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6O0H
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BU of 6o0h by Molmil
Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate
Authors:Wei, J, Tong, L.
Deposit date:2019-02-16
Release date:2019-04-17
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:An allosteric mechanism for potent inhibition of human ATP-citrate lyase.
Nature, 568, 2019
4DZD
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BU of 4dzd by Molmil
Crystal structure of the CRISPR-associated protein Cas6e from Escherichia coli str. K-12
Descriptor: GLYCEROL, Uncharacterized protein ygcH
Authors:Wei, J, Huang, G, Wang, Y, Gong, W.
Deposit date:2012-03-01
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal Structure of endoribonuclease Cas6e from Escherichia coli
To be Published
5CS4
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BU of 5cs4 by Molmil
Crystal structure of domains AC3-AC5 of yeast acetyl-CoA carboxylase
Descriptor: Acetyl-CoA carboxylase
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
5CS0
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BU of 5cs0 by Molmil
Crystal structure of domains AC1-AC2 of yeast acetyl-CoA carboxylase
Descriptor: Acetyl-CoA carboxylase
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
5CSK
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BU of 5csk by Molmil
Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated
Descriptor: Acetyl-CoA carboxylase
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
5CSL
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BU of 5csl by Molmil
Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Acetyl-CoA carboxylase, COENZYME A
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
5CSA
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BU of 5csa by Molmil
Crystal structure of domains BT-BCCP-AC1-AC5 of yeast acetyl-CoA carboxylase
Descriptor: Acetyl-CoA carboxylase
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
3JUI
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BU of 3jui by Molmil
Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
Descriptor: GLYCEROL, Translation initiation factor eIF-2B subunit epsilon
Authors:Wei, J, Xu, H, Zhang, C, Wang, M, Gao, F, Gong, W.
Deposit date:2009-09-15
Release date:2009-10-06
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
To be published
5TRC
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BU of 5trc by Molmil
Crystal structure of phosphorylated AC3-AC5 domains of yeast acetyl-CoA carboxylase
Descriptor: Acetyl-CoA carboxylase, CHLORIDE ION
Authors:Wei, J, Tong, L.
Deposit date:2016-10-26
Release date:2016-12-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation.
Cell Discov, 2, 2016
2K6S
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BU of 2k6s by Molmil
Structure of Rab11-FIP2 C-terminal Coiled-coil Domain
Descriptor: Rab11fip2 protein
Authors:Wei, J, Liu, Y, Baleja, J.D.
Deposit date:2008-07-18
Release date:2009-06-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Disorder and structure in the Rab11 binding domain of Rab11 family interacting protein 2.
Biochemistry, 48, 2009
7VYO
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BU of 7vyo by Molmil
The structure of GdmN
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-14
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZU
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BU of 7vzu by Molmil
The structure of GdmN Y82F mutant
Descriptor: 1,2-ETHANEDIOL, FE (III) ION, GdmN, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-16
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZY
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BU of 7vzy by Molmil
The structure of GdmN complex with AMP and 20-O-methyl-19-chloroproansamitocin
Descriptor: (5~{S},6~{E},8~{S},9~{S},12~{R},15~{E})-21-chloranyl-12,20-dimethoxy-6,8,16-trimethyl-5,9-bis(oxidanyl)-2-azabicyclo[16.3.1]docosa-1(21),6,15,18(22),19-pentaene-3,11-dione, 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-17
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VYJ
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BU of 7vyj by Molmil
The structure of GdmN in complex with carbamoyl adenylate intermediate
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, DI(HYDROXYETHYL)ETHER, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-14
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZZ
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BU of 7vzz by Molmil
The structure of GdmN in complex with the natural tetrahedral intermediate, carbamoyl adenylate, and 20-O-methyl-19-chloroproansamitocin
Descriptor: (5~{S},6~{E},8~{S},9~{S},12~{R},15~{E})-21-chloranyl-12,20-dimethoxy-6,8,16-trimethyl-5,9-bis(oxidanyl)-2-azabicyclo[16.3.1]docosa-1(21),6,15,18(22),19-pentaene-3,11-dione, 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-17
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VYP
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BU of 7vyp by Molmil
The structure of GdmN complex with the natural tetrahedral intermediate, carbamoylated derivative, and AMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, FE (III) ION, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-15
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VX0
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BU of 7vx0 by Molmil
The structure of GdmN complex with ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-12
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZQ
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BU of 7vzq by Molmil
The structure of GdmN V24Y/G157A/R158A/G188R mutant in complex with carbamoyl adenylate intermediate
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, CHLORIDE ION, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-16
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZN
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BU of 7vzn by Molmil
The structure of GdmN in complex with carbamoyl adenylate intermediate and 20-O-methyl-19-chloroproansamitocin
Descriptor: (5~{S},6~{E},8~{S},9~{S},12~{R},15~{E})-21-chloranyl-12,20-dimethoxy-6,8,16-trimethyl-5,9-bis(oxidanyl)-2-azabicyclo[16.3.1]docosa-1(21),6,15,18(22),19-pentaene-3,11-dione, 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-16
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
8E3Q
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BU of 8e3q by Molmil
CRYO-EM STRUCTURE OF the human MPSF
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, ZINC ION, ...
Authors:Gutierrez, P.A, Wei, J, Sun, Y, Tong, L.
Deposit date:2022-08-17
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
Rna, 28, 2022
8E3I
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BU of 8e3i by Molmil
CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*CP*AP*UP*UP*AP*AP*AP*CP*AP*AP*C)-3'), ...
Authors:Gutierrez, P.A, Wei, J, Sun, Y, Tong, L.
Deposit date:2022-08-17
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
Rna, 28, 2022
5T5H
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BU of 5t5h by Molmil
Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit
Descriptor: 40S ribosomal protein L14, 5.8S rRNA, 5S rRNA, ...
Authors:Liu, Z, Gutierrez-Vargas, C, Wei, J, Grassucci, R.A, Ramesh, M, Espina, N, Sun, M, Tutuncuoglu, B, Madison-Antenucci, S, Woolford Jr, J.L, Tong, L, Frank, J.
Deposit date:2016-08-31
Release date:2016-10-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HWL
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BU of 5hwl by Molmil
Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form
Descriptor: GLUTATHIONE, Glutathione S-transferase Mu 2, N,N'-(butane-1,4-diyl)bis{2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetamide}
Authors:Zhang, X, Wei, J, Wu, S, Zhang, H.P, Luo, M, Yang, X.L, Liao, F, Wang, D.Q.
Deposit date:2016-01-29
Release date:2017-11-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form
To Be Published
5IHW
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BU of 5ihw by Molmil
The crystal structure of SdrE from staphylococcus aureus
Descriptor: Serine-aspartate repeat-containing protein E
Authors:Zhang, S, Wei, J, Wu, S, Zhang, X, Luo, M, Wang, D.
Deposit date:2016-02-29
Release date:2017-03-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The crystal structure of SdrE from staphylococcus aureus
To Be Published
4FYP
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BU of 4fyp by Molmil
Crystal Structure of Plant Vegetative Storage Protein
Descriptor: MAGNESIUM ION, Vegetative storage protein 1
Authors:Chen, Y, Wei, J, Wang, M, Gong, W, Zhang, M.
Deposit date:2012-07-05
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of Arabidopsis VSP1 reveals the plant class C-like phosphatase structure of the DDDD superfamily of phosphohydrolases
Plos One, 7, 2012

 

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