Author results

3QE0
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A GALPHA-I1 P-LOOP MUTATION PREVENTS TRANSITION TO THE ACTIVATED STATE
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, KB752 peptide, MAGNESIUM ION, ...
著者Bosch, D.E., Willard, F.S., Kimple, A.J., Miley, M.J., Siderovski, D.P.
登録日2011-01-19
公開日2012-01-25
最終更新日2012-03-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis
Plos Pathog., 8, 2012
3QI2
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A GALPHA P-LOOP MUTATION PREVENTS TRANSITION TO THE ACTIVATED STATE: G42R BOUND TO RGS14 GOLOCO
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, Regulator of G-protein signaling 14, GUANOSINE-5'-DIPHOSPHATE, ...
著者Bosch, D.E., Willard, F.S., Kimple, A.J., Miley, M.J., Siderovski, D.P.
登録日2011-01-26
公開日2012-02-01
最終更新日2012-03-14
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis
Plos Pathog., 8, 2012
3UMS
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CRYSTAL STRUCTURE OF THE G202A MUTANT OF HUMAN G-ALPHA-I1
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
著者Lambert, N.A., Johnston, C.A., Cappell, S.D., Kuravi, S., Kimple, A.J., Willard, F.S., Siderovski, D.P.
登録日2011-11-14
公開日2012-02-08
実験手法X-RAY DIFFRACTION (2.343 Å)
主引用文献Correction for Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity
Proc.Natl.Acad.Sci.USA, 2012
1Y3A
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STRUCTURE OF G-ALPHA-I1 BOUND TO A GDP-SELECTIVE PEPTIDE PROVIDES INSIGHT INTO GUANINE NUCLEOTIDE EXCHANGE
分子名称:Guanine nucleotide-binding protein G(i), alpha-1 subunit, KB752 peptide, ...
著者Johnston, C.A., Willard, F.S., Jezyk, M.R., Fredericks, Z., Bodor, E.T., Jones, M.B., Blaesius, R., Harden, T.K., Sondek, J., Watts, V.J., Ramer, J.K., Siderovski, D.P.
登録日2004-11-24
公開日2005-07-12
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of G-Alpha-I1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange
Structure, 7, 2005
3ONW
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STRUCTURE OF A G-ALPHA-I1 MUTANT WITH ENHANCED AFFINITY FOR THE RGS14 GOLOCO MOTIF.
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, Regulator of G-protein signaling 14, GUANOSINE-5'-DIPHOSPHATE, ...
著者Bosch, D., Kimple, A.J., Sammond, D.W., Miley, M.J., Machius, M., Kuhlman, B., Willard, F.S., Siderovski, D.P.
登録日2010-08-30
公開日2010-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein {alpha} Subunit Mutants.
J.Biol.Chem., 286, 2011
3UMR
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CRYSTAL STRUCTURE OF THE G202D MUTANT OF HUMAN G-ALPHA-I1
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
著者Johnston, C.A., Afshar, K., Snyder, J.T., Tall, G.G., Gonczy, P., Siderovski, D.P., Willard, F.S.
登録日2011-11-14
公開日2012-10-24
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural Determinants Underlying the Temperature-sensitive Nature of a G-alpha Mutant in Asymmetric Cell Division of Caenorhabditis elegans
To be Published
4FID
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CRYSTAL STRUCTURE OF A HETEROTRIMERIC G-PROTEIN SUBUNIT FROM ENTAMOEBA HISTOLYTICA, EHG-ALPHA-1
分子名称:G protein alpha subunit, GUANOSINE-5'-DIPHOSPHATE
著者Bosch, D.E., Kimple, A.J., Muller, R.E., Gigure, P.M., Willard, F.S., Machius, M., Temple, B.R., Siderovski, D.P.
登録日2012-06-08
公開日2012-11-28
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica.
Plos Pathog., 8, 2012
4GOU
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CRYSTAL STRUCTURE OF AN RGS-RHOGEF FROM ENTAMOEBA HISTOLYTICA
分子名称:EhRGS-RhoGEF
著者Bosch, D.E., Kimple, A.J., Muller, R.E., Willard, F.S., Machius, M., Siderovski, D.P.
