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2ROV
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BU of 2rov by Molmil
The split PH domain of ROCK II
Descriptor: Rho-associated protein kinase 2
Authors:Wen, W, Zhang, M.
Deposit date:2008-04-25
Release date:2008-06-24
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The split PH domain of ROCK II
To be Published
2ROW
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BU of 2row by Molmil
The C1 domain of ROCK II
Descriptor: Rho-associated protein kinase 2, ZINC ION
Authors:Wen, W, Zhang, M.
Deposit date:2008-04-25
Release date:2008-06-24
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The C1 domain of ROCK II
To be Published
2FJL
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BU of 2fjl by Molmil
Solution Structure of the Split PH domain in Phospholipase C-gamma1
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
Authors:Wen, W, Zhang, M.
Deposit date:2006-01-03
Release date:2006-03-14
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural Characterization of the Split Pleckstrin Homology Domain in Phospholipase C-{gamma}1 and Its Interaction with TRPC3
J.Biol.Chem., 281, 2006
2FZ0
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BU of 2fz0 by Molmil
Identification of yeast R-SNARE Nyv1p as a novel longin domain protein
Descriptor: v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane; Nyv1p
Authors:Wen, W, Zhang, M.
Deposit date:2006-02-08
Release date:2006-03-07
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Identification of the Yeast R-SNARE Nyv1p as a Novel Longin Domain-containing Protein
Mol.Cell.Biol., 17, 2006
2KXS
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BU of 2kxs by Molmil
ZO1 ZU5 domain in complex with GRINL1A peptide
Descriptor: Tight junction protein ZO-1, LINKER, peptide of Myocardium-enriched Zo-associated protein
Authors:Wen, W, Zhang, M.
Deposit date:2010-05-12
Release date:2011-03-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
Embo J., 30, 2011
2KXR
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BU of 2kxr by Molmil
ZO1 ZU5 domain MC/AA mutation
Descriptor: Tight junction protein ZO-1
Authors:Wen, W, Zhang, M.
Deposit date:2010-05-12
Release date:2011-03-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
Embo J., 30, 2011
2RLO
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BU of 2rlo by Molmil
Split PH domain of PI3-kinase enhancer
Descriptor: Centaurin-gamma 1
Authors:Wen, W, Zhang, M.
Deposit date:2007-07-21
Release date:2008-04-29
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Split pleckstrin homology domain-mediated cytoplasmic-nuclear localization of PI3-kinase enhancer GTPase
J.Mol.Biol., 378, 2008
1Z87
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BU of 1z87 by Molmil
solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Descriptor: Alpha-1-syntrophin
Authors:Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
1Z86
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BU of 1z86 by Molmil
Solution structure of the PDZ domain of alpha-syntrophin
Descriptor: Alpha-1-syntrophin
Authors:Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
2ADZ
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BU of 2adz by Molmil
solution structure of the joined PH domain of alpha1-syntrophin
Descriptor: Alpha-1-syntrophin
Authors:Yan, J, Wen, W, Xu, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
Deposit date:2005-07-21
Release date:2006-01-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
2LA8
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BU of 2la8 by Molmil
Solution structure of INAD PDZ5 complexed with Kon-tiki peptide
Descriptor: Inactivation-no-after-potential D protein,kon-tiki peptide
Authors:Zhang, M, Wen, W.
Deposit date:2011-03-08
Release date:2011-11-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye
Cell(Cambridge,Mass.), 145, 2011
3RO3
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BU of 3ro3 by Molmil
crystal structure of LGN/mInscuteable complex
Descriptor: CHLORIDE ION, ETHANOL, G-protein-signaling modulator 2, ...
Authors:Zhu, J, Wen, W, Shang, Y, Wei, Z, Pan, Z, Wang, W, Zhang, M.
Deposit date:2011-04-25
Release date:2012-03-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
2M0Y
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BU of 2m0y by Molmil
Solution structure of the SH3 domain of DOCK180
Descriptor: Dedicator of cytokinesis protein 1
Authors:Liu, X, Wen, W.
Deposit date:2012-11-08
Release date:2012-12-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of DOCK180.
Proteins, 81, 2013
5CFF
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BU of 5cff by Molmil
Crystal structure of Miranda/Staufen dsRBD5 complex
Descriptor: Miranda, Staufen
Authors:Shan, Z, Wen, W.
Deposit date:2015-07-08
Release date:2015-10-21
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division
Nat Commun, 6, 2015
3UAT
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BU of 3uat by Molmil
Guanylate Kinase Domains of the MAGUK Family Scaffold Proteins as Specific Phospho-Protein Binding Modules
Descriptor: Disks large homolog 1, phosphor-LGN peptide
Authors:Shang, Y, Zhu, J, Wen, W, Zhang, M.
Deposit date:2011-10-22
Release date:2011-12-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules
Embo J., 2011
4G5S
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BU of 4g5s by Molmil
Structure of LGN GL3/Galphai3 complex
Descriptor: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
5J19
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BU of 5j19 by Molmil
phospho-Pon binding-induced Plk1 dimerization
Descriptor: GLYCEROL, Phosphorylated peptide from Partner of Numb, Serine/threonine-protein kinase PLK1
Authors:Zhu, K, Shan, Z, Zhang, L, Wen, W.
Deposit date:2016-03-29
Release date:2016-06-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
Structure, 24, 2016
5XMC
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BU of 5xmc by Molmil
Crystal structure of the auto-inhibited Nedd4 family E3 ligase Itch
Descriptor: E3 ubiquitin-protein ligase Itchy
Authors:Shan, Z, Wen, W.
Deposit date:2017-05-13
Release date:2017-08-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch
EMBO Rep., 18, 2017
5YQG
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BU of 5yqg by Molmil
The structure of 14-3-3 and pNumb peptide
Descriptor: 14-3-3 protein eta, Peptide from Protein numb homolog
Authors:Chen, X, Liu, Z, Wen, W.
Deposit date:2017-11-06
Release date:2018-02-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex.
J. Biol. Chem., 293, 2018
4G5O
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BU of 4g5o by Molmil
Structure of LGN GL4/Galphai3(Q147L) complex
Descriptor: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G2V
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BU of 4g2v by Molmil
Structure complex of LGN binding with FRMPD1
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, G-protein-signaling modulator 2, ...
Authors:Shang, Y, Pan, Z, Wen, W, Wang, W, Zhang, M.
Deposit date:2012-07-13
Release date:2013-01-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biochemical characterization of the interaction between LGN and Frmpd1
J.Mol.Biol., 425, 2013
4G5R
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BU of 4g5r by Molmil
Structure of LGN GL4/Galphai3 complex
Descriptor: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.481 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5Q
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BU of 4g5q by Molmil
Structure of LGN GL4/Galphai1 complex
Descriptor: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4JHR
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BU of 4jhr by Molmil
An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
Descriptor: G-protein-signaling modulator 2
Authors:Pan, Z, Zhu, J, Shang, Y, Wei, Z, Jia, M, Xia, C, Wen, W, Wang, W, Zhang, M.
Deposit date:2013-03-05
Release date:2013-06-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
Structure, 21, 2013
5YI8
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BU of 5yi8 by Molmil
Crystal structure of drosophila Numb PTB domain and Pon peptide complex
Descriptor: FORMIC ACID, Pon peptide from Partner of numb, Protein numb
Authors:Shan, Z, Wen, W.
Deposit date:2017-10-03
Release date:2018-04-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division.
Nat Commun, 9, 2018

 

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