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1R4X
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BU of 1r4x by Molmil
Crystal Structure Analys of the Gamma-COPI Appendage domain
Descriptor: Coatomer gamma subunit, MAGNESIUM ION
Authors:Watson, P.J, Frigerio, G, Collins, B.M, Duden, R, Owen, D.J.
Deposit date:2003-10-09
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
4A69
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BU of 4a69 by Molmil
Structure of HDAC3 bound to corepressor and inositol tetraphosphate
Descriptor: ACETATE ION, D-MYO INOSITOL 1,4,5,6 TETRAKISPHOSPHATE, GLYCEROL, ...
Authors:Watson, P.J, Fairall, L, Santos, G.M, Schwabe, J.W.R.
Deposit date:2011-11-01
Release date:2012-01-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of Hdac3 Bound to Co-Repressor and Inositol Tetraphosphate.
Nature, 481, 2012
5ICN
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BU of 5icn by Molmil
HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4
Descriptor: GLY-ALA-6A0-ARG-HIS, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Millard, C.J, Robertson, N.S, Watson, P.J, Jameson, A.G, Schwabe, J.W.R.
Deposit date:2016-02-23
Release date:2016-05-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
2XTE
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BU of 2xte by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTC
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BU of 2xtc by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
1Z2X
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BU of 1z2x by Molmil
Crystal structure of mouse Vps29
Descriptor: Vacuolar protein sorting 29
Authors:Collins, B.M, Skinner, C.F, Watson, P.J, Seaman, M.N.J, Owen, D.J.
Deposit date:2005-03-10
Release date:2005-06-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
NAT.STRUCT.MOL.BIOL., 12, 2005
1Z2W
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BU of 1z2w by Molmil
Crystal structure of mouse Vps29 complexed with Mn2+
Descriptor: GLYCEROL, MANGANESE (II) ION, Vacuolar protein sorting 29
Authors:Collins, B.M, Skinner, C.F, Watson, P.J, Seaman, M.N.J, Owen, D.J.
Deposit date:2005-03-10
Release date:2005-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
NAT.STRUCT.MOL.BIOL., 12, 2005
1NAF
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BU of 1naf by Molmil
Crystal structure of the human GGA1 GAT domain
Descriptor: ADP-ribosylation factor binding protein GGA1
Authors:Collins, B.M, Watson, P.J, Owen, D.J.
Deposit date:2002-11-27
Release date:2003-03-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the GGA1-GAT Domain Reveals the Molecular Basis for ARF Binding and Membrane Association of GGAs
Dev.Cell, 4, 2003
4BKX
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BU of 4bkx by Molmil
The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex
Descriptor: ACETATE ION, HISTONE DEACETYLASE 1, METASTASIS-ASSOCIATED PROTEIN MTA1, ...
Authors:Millard, C.J, Watson, P.J, Celardo, I, Gordiyenko, Y, Cowley, S.M, Robinson, C.V, Fairall, L, Schwabe, J.W.R.
Deposit date:2013-04-30
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates.
Mol.Cell, 51, 2013
6G16
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BU of 6g16 by Molmil
Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange
Descriptor: Histone-binding protein RBBP4, Metastasis-associated protein MTA1
Authors:Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R.
Deposit date:2018-03-20
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
3U66
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BU of 3u66 by Molmil
Crystal structure of T6SS SciP/TssL from Escherichia Coli Enteroaggregative 042
Descriptor: GLYCEROL, Putative type VI secretion protein
Authors:Durand, E, Aschtgen, M.S, Zoued, A, Spinelli, S, Watson, P.J.H, Cambillau, C, Cascales, E.
Deposit date:2011-10-12
Release date:2012-03-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems.
J.Biol.Chem., 287, 2012
2MWI
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BU of 2mwi by Molmil
The structure of the carboxy-terminal domain of DNTTIP1
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1
Authors:Schwabe, J.W.R, Muskett, F.W, Itoh, T.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
1UTC
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BU of 1utc by Molmil
Clathrin terminal domain complexed with TLPWDLWTT
Descriptor: AMPHIPHYSIN, CLATHRIN HEAVY CHAIN
Authors:Miele, A.E, Evans, P.R, Owen, D.J.
Deposit date:2003-12-08
Release date:2004-02-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
2L5G
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BU of 2l5g by Molmil
Co-ordinates and 1H, 13C and 15N chemical shift assignments for the complex of GPS2 53-90 and SMRT 167-207
Descriptor: G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J, Yang, J, Neuhaus, D, Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
5FXY
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BU of 5fxy by Molmil
Structure of the human RBBP4:MTA1(464-546) complex
Descriptor: HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1
Authors:Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R.
Deposit date:2016-03-03
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
4D6K
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BU of 4d6k by Molmil
Structure of DNTTIP1 dimerisation domain.
Descriptor: DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1
Authors:Itoh, T, Fairall, L, Schwabe, J.W.R.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting.
Nucleic Acids Res., 43, 2015
6Z2K
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BU of 6z2k by Molmil
The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-05-16
Release date:2020-07-08
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
6Z2J
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BU of 6z2j by Molmil
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-05-16
Release date:2020-07-08
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020

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