Author results

1WVN
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CRYSTAL STRUCTURE OF DOMAIN 3 OF HUMAN ALPHA POLYC BINDING PROTEIN
Descriptor:Poly(rC)-binding protein 1
Authors:Wilce, M.C.J., Wilce, J.A., Sidiqu, M.
Deposit date:2004-12-17
Release date:2005-04-05
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and RNA binding of the third KH domain of poly(C)-binding protein 1.
Nucleic Acids Res., 33, 2005
3RKW
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STRUCTURAL CHARACTERISATION OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase, BIOTINYL-5-AMP
Authors:Wilce, M.C.J., Pendini, N.R., Yap, M.Y.
Deposit date:2011-04-18
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterisation of staphylococcus aureus biotin protein ligase
To be published
3RKX
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STRUCTURAL CHARACTERISATION OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase
Authors:Wilce, M.C.J.
Deposit date:2011-04-18
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterisation of staphylococcus aureus biotin protein ligase
TO BE PUBLISHED
3RKY
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STRUCTURAL CHARACTERISATION OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase, BIOTIN
Authors:Wilce, M.C.J.
Deposit date:2011-04-18
Release date:2012-04-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.232 Å)
Cite:Structural characterisation of staphylococcus aureus biotin protein ligase
To be Published
3RIR
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CRYSTAL STRUCRTURE OF BIOTIN PROTEIN LIGASE FROM S. AUREUS
Descriptor:Biotin-[acetyl-CoA-carboxylase] ligase, BIOTINYL-5-AMP
Authors:Wilce, M.C.J.
Deposit date:2011-04-14
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Strucrture of Biotin Protein Ligase from S. aureus
To be published
1J0R
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CRYSTAL STRUCTURE OF THE REPLICATION TERMINATION PROTEIN MUTANT C110S
Descriptor:replication termination protein
Authors:Vivian, J.P., Hastings, A.F., Duggin, I.G., Wake, R.G., Wilce, M.C.J., Wilce, J.A.
Deposit date:2002-11-20
Release date:2003-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The impact of single cysteine residue mutations on the replication terminator protein
Biochem.Biophys.Res.Commun., 310, 2003
1ZTG
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HUMAN ALPHA POLYC BINDING PROTEIN KH1
Descriptor:POLY(RC)-BINDING PROTEIN 1, 5'-D(P*CP*CP*CP*TP*CP*CP*CP*T)-3'
Authors:Sidiqi, M., Wilce, J.A., Barker, A., Schmidgerger, J., Leedman, P.J., Wilce, M.C.J.
Deposit date:2005-05-27
Release date:2006-05-27
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Nucleic Acids Res., 40, 2012
2DPD
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CRYSTAL STRUCTURE OF THE REPLICATION TERMINATION PROTEIN IN COMPLEX WITH A PSEUDOSYMMETRIC B-SITE
Descriptor:5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*AP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*TP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', Replication termination protein
Authors:Vivian, J.P., Wilce, J., Wilce, M.C.J.
Deposit date:2006-05-09
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Crystal structure of the Replication Termination Protein in complex with a pseudosymmetric B-site
to be published
2DPU
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CRYSTAL STRUCTURE OF THE REPLICATION TERMINATION PROTEIN IN COMPLEX WITH A PSEUDOSYMMETRIC 21MER B-SITE DNA
Descriptor:5'-D(P*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*T)-3', Replication termination protein
Authors:Vivian, J.P., Wilce, J., Wilce, M.C.J.
Deposit date:2006-05-15
Release date:2007-05-15
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the replication termination protein in complex with a pseudosymmetric 21mer B-site DNA
to be published
2DQR
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CRYSTAL STRUCTURE OF THE REPLICATION TERMINATOR PROTEIN MUTANT RTP.E39K.R42Q
Descriptor:Replication termination protein
Authors:Vivian, J.P., Wilce, J.A., Wilce, M.C.J.
