Author results

1A16
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AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU
Descriptor:AMINOPEPTIDASE P, PROLINE, LEUCINE, ...
Authors:Wilce, M.C., Bond, C.S., Lilley, P.E., Dixon, N.E., Freeman, H.C., Guss, J.M.
Deposit date:1997-12-22
Release date:1999-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 95, 1998
2QMS
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CRYSTAL STRUCTURE OF A SIGNALING MOLECULE
Descriptor:Growth factor receptor-bound protein 7, SULFATE ION
Authors:Porter, C.J., Wilce, M.C., Wilce, J.A.
Deposit date:2007-07-16
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.
Bmc Struct.Biol., 7, 2007
4WWQ
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APO STRUCTURE OF THE GRB7 SH2 DOMAIN
Descriptor:Growth factor receptor-bound protein 7, MALONIC ACID
Authors:Watson, G.M., Ambaye, N.D., Wilce, M.C., Wilce, J.A.
Deposit date:2014-11-12
Release date:2015-09-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
J.Med.Chem., 58, 2015
4X6S
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GRB7 SH2 DOMAIN WITH PHOSPHOTYROSINE MIMETIC INHIBITOR PEPTIDE
Descriptor:Growth factor receptor-bound protein 7, Phosphotyrosine mimetic inhibitor peptide G7-TEM1
Authors:Watson, G.M., Panjikar, S., Wilce, M.C., Wilce, J.A.
Deposit date:2014-12-09
Release date:2015-09-23
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
J.Med.Chem., 58, 2015
1MJ5
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LINB (HALOALKANE DEHALOGENASE) FROM SPHINGOMONAS PAUCIMOBILIS UT26 AT ATOMIC RESOLUTION
Descriptor:1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase, MAGNESIUM ION, CHLORIDE ION
Authors:Oakley, A.J., Damborsky, J., Wilce, M.C.
Deposit date:2002-08-27
Release date:2003-08-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 A resolution: dynamics of catalytic residues.
Biochemistry, 43, 2004
1JLV
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ANOPHELES DIRUS SPECIES B GLUTATHIONE S-TRANSFERASES 1-3
Descriptor:glutathione transferase GST1-3, GLUTATHIONE
Authors:Oakley, A.J., Harnnoi, T., Udomsinprasert, R., Jirajaroenrat, K., Ketterman, A.J., Wilce, M.C.
Deposit date:2001-07-16
Release date:2002-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
Protein Sci., 10, 2001
1JLW
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ANOPHELES DIRUS SPECIES B GLUTATHIONE S-TRANSFERASES 1-4
Descriptor:glutathione transferase GST1-4
Authors:Oakley, A.J., Harnnoi, T., Udomsinprasert, R., Jirajaroenrat, K., Ketterman, A.J., Wilce, M.C.
Deposit date:2001-07-16
Release date:2002-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
Protein Sci., 10, 2001
2AK4
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CRYSTAL STRUCTURE OF SB27 TCR IN COMPLEX WITH HLA-B*3508-13MER PEPTIDE
Descriptor:HLA-B35 variant, Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, ...
Authors:Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N.A., Miles, J.J., Beddoe, T., Whisstock, J.C., Wilce, M.C., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Konstenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J.
Deposit date:2005-08-03
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
3KPL
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CRYSTAL STRUCTURE OF HLA B*4402 IN COMPLEX WITH EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPM
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CRYSTAL STRUCTURE OF HLA B*4402 IN COMPLEX WITH EEYLKAWTF, A MIMOTOPE
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPN
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CRYSTAL STRUCTURE OF HLA B*4403 IN COMPLEX WITH EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:MHC class I antigen, Beta-2-microglobulin, EEYLQAFTY, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPO
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CRYSTAL STRUCTURE OF HLA B*4403 IN COMPLEX WITH EEYLKAWTF, A MIMOTOPE
Descriptor:MHC class I antigen, Beta-2-microglobulin, EEYLKAWTF, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPP
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CRYSTAL STRUCTURE OF HLA B*4405 IN COMPLEX WITH EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPQ
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CRYSTAL STRUCTURE OF HLA B*4405 IN COMPLEX WITH EEYLKAWTF, A MIMOTOPE
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPR
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CRYSTAL STRUCTURE OF THE LC13 TCR IN COMPLEX WITH HLA B*4405 BOUND TO EEYLKAWTF A MIMOTOPE
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPS
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CRYSTAL STRUCTURE OF THE LC13 TCR IN COMPLEX WITH HLA B*4405 BOUND TO EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
1JAW
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AMINOPEPTIDASE P FROM E. COLI LOW PH FORM
Descriptor:AMINOPEPTIDASE P, MANGANESE (II) ION, ACETATE ION
Authors:Wilce, M.C.J., Bond, C.S., Lilley, P.E., Dixon, N.E., Freeman, H.C., Guss, J.M.
