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1LDN
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BU of 1ldn by Molmil
STRUCTURE OF A TERNARY COMPLEX OF AN ALLOSTERIC LACTATE DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Wigley, D.B, Gamblin, S.J, Turkenburg, J.P, Dodson, E.J, Piontek, K, Muirhead, H, Holbrook, J.J.
Deposit date:1991-11-19
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution.
J.Mol.Biol., 223, 1992
7ZI4
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BU of 7zi4 by Molmil
Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B.
Deposit date:2022-04-07
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
To Be Published
2IGD
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BU of 2igd by Molmil
ANISOTROPIC STRUCTURE OF PROTEIN G IGG-BINDING DOMAIN III AT 1.1 ANGSTROM RESOLUTION
Descriptor: PROTEIN G
Authors:Butterworth, S, Lamzin, V.L, Wigley, D.B, Derrick, J.P, Wilson, K.S.
Deposit date:1997-04-30
Release date:1998-07-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Anisotropic Refinement of a Protein G Domain at 1.1 Angstrom Resolution
To be Published
1B04
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BU of 1b04 by Molmil
STRUCTURE OF THE ADENYLATION DOMAIN OF AN NAD+ DEPENDENT LIGASE
Descriptor: PROTEIN (DNA LIGASE)
Authors:Singleton, M.R, Hakansson, K, Timson, D.J, Wigley, D.B.
Deposit date:1998-11-16
Release date:1999-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the adenylation domain of an NAD+-dependent DNA ligase.
Structure Fold.Des., 7, 1999
3E1S
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BU of 3e1s by Molmil
Structure of an N-terminal truncation of Deinococcus radiodurans RecD2
Descriptor: Exodeoxyribonuclease V, subunit RecD
Authors:Saikrishnan, K, Griffiths, S.P, Cook, N, Court, R, Wigley, D.B.
Deposit date:2008-08-04
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:DNA binding to RecD: role of the 1B domain in SF1B helicase activity.
Embo J., 27, 2008
2PJR
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BU of 2pjr by Molmil
HELICASE PRODUCT COMPLEX
Descriptor: DNA (5'-D(*AP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*T)-3'), ...
Authors:Velankar, S.S, Soultanas, P, Dillingham, M.S, Subramanya, H.S, Wigley, D.B.
Deposit date:1999-03-12
Release date:1999-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.
Cell(Cambridge,Mass.), 97, 1999
3PJR
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BU of 3pjr by Molmil
HELICASE SUBSTRATE COMPLEX
Descriptor: 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Velankar, S.S, Soultanas, P, Dillingham, M.S, Subramanya, H.S, Wigley, D.B.
Deposit date:1999-03-12
Release date:1999-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism
Cell(Cambridge,Mass.), 97, 1999
2UUZ
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BU of 2uuz by Molmil
Orthorhombic crystal form of GamS from bacteriophage lambda.
Descriptor: HOST-NUCLEASE INHIBITOR PROTEIN GAM
Authors:Court, R.I, Cook, N, Saikrishnan, K, Wigley, D.B.
Deposit date:2007-03-08
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of Lambda-Gam Protein Suggests a Model for Recbcd Inhibition.
J.Mol.Biol., 371, 2007
3GPL
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BU of 3gpl by Molmil
Crystal structure of the ternary complex of RecD2 with DNA and ADPNP
Descriptor: 5'-D(*T*TP*TP*TP*TP*TP*TP*T)-3', Exodeoxyribonuclease V, subunit RecD, ...
Authors:Saikrishnan, K, Cook, N, Wigley, D.B.
Deposit date:2009-03-23
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic basis of 5'-3' translocation in SF1B helicases.
Cell(Cambridge,Mass.), 137, 2009
3GP8
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BU of 3gp8 by Molmil
Crystal structure of the binary complex of RecD2 with DNA
Descriptor: 5'-D(*TP*TP*TP*TP*TP*T*TP*TP*TP*TP*TP*TP*TP*T)-3', Exodeoxyribonuclease V, subunit RecD, ...
Authors:Saikrishnan, K, Cook, N, Wigley, D.B.
Deposit date:2009-03-23
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic basis of 5'-3' translocation in SF1B helicases.
Cell(Cambridge,Mass.), 137, 2009
3K70
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BU of 3k70 by Molmil
Crystal structure of the complete initiation complex of RecBCD
Descriptor: CALCIUM ION, DNA (46-MER), Exodeoxyribonuclease V alpha chain, ...
Authors:Saikrishnan, K, Wigley, D.B.
Deposit date:2009-10-11
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:DNA binding to RecD: role of the 1B domain in SF1B helicase activity.
