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Human brain aspartoacylase mutant Y231C complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor:	Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:	Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:	2014-06-05
Release date:	2014-07-30
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective. Biochemistry, 53, 2014

Human brain aspartoacylase mutant K213E complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor:	Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:	Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:	2013-09-26
Release date:	2014-07-30
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective. Biochemistry, 53, 2014

Human brain aspartoacylase mutant F295S complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor:	Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:	Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:	2013-09-17
Release date:	2014-07-30
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective. Biochemistry, 53, 2014

Human brain aspartoacylase mutant E285A complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor:	Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:	Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:	2013-10-31
Release date:	2014-07-30
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective. Biochemistry, 53, 2014