Author results

2JTU
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NMR STRUCTURE OF IOTA-RXIA(38)
分子名称:I-superfamily conotoxin r11a
著者Wei, D., Norton, R.
登録日2007-08-06
公開日2008-08-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of iota-RXIA(38)
To be Published
3QXR
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CRYSTAL STRUCTURE OF THE BROMINATED CKIT-1 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
分子名称:5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*(BRU)P*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3', POTASSIUM ION, MAGNESIUM ION
著者Wei, D., Parkinson, G.N., Neidle, S.
登録日2011-03-02
公開日2012-01-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation.
Nucleic Acids Res., 40, 2012
4H29
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B-RAF DIMER DNA QUADRUPLEX
分子名称:DNA (5'-D(*GP*GP*GP*CP*GP*GP*GP*GP*AP*GP*GP*GP*GP*GP*AP*AP*GP*GP*GP*A)-3'), POTASSIUM ION
著者Wei, D., Parkinson, G., Neidle, S.
登録日2012-09-12
公開日2013-07-31
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Crystal Structure of a Promoter Sequence in the B-raf Gene Reveals an Intertwined Dimer Quadruplex.
J.Am.Chem.Soc., 135, 2013
4WO2
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CRYSTAL STRUCTURE OF HUMAN NATIVE CKIT PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
分子名称:DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION
著者wei, D., parkinson, g.n., neidle, s.
登録日2014-10-15
公開日2014-10-22
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献CRYSTAL STRUCTURE OF HUMAN NATIVE CKIT-1 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
TO BE PUBLISHED
4WO3
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THE SECOND C-KIT DNA QUADRUPLEX CRYSTAL STRUCTURE
分子名称:DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION
著者Wei, D., Neidle, S.
登録日2014-10-15
公開日2014-10-29
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献THE SECOND C-KIT1 DNA QUADRUPLEX CRYSTAL STRUCTURE
TO BE PUBLISHED
1A6X
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STRUCTURE OF THE APO-BIOTIN CARBOXYL CARRIER PROTEIN (APO-BCCP87) OF ESCHERICHIA COLI ACETYL-COA CARBOXYLASE, NMR, 49 STRUCTURES
分子名称:APO-BIOTIN CARBOXYL CARRIER PROTEIN OF ACETYL-COA CARBOXYLASE
著者Yao, X., Wei, D., Soden Junior, C., Summers, M.F., Beckett, D.
登録日1998-03-04
公開日1998-10-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the carboxy-terminal fragment of the apo-biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase.
Biochemistry, 36, 1997
2JRY
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STRUCTURE AND SODIUM CHANNEL ACTIVITY OF AN EXCITATORY I1-SUPERFAMILY CONOTOXIN
分子名称:I-superfamily conotoxin r11a
著者Buczek, O., Wei, D., Babon, J., Yang, X., Fiedler, B., Chen, P., Yoshikami, D., Olivera, B., Bulaj, G., Norton, R.
登録日2007-06-29
公開日2007-10-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Biochemistry, 46, 2007
1WM7
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SOLUTION STRUCTURE OF BMP01 FROM THE VENOM OF SCORPION BUTHUS MARTENSII KARSCH, 9 STRUCTURES
分子名称:Neurotoxin BmP01
著者Wu, G., Li, Y., Wei, D., He, F., Jiang, S., Hu, G., Wu, H., Chen, X.
登録日2004-07-05
公開日2004-07-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 276, 2000
3VZ0
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STRUCTURAL INSIGHTS INTO COFACTOR AND SUBSTRATE SELECTION BY GOX0499
分子名称:Putative NAD-dependent aldehyde dehydrogenase, NONAETHYLENE GLYCOL
著者Yuan, Y.A., Yuan, Z., Yin, B., Wei, D.
登録日2012-10-09
公開日2013-07-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
3VZ1
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND COFACTOR SELELCTION BY SP2771
分子名称:Succinate-semialdehyde dehydrogenase
著者Yuan, Y.A., Yuan, Z., Yin, B., Wei, D.
登録日2012-10-09
公開日2013-07-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
3VZ2
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND COFACTOR SELECTION BY SP2771
分子名称:Succinate-semialdehyde dehydrogenase
著者Yuan, Y.A., Yuan, Z., Yin, B., Wei, D.
登録日2012-10-09
公開日2013-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
3VZ3
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STRUCTURAL INSIGHTS INTO SUBSTRATE AND COFACTOR SELECTION BY SP2771
分子名称:Succinate-semialdehyde dehydrogenase, 4-oxobutanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Yuan, Y.A., Yuan, Z., Yin, B., Wei, D.
登録日2012-10-09
公開日2013-07-10
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
4EHR
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CRYSTAL STRUCTURE OF BCL-XL COMPLEX WITH 4-(5-BUTYL-3-(HYDROXYMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)-3-(3,4-DIHYDRO-2(1H)-ISOQUINOLINYLCARBONYL)-N-((2-(TRIMETHYLSILYL)ETHYL)SULFONYL)BENZAMIDE
分子名称:Bcl-2-like protein 1, 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide, IMIDAZOLE
著者Schroeder, G.M., Wei, D., Banfi, P., Cai, Z., Lippy, J., Menichincheri, M., Modugno, M., Naglich, J., Penhallow, B., Perez, H.L., Sack, J., Schmidt, R.J., Tebben, A., Yan, C., Zhang, L., Galvani, A., Lombardo, L.J., Borzilleri, R.M.
