M., Garotta, G., Winkler, F.K., Ealick, S.E.
Deposit date:2000-07-28
Release date:2000-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.
Structure Fold.Des., 8, 2000
1FR1
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REFINED CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM CITROBACTER FREUNDII INDICATES A MECHANISM FOR BETA-LACTAM HYDROLYSIS
Descriptor:BETA-LACTAMASE
Authors:Oefner, C., D'Arcy, A., Daly, J.J., Winkler, F.K.
Deposit date:2000-09-07
Release date:2001-01-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined crystal structure of beta-lactamase from Citrobacter freundii indicates a mechanism for beta-lactam hydrolysis.
Nature, 343, 1990
1FR6
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REFINED CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM CITROBACTER FREUNDII INDICATES A MECHANISM FOR BETA-LACTAM HYDROLYSIS
Descriptor:BETA-LACTAMASE, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid
Authors:Oefner, C., D'Arcy, A., Daly, J.J., Winkler, F.K.
Deposit date:2000-09-07
Release date:2001-01-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Refined crystal structure of beta-lactamase from Citrobacter freundii indicates a mechanism for beta-lactam hydrolysis.
Nature, 343, 1990
1IYK
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CRYSTAL STRUCTURE OF CANDIDA ALBICANS N-MYRISTOYLTRANSFERASE WITH MYRISTOYL-COA AND PEPTIDIC INHIBITOR
Descriptor:MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE, TETRADECANOYL-COA, [CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL]PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE
Authors:Sogabe, S., Fukami, T.A., Morikami, K., Shiratori, Y., Aoki, Y., D'Arcy, A., Winkler, F.K., Banner, D.W., Ohtsuka, T.
Deposit date:2002-08-29
Release date:2002-12-30
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors
CHEM.BIOL., 9, 2002
1IYL
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CRYSTAL STRUCTURE OF CANDIDA ALBICANS N-MYRISTOYLTRANSFERASE WITH NON-PEPTIDIC INHIBITOR
Descriptor:Myristoyl-CoA:Protein N-Myristoyltransferase, (1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRIDIN-3-YLMETHYL)-AMINO]-PROPOXY}-BENZOFURAN-2-YL)-METHANONE
Authors:Sogabe, S., Fukami, T.A., Morikami, K., Shiratori, Y., Aoki, Y., D'Arcy, A., Winkler, F.K., Banner, D.W., Ohtsuka, T.
Deposit date:2002-08-29
Release date:2002-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors
CHEM.BIOL., 9, 2002
1PDG
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CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB
Descriptor:PLATELET-DERIVED GROWTH FACTOR BB
Authors:Oefner, C., Darcy, A.D., Winkler, F.K., Eggimann, B., Hosnag, M.
Deposit date:1992-07-14
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human platelet-derived growth factor BB.
EMBO J., 11, 1992
1S9Z
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SYNTHETIC 17 AMINO ACID LONG PEPTIDE THAT FORMS A NATIVE-LIKE COILED-COIL AT AMBIENT TEMPERATURE AND AGGREGATES INTO AMYLOID-LIKE FIBRILS AT HIGHER TEMPERATURES.
Descriptor:SYNTHETIC COILED-COIL PEPTIDE, SODIUM ION, ZINC ION
Authors:Kammerer, R.A., Kostrewa, D., Zurdo, J., Detken, A., Garcia-Echeverria, C., Green, J.D., Muller, S.A., Meier, B.H., Winkler, F.K., Dobson, C.M., Steinmetz, M.O.
Deposit date:2004-02-06
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Exploring amyloid formation by a de novo design
Proc.Natl.Acad.Sci.USA, 101, 2004
1WU9
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE END-BINDING PROTEIN 1 (EB1)
Descriptor:Microtubule-associated protein RP/EB family member 1
Authors:Honnappa, S., John, C.M., Kostrewa, D., Winkler, F.K., Steinmetz, M.O.
Deposit date:2004-12-02
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural insights into the EB1-APC interaction
Embo J., 24, 2005
1XQE
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THE MECHANISM OF AMMONIA TRANSPORT BASED ON THE CRYSTAL STRUCTURE OF AMTB OF E. COLI.
Descriptor:Probable ammonium transporter, SULFATE ION, ACETATE ION
Authors:Zheng, L., Kostrewa, D., Berneche, S., Winkler, F.K., Li, X.-D.
Deposit date:2004-10-12
Release date:2004-10-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coli
Proc.Natl.Acad.Sci.USA, 101, 2004
1XQF
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THE MECHANISM OF AMMONIA TRANSPORT BASED ON THE CRYSTAL STRUCTURE OF AMTB OF E. COLI.
Descriptor:Probable ammonium transporter, SULFATE ION, ACETATE ION
Authors:Zheng, L., Kostrewa, D., Berneche, S., Winkler, F.K., Li, X.-D.
Deposit date:2004-10-12
Release date:2004-10-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coli
Proc.Natl.Acad.Sci.USA, 101, 2004
1YNP
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ALDO-KETO REDUCTASE AKR11C1 FROM BACILLUS HALODURANS (APO FORM)
Descriptor:oxidoreductase, SUCROSE, SODIUM ION, ...
Authors:Marquardt, T., Kostrewa, D., Winkler, F.K., Li, X.D.
Deposit date:2005-01-25
Release date:2005-12-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase
J.Mol.Biol., 354, 2005
1YNQ
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ALDO-KETO REDUCTASE AKR11C1 FROM BACILLUS HALODURANS (HOLO FORM)
Descriptor:oxidoreductase, SUCROSE, SODIUM ION, ...
Authors:Marquardt, T., Kostrewa, D., Winkler, F.K., Li, X.D.
Deposit date:2005-01-25
Release date:2005-12-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase
J.Mol.Biol., 354, 2005