Author results

1AW5
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5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:5-AMINOLEVULINATE DEHYDRATASE, ZINC ION
Authors:Erskine, P.T., Cooper, J.B., Wood, S.P.
Deposit date:1997-10-09
Release date:1998-10-21
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase.
Nat.Struct.Biol., 4, 1997
1B4E
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X-RAY STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE COMPLEXED WITH THE INHIBITOR LEVULINIC ACID
Descriptor:PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), SULFATE ION, ZINC ION, ...
Authors:Erskine, P.T., Cooper, J.B., Lewis, G., Spencer, P., Wood, S.P., Shoolingin-Jordan, P.M.
Deposit date:1998-12-19
Release date:1999-12-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.
Biochemistry, 38, 1999
1CBF
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THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF
Descriptor:COBALT-PRECORRIN-4 TRANSMETHYLASE, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Schubert, H.L., Raux, E., Woodcock, S.C., Wilson, K.S., Warren, M.J.
Deposit date:1998-05-01
Release date:1999-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase.
Nat.Struct.Biol., 5, 1998
1EB3
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 4,7-DIOXOSEBACIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2001-07-18
Release date:2001-08-02
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
1GJP
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-OXOSEBACIC ACID
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 4-OXODECANEDIOIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2001-08-01
Release date:2001-08-02
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
1H7N
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-10
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7O
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, DELTA-AMINO VALERIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-10
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7P
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-KETO-5-AMINO-HEXANOIC (KAH) AT 1.64 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 5-AMINO-4-HYDROXYHEXANOIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-13
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7R
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH SUCCINYLACETONE AT 2.0 A RESOLUTION.
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 4,6-DIOXOHEPTANOIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-12
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1KYQ
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MET8P: A BIFUNCTIONAL NAD-DEPENDENT DEHYDROGENASE AND FERROCHELATASE INVOLVED IN SIROHEME SYNTHESIS.
Descriptor:Siroheme biosynthesis protein MET8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Schubert, H.L., Raux, E., Brindley, A.A., Wilson, K.S., Hill, C.P., Warren, M.J.
Deposit date:2002-02-05
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase.
EMBO J., 21, 2002
1OHL
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ZINC ION, BETA-MERCAPTOETHANOL, ...
Authors:Erskine, P.T., Coates, L., Butler, D., Youell, J.H., Brindley, A.A., Wood, S.P., Warren, M.J., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2003-05-27
Release date:2003-06-02
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase
Biochem.J., 373, 2003
1PDA
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STRUCTURE OF PORPHOBILINOGEN DEAMINASE REVEALS A FLEXIBLE MULTIDOMAIN POLYMERASE WITH A SINGLE CATALYTIC SITE
Descriptor:PORPHOBILINOGEN DEAMINASE, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID
Authors:Louie, G.V., Brownlie, P.D., Lambert, R., Cooper, J.B., Blundell, T.L., Wood, S.P., Warren, M.J., Woodcock, S.C., Jordan, P.M.
Deposit date:1992-11-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site.
Nature, 359, 1992
1PJQ
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STRUCTURE AND FUNCTION OF CYSG, THE MULTIFUNCTIONAL METHYLTRANSFERASE/DEHYDROGENASE/FERROCHELATASE FOR SIROHEME SYNTHESIS
Descriptor:Siroheme synthase, ACETATE ION, TRIETHYLENE GLYCOL, ...
Authors:Stroupe, M.E., Leech, H.K., Daniels, D.S., Warren, M.J., Getzoff, E.D.
Deposit date:2003-06-03
Release date:2003-12-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis.
Nat.Struct.Biol., 10, 2003
1PJS
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THE CO-CRYSTAL STRUCTURE OF CYSG, THE MULTIFUNCTIONAL METHYLTRANSFERASE/DEHYDROGENASE/FERROCHELATASE FOR SIROHEME SYNTHESIS, IN COMPLEX WITH IT NAD COFACTOR
Descriptor:Siroheme synthase, S-ADENOSYL-L-HOMOCYSTEINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Stroupe, M.E., Leech, H.K., Daniels, D.S., Warren, M.J., Getzoff, E.D.
Deposit date:2003-06-03
Release date:2003-12-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis.