登録日2012-08-20
公開日2013-01-09
最終更新日2013-01-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis.
Structure, 21, 2013
4GQB
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CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX
分子名称:Protein arginine N-methyltransferase 5, Methylosome protein 50, Histone H4 peptide, ...
著者Antonysamy, S., Bonday, Z., Campbell, R., Doyle, B., Druzina, Z., Gheyi, T., Han, B., Jungheim, L.N., Qian, Y., Rauch, C., Russell, M., Sauder, J.M., Wasserman, S.R., Weichert, K., Willard, F.S., Zhang, A., Emtage, S.
登録日2012-08-22
公開日2012-10-17
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
1ZV4
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING 17 (RGSZ2)
分子名称:Regulator of G-protein signaling 17
著者Schoch, G.A., Jansson, A., Elkins, J.M., Haroniti, A., Niesen, F.H., Bunkoczi, G., Lee, W.H., Turnbull, A.P., Yang, X., Sundstrom, M., Arrowsmith, C., Edwards, A., Marsden, B., Gileadi, O., Ball, L., von Delft, F., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-06-01
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2A72
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING DOMAIN OF RGS7
分子名称:Regulator of G-protein signalling 7, CHLORIDE ION
著者Schoch, G.A., Johansson, C., Phillips, C., Debreczeni, J., Smee, C., Elkins, J.M., Sundstrom, M., Edwards, A., Arrowsmith, C., von Delft, F., Gileadi, O., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-07-04
公開日2005-07-12
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2AF0
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING DOMAIN OF RGS2
分子名称:Regulator of G-protein signaling 2
著者Papagrigoriou, E., Johannson, C., Phillips, C., Smee, C., Elkins, J.M., Weigelt, J., Arrowsmith, C., Edwards, A., Sundstrom, M., Von Delft, F., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-07-25
公開日2005-08-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2BT2
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING 16
分子名称:REGULATOR OF G-PROTEIN SIGNALING 16
著者Bunkoczi, G., Haroniti, A., Longman, E., Niesen, F., Soundararajan, M., Ball, L.J., von Delft, F., Doyle, D.A., Arrowsmith, C., Edwards, A., Sundstrom, M.
登録日2005-05-25
公開日2005-06-03
最終更新日2011-08-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits.
Proc.Natl.Acad.Sci.USA, 105, 2008
2BV1
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REGULATOR OF G-PROTEIN SIGNALLING 1 (HUMAN)
分子名称:REGULATOR OF G-PROTEIN SIGNALLING 1
著者Elkins, J.M., Yang, X., Soundararajan, M., Schoch, G.A., Haroniti, A., Sundstrom, M., Edwards, A., Arrowsmith, C., Doyle, D.A.
登録日2005-06-20
公開日2005-06-27
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2ES0
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STRUCTURE OF THE REGULATOR OF G-PROTEIN SIGNALING DOMAIN OF RGS6
分子名称:regulator of G-protein signalling 6
著者Schoch, G.A., Phillips, C., Turnbull, A., Niesen, F., Johansson, C., Elkins, J.M., Longman, E., Gilealdi, C., Sobott, F., Ball, L., Sundstrom, M., Edwards, A., Arrowsmith, C., von Delft, F., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-10-25
公開日2005-11-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2G83
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STRUCTURE OF ACTIVATED G-ALPHA-I1 BOUND TO A NUCLEOTIDE-STATE-SELECTIVE PEPTIDE: MINIMAL DETERMINANTS FOR RECOGNIZING THE ACTIVE FORM OF A G PROTEIN ALPHA SUBUNIT
分子名称:Guanine nucleotide-binding protein G(i), alpha-1 subunit, KB-1753 phage display peptide, ...
著者Johnston, C.A., Ramer, J.K., Blaesius, R., Kuhlman, B., Arshavsky, V.Y., Siderovski, D.P.