登録日2012-04-03
公開日2012-06-06
最終更新日2012-06-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists.
Bioorg.Med.Chem.Lett., 22, 2012
3U05
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CRYSTAL STRUCTURE OF DB1804-D(CGCGAATTCGCG)2 COMPLEX
分子名称:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 6-(1,4,5,6-tetrahydropyrimidin-2-yl)-2-[4'-(1,4,5,6-tetrahydropyrimidin-2-yl)biphenyl-4-yl]-1H-indole
著者Wei, D.G., Neidle, S.
登録日2011-09-28
公開日2012-09-12
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U08
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CRYSTAL STRUCTURE OF DB1963-D(CGCGAATTCGCG)2 COMPLEX AT 1.25 A RESOLUTION
分子名称:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 4'-(5-carbamimidoyl-1H-benzimidazol-2-yl)biphenyl-4-carboxamide, MAGNESIUM ION
著者Wei, D.G., Neidle, S.
登録日2011-09-28
公開日2012-09-12
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U0U
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CRYSTAL STRUCTURE OF THE DB1883-D(CGCGAATTCGCG)2 COMPLEX AT 1.24 A RESOLUTION
分子名称:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 2-(4'-carbamimidoylbiphenyl-4-yl)-1H-indole-6-carboximidamide, MAGNESIUM ION
著者Wei, D.G., Neidle, S.
登録日2011-09-29
公開日2012-09-12
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
3U2N
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CRYSTAL STRUCTURE OF DNA(CGCGAATTCGCG)2 AT 1.25 ANGSTROMS
分子名称:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
著者Wei, D.G., Neidle, S.
登録日2011-10-04
公開日2013-04-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135, 2013
2P4L
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STRUCTURE AND SODIUM CHANNEL ACTIVITY OF AN EXCITATORY I1-SUPERFAMILY CONOTOXIN
分子名称:I-superfamily conotoxin r11a
著者Buczek, O., Wei, D.X., Babon, J.J., Yang, X.D., Fiedler, B., Yoshikami, D., Olivera, B.M., Bulaj, G., Norton, R.S.
登録日2007-03-12
公開日2007-09-25
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure and Sodium Channel Activity of an Excitatory I(1)-Superfamily Conotoxin
Biochemistry, 46, 2007
5IP0
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PHA BINDING PROTEIN PHAP (PHASIN)
分子名称:PHA granule-associated protein, CADMIUM ION
著者Chen, G.Q., Wang, X.Q., Zhao, H.Y.
登録日2016-03-09
公開日2017-01-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights on PHA Binding Protein PhaP from Aeromonas hydrophila
Sci Rep, 6, 2016
6CEZ
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CRYSTAL STRUCTURE OF RABBIT ANTI-HIV-1 GP120 V2 FAB 16C2 IN COMPLEX WITH V2 PEPTIDE CONB
分子名称:Light chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, HIV-1 gp120 V2 Peptide Con B
著者Kong, X., Pan, R.
登録日2018-02-13
公開日2018-09-12
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha 4 beta 7.
PLoS Pathog., 14, 2018
3CE3
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CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH A PYRROLOPYRIDINEPYRIDONE BASED INHIBITOR
分子名称:Hepatocyte growth factor receptor, 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide
著者Sack, J.
登録日2008-02-28
公開日2008-08-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of pyrrolopyridine-pyridone based inhibitors of Met kinase: synthesis, X-ray crystallographic analysis, and biological activities.
J.Med.Chem., 51, 2008
3WJ7
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CRYSTAL STRUCTURE OF GOX2253
分子名称:Putative oxidoreductase, MERCURY (II) ION
著者Yuan, Y.A., Yin, B.
登録日2013-10-05
公開日2014-06-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into substrate and coenzyme preference by SDR family protein Gox2253 from Gluconobater oxydans.
Proteins, 2014
3AWD
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CRYSTAL STRUCTURE OF GOX2181
分子名称:Putative polyol dehydrogenase, MAGNESIUM ION, CADMIUM ION
著者Adam Yuan, Y., Yuan, Z.
登録日2011-03-18
公開日2012-02-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans.
Biochem.Biophys.Res.Commun., 415, 2011
3C1X
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CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH A PYRROLOTRIAZINE BASED INHIBITOR
分子名称:Hepatocyte growth factor receptor, N-{[4-({5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}oxy)-3-fluorophenyl]carbamoyl}-2-(4-fluorophenyl)acetamide
著者Sack, J.
登録日2008-01-24
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Identification of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of Met kinase.
Bioorg.Med.Chem.Lett., 18, 2008
3CTH
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CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH A AMINOPYRIDINE BASED INHIBITOR
分子名称:Hepatocyte growth factor receptor, N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide
著者Sack, J.
登録日2008-04-14
公開日2008-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors
Bioorg.Med.Chem.Lett., 18, 2008
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