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2O0R
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THE THREE-DIMENSIONAL STRUCTURE OF N-SUCCINYLDIAMINOPIMELATE AMINOTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Rv0858c (N-Succinyldiaminopimelate aminotransferase), CHLORIDE ION, GLYCEROL, ...
Authors:Weyand, S., Kefala, G., Weiss, M.S., TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-11-28
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Three-dimensional Structure of N-Succinyldiaminopimelate Aminotransferase from Mycobacterium tuberculosis
J.Mol.Biol., 367, 2007
2JLN
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER
Descriptor:MHP1, SODIUM ION, MERCURY (II) ION
Authors:Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, O., Krusong, K., Carpenter, E.P., Rutherford, N.G., Hadden, J.M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S.G., Hope, R.J., Norbertczak, H.T., Roach, P.C.J., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2008-09-11
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter.
Science, 322, 2008
2O0T
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THE THREE DIMENSIONAL STRUCTURE OF DIAMINOPIMELATE DECARBOXYLASE FROM MYCOBACTERIUM TUBERCULOSIS REVEALS A TETRAMERIC ENZYME ORGANISATION
Descriptor:Diaminopimelate decarboxylase, SULFATE ION
Authors:Weyand, S., Kefala, G., Weiss, M.S., TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-11-28
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The three-dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation.
J Struct Funct Genomics, 10, 2009
4D1A
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH INDOLYLMETHYL-HYDANTOIN
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione, SODIUM ION
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1C
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BROMOVINYLHYDANTOIN BOUND.
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5Z)-5-[(3-bromophenyl)methylidene]imidazolidine-2,4-dione, SODIUM ION
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1D
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER WITH THE INHIBITOR 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN.
Descriptor:HYDANTOIN TRANSPORT PROTEIN, 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN, 5-(2-NAPHTHYLMETHYL)-D-HYDANTOIN, ...
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
2X79
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INWARD FACING CONFORMATION OF MHP1
Descriptor:HYDANTOIN TRANSPORT PROTEIN
Authors:Shimamura, T., Weyand, S., Beckstein, O., Rutherford, N.G., Hadden, J.M., Sharples, D., Sansom, M.S.P., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2010-02-25
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1.
Science, 328, 2010
3RZE
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STRUCTURE OF THE HUMAN HISTAMINE H1 RECEPTOR IN COMPLEX WITH DOXEPIN
Descriptor:Histamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ...
Authors:Shimamura, T., Han, G.W., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Kobayashi, T., Stevens, R., Iwata, S., GPCR Network (GPCR)
Deposit date:2011-05-11
Release date:2011-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
3VG9
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 2.7 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
3VGA
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 3.1 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
4D1B
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5S)-5-benzylimidazolidine-2,4-dione, SODIUM ION
Authors:Brueckner, F., Geng, T., Weyand, S., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
3FSX
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STRUCTURE OF TETRAHYDRODIPICOLINATE N-SUCCINYLTRANSFERASE (RV1201C; DAPD) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Tetrahydrodipicolinate N-succinyltransferase, ACETIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Schuldt, L., Weyand, S., Kefala, G., Weiss, M.S.
Deposit date:2009-01-12
Release date:2009-06-23
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism.
J.Mol.Biol., 389, 2009
3FSY
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STRUCTURE OF TETRAHYDRODIPICOLINATE N-SUCCINYLTRANSFERASE (RV1201C;DAPD) IN COMPLEX WITH SUCCINYL-COA FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Tetrahydrodipicolinate N-succinyltransferase, SUCCINYL-COENZYME A, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Schuldt, L., Weyand, S., Kefala, G., Weiss, M.S.
Deposit date:2009-01-12
Release date:2009-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism.
J.Mol.Biol., 389, 2009
3AIB
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CRYSTAL STRUCTURE OF GLUCANSUCRASE
Descriptor:Glucosyltransferase-SI, CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Ito, K., Ito, S., Shimamura, T., Iwata, S.
Deposit date:2010-05-12
Release date:2011-03-23
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans.
J.Mol.Biol., 408, 2011
3AIC
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CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS
Descriptor:Glucosyltransferase-SI, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Ito, K., Ito, S., Shimamura, T., Iwata, S.
Deposit date:2010-05-12
Release date:2011-03-23
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans.
J.Mol.Biol., 408, 2011
3AIE
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CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS
Descriptor:Glucosyltransferase-SI, CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Ito, K., Ito, S., Shimamura, T., Iwata, S.
Deposit date:2010-05-12
Release date:2011-03-23
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans.
J.Mol.Biol., 408, 2011
5A16
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CRYSTAL STRUCTURE OF FAB4201 RAISED AGAINST HUMAN ERYTHROCYTE ANION EXCHANGER 1
Descriptor:FAB4201 HEAVY CHAIN
Authors:Arakawa, T., Kobayashi-Yugiri, T., Alguel, Y., Weyand, S., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A., Kobayashi, T., Hamasaki, N., Iwata, S.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Anion Exchanger Domain of Human Erythrocyte Band 3
Science, 350, 2015