Deposit date:2006-05-29
Release date:2007-05-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal structure of the replication terminator protein mutant RTP.E39K.R42Q
to be published
2EFW
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CRYSTAL STRUCTURE OF THE RTP:NRB COMPLEX FROM BACILLUS SUBTILIS
Descriptor:DNA (5'-D(*DCP*DT*DAP*DTP*DGP*DTP*DAP*DCP*DCP*DAP*DAP*DAP*DTP*DGP*DTP*DTP*DCP*DAP*DGP*DTP*DC)-3'), DNA (5'-D(*DGP*DAP*DCP*DTP*DGP*DAP*DAP*DCP*DAP*DTP*DTP*DTP*DGP*DGP*DTP*DAP*DCP*DAP*DTP*DAP*DG)-3'), Replication termination protein
Authors:Vivian, J.P., Porter, C.J., Wilce, J.A., Wilce, M.C.J.
Deposit date:2007-02-26
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An asymmetric structure of the Bacillus subtilis replication terminator protein in complex with DNA
J.Mol.Biol., 370, 2007
3VKE
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CONTRIBUTION OF THE FIRST K-HOMOLOGY DOMAIN OF POLY(C)-BINDING PROTEIN 1 TO ITS AFFINITY AND SPECIFICITY FOR C-RICH OLIGONUCLEOTIDES
Descriptor:Poly(rC)-binding protein 1, DNA (5'-D(P*AP*CP*CP*CP*CP*A)-3')
Authors:Traore, D.A.K., Wilce, M.C.J., Wilce, J.A.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Nucleic Acids Res., 40, 2012
5TYI
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GRB7 SH2 WITH BICYCLIC PEPTIDE CONTAINING PY MIMETIC
Descriptor:Growth factor receptor-bound protein 7, Peptide inhibitor
Authors:Watson, G.M., Wilce, M.C.J., Wilce, J.A.
Deposit date:2016-11-20
Release date:2017-11-15
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
J. Med. Chem., 60, 2017
5U1Q
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GRB7-SH2 WITH BICYCLIC PEPTIDE INHIBITOR
Descriptor:Growth factor receptor-bound protein 7, LYS-PHE-GLU-GLY-TYR-ASP-ASN-GLU-CST, CHLORIDE ION
Authors:Watson, G.M., Wilce, M.C.J., Wilce, J.A.
Deposit date:2016-11-28
Release date:2017-11-15
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
J. Med. Chem., 60, 2017
2NO4
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CRYSTAL STRUCTURE ANALYSIS OF A DEHALOGENASE
Descriptor:(S)-2-haloacid dehalogenase IVA, SULFATE ION, CHLORIDE ION
Authors:Schmidberger, J.W., Wilce, M.C.J.
Deposit date:2006-10-24
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4
J.Mol.Biol., 368, 2007
2NO5
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CRYSTAL STRUCTURE ANALYSIS OF A DEHALOGENASE WITH INTERMEDIATE COMPLEX
Descriptor:(S)-2-haloacid dehalogenase IVA, CHLORIDE ION, SULFATE ION, ...
Authors:Schmidberger, J.W., Wilce, M.C.J.
Deposit date:2006-10-24
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4
J.Mol.Biol., 368, 2007
3BJX
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STRUCTURE OF A GROUP I HALOACID DEHALOGENASE FROM PSEUDOMONAS PUTIDA STRAIN PP3
Descriptor:Halocarboxylic acid dehalogenase DehI, SULFATE ION
Authors:Schmidberger, J.W., Wilce, M.C.J.
Deposit date:2007-12-05
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of DehI reveals a new alpha-haloacid dehalogenase fold and active-site mechanism
J.Mol.Biol., 378, 2008
1T3W
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CRYSTAL STRUCTURE OF THE E.COLI DNAG C-TERMINAL DOMAIN (RESIDUES 434 TO 581)
Descriptor:DNA primase, ACETIC ACID
Authors:Oakley, A.J., Loscha, K.V., Schaeffer, P.M., Liepinsh, E., Wilce, M.C.J., Otting, G., Dixon, N.E.