Deposit date:1997-12-22
Release date:1999-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AV4
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CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO-AND APO-FORMS: IMPLICATIONS FOR THE BIOGENESIS OF TOPA QUINONE
Descriptor:AMINE OXIDASE, COPPER (II) ION
Authors:Wilce, M.C.J., Guss, J.M., Freeman, H.C.
Deposit date:1997-09-24
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone.
Biochemistry, 36, 1997
1AVK
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CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO-AND APO-FORMS: IMPLICATIONS FOR THE BIOGENESIS OF TOPA QUINONE
Descriptor:AMINE OXIDASE
Authors:Wilce, M.C.J., Guss, J.M., Freeman, H.C., Tanizawa, K., Yamaguchi, H.
Deposit date:1997-09-16
Release date:1998-03-18
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone.
Biochemistry, 36, 1997
1AVL
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CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO-AND APO-FORMS: IMPLICATIONS FOR THE BIOGENESIS OF TOPA QUINONE
Descriptor:AMINE OXIDASE, COPPER (II) ION
Authors:Wilce, M.C.J., Guss, J.M., Freeman, H.C.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone.
Biochemistry, 36, 1997
1F4K
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CRYSTAL STRUCTURE OF THE REPLICATION TERMINATOR PROTEIN/B-SITE DNA COMPLEX
Descriptor:5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*AP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*TP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', REPLICATION TERMINATION PROTEIN
Authors:Wilce, J.A., Vivian, J.P., Hastings, A.F., Otting, G., Folmer, R.H.A., Duggin, I.G., Wake, R.G., Wilce, M.C.J.
Deposit date:2000-06-08
Release date:2001-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest
Nat.Struct.Biol., 8, 2001
5D0J
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GRB7 SH2 WITH INHIBITOR PEPTIDE
Descriptor:Growth factor receptor-bound protein 7, G7-TEdFP peptide, PHOSPHATE ION
Authors:Gunzburg, M.J., Watson, G.M., Wilce, J.A., Wilce, M.C.J.
Deposit date:2015-08-03
Release date:2016-06-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
5EEL
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GRB7 SH2 WITH BICYCLIC PEPTIDE INHIBITOR
Descriptor:Growth factor receptor-bound protein 7, Bicyclic Peptide Inhibitor, MALONIC ACID, ...
Authors:Watson, G.M., Gunzburg, M.J., Wilce, M.C.J., Wilce, J.A.
Deposit date:2015-10-23
Release date:2016-06-15
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
5EEQ
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GRB7 SH2 WITH THE G7-B1 BICYCLIC PEPTIDE INHIBITOR
Descriptor:Growth factor receptor-bound protein 7, Bicyclic Peptide Inhibitor, PHOSPHATE ION
Authors:Ambaye, N.D., Watson, G.M., Wilce, M.C.J., Wilce, G.M.
Deposit date:2015-10-23
Release date:2016-06-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
5ITH
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TIA-1 RRM2 RECOGNITION OF TARGET OLIGONUCLEOTIDE
Descriptor:Nucleolysin TIA-1 isoform p40, DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3')
Authors:Waris, S., Wilce, J.A., Wilce, M.C.
Deposit date:2016-03-16
Release date:2017-02-22
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:TIA-1 RRM23 binding and recognition of target oligonucleotides.
Nucleic Acids Res., 45, 2017