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5C9V
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STRUCTURE OF HUMAN PARKIN G319A
Descriptor:E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ...
Authors:Wauer, T., Komander, D.
Deposit date:2015-06-29
Release date:2015-07-22
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015
4BM9
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STRUCTURE OF THE AUTOINHIBITED PARKIN CATALYTIC DOMAIN
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION, SULFATE ION, ...
Authors:Wauer, T., Komander, D.
Deposit date:2013-05-07
Release date:2013-06-12
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Human Parkin Ligase Domain in an Autoinhibited State.
Embo J., 32, 2013
4WZP
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SER65 PHOSPHORYLATED UBIQUITIN, MAJOR CONFORMATION
Descriptor:ubiquitin, SULFATE ION
Authors:Wauer, T., Wagstaff, J., Freund, S.M.V., Komander, D.
Deposit date:2014-11-20
Release date:2015-01-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
Embo J., 34, 2015
5CAW
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STRUCTURE OF PEDICULUS HUMANUS PARKIN BOUND TO PHOSPHO-UBIQUITIN
Descriptor:E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ...
Authors:Wauer, T., Komander, D.
Deposit date:2015-06-30
Release date:2015-07-22
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015
3ZNV
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CRYSTAL STRUCTURE OF THE OTU DOMAIN OF OTULIN AT 1.3 ANGSTROMS.
Descriptor:PROTEIN FAM105B, GLYCEROL, CALCIUM ION, ...
Authors:Keusekotten, K., Elliott, P.R., Glockner, L., Kulathu, Y., Wauer, T., Krappmann, D., Hofmann, K., Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNX
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CRYSTAL STRUCTURE OF THE OTU DOMAIN OF OTULIN D336A MUTANT
Descriptor:PROTEIN FAM105B, CALCIUM ION, CHLORIDE ION, ...
Authors:Keusekotten, K., Elliott, P.R., Glockner, L., Kulathu, Y., Wauer, T., Krappmann, D., Hofmann, K., Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNZ
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CRYSTAL STRUCTURE OF OTULIN OTU DOMAIN (C129A) IN COMPLEX WITH MET1- DI UBIQUITIN
Descriptor:PROTEIN FAM105B, POLYUBIQUITIN-C, SULFATE ION
Authors:Keusekotten, K., Elliott, P.R., Glockner, L., Kulathu, Y., Wauer, T., Krappmann, D., Hofmann, K., Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
4BOP
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STRUCTURE OF OTUD1 OTU DOMAIN
Descriptor:OTU DOMAIN-CONTAINING PROTEIN 1, PHOSPHATE ION
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOQ
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STRUCTURE OF OTUD2 OTU DOMAIN
Descriptor:UBIQUITIN THIOESTERASE OTU1, GLYCEROL
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOS
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STRUCTURE OF OTUD2 OTU DOMAIN IN COMPLEX WITH UBIQUITIN K11-LINKED PEPTIDE
Descriptor:UBIQUITIN THIOESTERASE OTU1, POLYUBIQUITIN-C, OTUD2, ...
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOU
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STRUCTURE OF OTUD3 OTU DOMAIN
Descriptor:OTU DOMAIN-CONTAINING PROTEIN 3
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOZ
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STRUCTURE OF OTUD2 OTU DOMAIN IN COMPLEX WITH K11-LINKED DI UBIQUITIN
Descriptor:UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C, GLYCEROL
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013