Deposit date:2004-04-28
Release date:2004-11-02
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal and solution structures of the helicase-binding domain of Escherichia coli primase
J.Biol.Chem., 280, 2005
1K5P
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HYDROLYTIC HALOALKANE DEHALOGENASE LINB FROM SPHINGOMONAS PAUCIMOBILIS UT26 AT 1.8A RESOLUTION
Descriptor:1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase, CHLORIDE ION, MAGNESIUM ION
Authors:Streltsov, V.A., Damborsky, J., Wilce, M.C.J.
Deposit date:2001-10-12
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates
Biochemistry, 42, 2003
1K63
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COMPLEX OF HYDROLYTIC HALOALKANE DEHALOGENASE LINB FROM SPHINGOMONAS PAUCIMOBILIS WITH UT26 2-BROMO-2-PROPENE-1-OL AT 1.8A RESOLUTION
Descriptor:1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase, BROMIDE ION, CHLORIDE ION, ...
Authors:Streltsov, V.A., Damborsky, J., Wilce, M.C.J.
Deposit date:2001-10-15
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates
Biochemistry, 42, 2003
1K6E
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COMPLEX OF HYDROLYTIC HALOALKANE DEHALOGENASE LINB FROM SPHINGOMONAS PAUCIMOBILIS UT26 WITH 1,2-PROPANEDIOL (PRODUCT OF DEHALOGENATION OF 1,2-DIBROMOPROPANE) AT 1.85A
Descriptor:HALOALKANE DEHALOGENASE, BROMIDE ION, CHLORIDE ION, ...
Authors:Streltsov, V.A., Prokop, Z., Damborsky, J., Nagata, Y., Oakley, A., Wilce, M.C.J.
Deposit date:2001-10-16
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates.
Biochemistry, 42, 2003
1R7O
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CRYSTAL STRUCTURE OF APO-MANNANASE 26A FROM PSUDOMONAS CELLULOSA
Descriptor:mannanase A, ZINC ION, SULFATE ION, ...
Authors:Oakley, A.J., Wilce, M.C.J.
Deposit date:2003-10-22
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural investigation of Mannanase 26A from Pseudomonas cellulosa reveals an induced fit mechanism and a non-substrate ligand binding site
To be published
2IY9
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CRYSTAL STRUCTURE OF THE A-SUBUNIT OF THE AB5 TOXIN FROM E. COLI
Descriptor:SUBA
Authors:Paton, A.W., Beddoe, T., Thorpe, C.M., Whisstock, J.C., Wilce, M.C.J., Rossjohn, J., Talbot, U.M., Paton, J.C.
Deposit date:2006-07-13
Release date:2006-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ab5 Subtilase Cytotoxin Inactivates the Endoplasmic Reticulum Chaperone Bip
Nature, 443, 2006
2MHC
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NMR STRUCTURE OF THE CATALYTIC DOMAIN OF THE LARGE SERINE RESOLVASE TNPX
Descriptor:TnpX
Authors:Headey, S.J., Sivakumaran, A., Adams, V., Rodgers, A.J.W., Rood, J.I., Scanlon, M.J., Wilce, M.C.J.
Deposit date:2013-11-20
Release date:2014-11-26
Method:SOLUTION NMR
Cite:Solution Structure and DNA Binding of the Catalytic of the Large Serine Resolvase Tnpx
To be Published
2WZM
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM ALDO-KETO REDUCTASE IN ITS APO AND LIGANDED FORM
Descriptor:ALDO-KETO REDUCTASE, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
Authors:Scoble, J., McAlister, A.D., Fulton, Z., Troy, S., Byres, E., Vivian, J.P., Brammananth, R., Wilce, M.C.J., Le Nours, J., Zaker-Tabrizi, L., Coppel, R.L., Crellin, P.K., Rossjohn, J., Beddoe, T.
Deposit date:2009-11-30
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase.
J.Mol.Biol., 398, 2010