登録日2006-03-01
公開日2006-10-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Minimal Determinants for Binding Activated Galpha from the Structure of a Galpha(i1)-Peptide Dimer.
Biochemistry, 45, 2006
2GTP
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS1 AND ACTIVATED GI ALPHA 1
分子名称:Guanine nucleotide-binding protein G(i), alpha-1 subunit, Regulator of G-protein signaling 1, ...
著者Soundararajan, M., Turnbull, A.P., Ugochukwu, E., Gorrec, F., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-04-28
公開日2006-05-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2I59
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SOLUTION STRUCTURE OF RGS10
分子名称:Regulator of G-protein signaling 10
著者Fedorov, O., Higman, V.A., Diehl, A., Leidert, M., Lemak, A., Schmieder, P., Oschkinat, H., Elkins, J., Soundarajan, M., Doyle, D.A., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Ball, L.J., Structural Genomics Consortium (SGC)
登録日2006-08-24
公開日2006-10-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2IHB
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS10 AND ACTIVATED GI ALPHA 3
分子名称:Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signalling 10, TETRAFLUOROALUMINATE ION, ...
著者Soundararajan, M., Turnbull, A.P., Papagrigoriou, E., Pike, A.C.W., Bunkoczi, G., Ugochukwu, E., Gorrec, F., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-09-26
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2IHD
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CRYSTAL STRUCTURE OF HUMAN REGULATOR OF G-PROTEIN SIGNALING 8, RGS8
分子名称:Regulator of G-protein signaling 8, CHLORIDE ION
著者Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Salah, E., Gileadi, C., Burgess, N., Bhatia, C., Gileadi, O., Bray, J., Elkins, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-09-26
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2IK8
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS16 AND ACTIVATED GI ALPHA 1
分子名称:Guanine nucleotide-binding protein G(i), alpha-1 subunit, Regulator of G-protein signaling 16, ...
著者Soundararajan, M., Turnbull, A.P., Papagrigoriou, E., Debreczeni, J., Gorrec, F., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-10-02
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2JM5
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SOLUTION STRUCTURE OF THE RGS DOMAIN FROM HUMAN RGS18
分子名称:Regulator of G-protein signaling 18
著者Higman, V.A., Leidert, M., Bray, J., Elkins, J., Soundararajan, M., Doyle, D.A., Gileadi, C., Phillips, C., Schoch, G., Yang, X., Brockmann, C., Schmieder, P., Diehl, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oschkinat, H., Ball, L.J., Structural Genomics Consortium (SGC)
登録日2006-10-11
公開日2006-10-24
最終更新日2012-08-15
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2JNU
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SOLUTION STRUCTURE OF THE RGS DOMAIN OF HUMAN RGS14
分子名称:Regulator of G-protein signaling 14
著者Dowler, E.F., Diehl, A., Bray, J., Elkins, J., Soundararajan, M., Doyle, D.A., Gileadi, C., Phillips, C., Schoch, G.A., Yang, X., Brockmann, C., Leidert, M., Rehbein, K., Schmieder, P., Kuhne, R., Higman, V.A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oschkinat, H., Ball, L.J., Structural Genomics Consortium (SGC)
登録日2007-02-02
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2ODE
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS8 AND ACTIVATED GI ALPHA 3
分子名称:Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signaling 8, TETRAFLUOROALUMINATE ION, ...
著者Gileadi, C., Soundararajan, M., Turnbull, A.P., Elkins, J.M., Papagrigoriou, E., Pike, A.C.W., Bunkoczi, G., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-12-22
公開日2007-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2OWI
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SOLUTION STRUCTURE OF THE RGS DOMAIN FROM HUMAN RGS18
分子名称:Regulator of G-protein signaling 18
著者Higman, V.A., Leidert, M., Bray, J., Elkins, J., Soundararajan, M., Doyle, D.A., Gileadi, C., Phillips, C., Schoch, G., Yang, X., Brockmann, C., Schmieder, P., Diehl, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oschkinat, H., Ball, L.J., Structural Genomics Consortium (SGC)
登録日2007-02-16
公開日2007-02-27
最終更新日2012-08-15
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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