Embo J., 27, 2008
2V1U
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BU of 2v1u by Molmil
STRUCTURE OF THE AEROPYRUM PERNIX ORC1 PROTEIN IN COMPLEX WITH DNA
Descriptor: 5'-D(*AP*CP*CP*CP*CP*TP*CP*CP*GP*TP *TP*TP*CP*CP*TP*GP*TP*GP*GP*AP*GP*A)-3', 5'-D(*TP*CP*TP*CP*CP*AP*CP*AP*GP*GP *AP*AP*AP*CP*GP*GP*AP*GP*GP*GP*GP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Gaudier, M, Schuwirth, B.S, Westcott, S.L, Wigley, D.B.
Deposit date:2007-05-30
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of DNA Replication Origin Recognition by an Orc Protein.
Science, 317, 2007
2UV1
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BU of 2uv1 by Molmil
Hexagonal crystal form of GamS from bacteriophage lambda.
Descriptor: HOST-NUCLEASE INHIBITOR PROTEIN GAM
Authors:Court, R.I, Cook, N, Saikrishnan, K, Wigley, D.B.
Deposit date:2007-03-08
Release date:2007-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of Lambda-Gam Protein Suggests a Model for Recbcd Inhibition.
J.Mol.Biol., 371, 2007
5LD2
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BU of 5ld2 by Molmil
Cryo-EM structure of RecBCD+DNA complex revealing activated nuclease domain
Descriptor: Fork-Hairpin DNA (70-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Wilkinson, M, Chaban, Y, Wigley, D.B.
Deposit date:2016-06-23
Release date:2016-10-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Mechanism for nuclease regulation in RecBCD.
Elife, 5, 2016
5MBV
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BU of 5mbv by Molmil
Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD.
Descriptor: Host-nuclease inhibitor protein gam, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ...
Authors:Wilkinson, M, Chaban, Y, Wigley, D.B.
Deposit date:2016-11-08
Release date:2017-01-11
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones.
Elife, 5, 2016
8B1T
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BU of 8b1t by Molmil
RecBCD-DNA in complex with the phage protein Abc2
Descriptor: Anti-RecBCD protein 2, DNA (70-MER), MAGNESIUM ION, ...
Authors:Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S.
Deposit date:2022-09-12
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub.
Elife, 11, 2022
8B1R
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BU of 8b1r by Molmil
RecBCD in complex with the phage protein gp5.9
Descriptor: MAGNESIUM ION, Probable RecBCD inhibitor gp5.9, RecBCD enzyme subunit RecB, ...
Authors:Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S.
Deposit date:2022-09-12
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub.
Elife, 11, 2022
8B1U
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BU of 8b1u by Molmil
RecBCD-DNA in complex with the phage protein Abc2 and host PpiB
Descriptor: Anti-RecBCD protein 2, DNA (70-MER), MAGNESIUM ION, ...
Authors:Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S.
Deposit date:2022-09-12
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub.
Elife, 11, 2022
1A0P
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BU of 1a0p by Molmil
SITE-SPECIFIC RECOMBINASE, XERD
Descriptor: SITE-SPECIFIC RECOMBINASE XERD
Authors:Subramanya, H.S, Arciszewska, L.K, Baker, R.A, Bird, L.E, Sherratt, D.J, Wigley, D.B.
Deposit date:1997-12-05
Release date:1998-03-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the site-specific recombinase, XerD.
EMBO J., 16, 1997
1A0I
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BU of 1a0i by Molmil
ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA LIGASE
Authors:Subramanya, H.S, Doherty, A.J, Ashford, S.R, Wigley, D.B.
Deposit date:1997-12-01
Release date:1998-03-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7.
Cell(Cambridge,Mass.), 85, 1996
6QXT
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BU of 6qxt by Molmil
Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-08
Release date:2019-05-08
Last modified:2019-07-24
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
6QY3
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BU of 6qy3 by Molmil
Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-08
Release date:2019-05-08
Last modified:2019-07-24
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
6QXF
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BU of 6qxf by Molmil
Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-07
Release date:2019-05-08
Last modified:2019-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
1CKO
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BU of 1cko by Molmil
STRUCTURE OF MRNA CAPPING ENZYME IN COMPLEX WITH THE CAP ANALOG GPPPG
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME, ZINC ION
Authors:Hakansson, K, Wigley, D.B.
Deposit date:1997-09-06
Release date:1998-01-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.
Proc.Natl.Acad.Sci.USA, 95, 1998
6FWR
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BU of 6fwr by Molmil
Structure of DinG in complex with ssDNA
Descriptor: ATP-dependent DNA helicase DinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), IRON/SULFUR CLUSTER
Authors:Cheng, K, Wigley, D.B.
Deposit date:2018-03-07
Release date:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA translocation mechanism of an XPD family helicase.
Elife, 7, 2018

 

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