Nat.Struct.Biol., 10, 2003
1PJT
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THE STRUCTURE OF THE SER128ALA POINT-MUTANT VARIANT OF CYSG, THE MULTIFUNCTIONAL METHYLTRANSFERASE/DEHYDROGENASE/FERROCHELATASE FOR SIROHEME SYNTHESIS
Descriptor:Siroheme synthase, S-ADENOSYL-L-HOMOCYSTEINE, PHOSPHATE ION
Authors:Stroupe, M.E., Leech, H.K., Daniels, D.S., Warren, M.J., Getzoff, E.D.
Deposit date:2003-06-03
Release date:2003-12-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis.
Nat.Struct.Biol., 10, 2003
1QGO
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ANAEROBIC COBALT CHELATASE IN COBALAMIN BIOSYNTHESIS FROM SALMONELLA TYPHIMURIUM
Descriptor:ANAEROBIC COBALAMIN BIOSYNTHETIC COBALT CHELATASE, SULFATE ION
Authors:Schubert, H.L., Raux, E., Warren, M.J., Wilson, K.S.
Deposit date:1999-05-03
Release date:1999-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Common chelatase design in the branched tetrapyrrole pathways of heme and anaerobic cobalamin synthesis.
Biochemistry, 38, 1999
1QML
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HG COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, MERCURY (II) ION
Authors:Erskine, P.T., Senior, N., Warren, M.J., Wood, S.P., Cooper, J.B.
Deposit date:1999-10-02
Release date:2000-10-06
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites
Acta Crystallogr.,Sect.D, 56, 2000
1QNV
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE LEAD (PB) COMPLEX
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, LEAD (II) ION
Authors:Erskine, P.T., Senior, N.M., Warren, M.J., Wood, S.P., Cooper, J.B.
Deposit date:1999-10-21
Release date:2000-10-19
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites
Acta Crystallogr.,Sect.D, 56, 2000
1S4D
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CRYSTAL STRUCTURE ANALYSIS OF THE S-ADENOSYL-L-METHIONINE DEPENDENT UROPORPHYRINOGEN-III C-METHYLTRANSFERASE SUMT
Descriptor:Uroporphyrin-III C-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL
Authors:Vevodova, J., Graham, R.M., Raux, E., Schubert, H.L., Roper, D.I., Brindley, A.A., Scott, A.I., Roessner, C.A., Stamford, N.P.J., Stroupe, M.E., Getzoff, E.D., Warren, M.J., Wilson, K.S.
Deposit date:2004-01-16
Release date:2004-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis
J.Mol.Biol., 344, 2004
1W31
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 5-HYDROXYLAEVULINIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2004-07-11
Release date:2005-08-23
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1YLV
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID
Descriptor:PROTEIN (5-AMINOLAEVULINIC ACID DEHYDRATASE), ZINC ION, LAEVULINIC ACID
Authors:Erskine, P.T., Newbold, R., Roper, J., Coker, A., Warren, M.J., Shoolingin-Jordan, P.M., Wood, S.P., Cooper, J.B.
Deposit date:1999-02-22
Release date:2000-02-23
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid.
Protein Sci., 8, 1999
2CBF
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THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF, FROM BACILLUS MEGATERIUM, WITH THE HIS-TAG CLEAVED OFF
Descriptor:COBALT-PRECORRIN-4 TRANSMETHYLASE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Schubert, H.L., Raux, E., Woodcock, S.C., Warren, M.J., Wilson, K.S.
Deposit date:1998-05-01
Release date:1999-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase.
Nat.Struct.Biol., 5, 1998
2DJ5
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CRYSTAL STRUCTURE OF THE VITAMIN B12 BIOSYNTHETIC COBALTOCHELATASE, CBIXS, FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Sirohydrochlorin cobaltochelatase, PHOSPHATE ION, GLYCEROL
Authors:Yin, J., Cherney, M.M., James, M.N.G.
Deposit date:2006-03-31
Release date:2006-09-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of the Vitamin B(12) Biosynthetic Cobaltochelatase, CbiX (S), from Archaeoglobus Fulgidus
J.STRUCT.FUNCT.GENOM., 7, 2006
2QBU
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CRYSTAL STRUCTURE OF METHANOTHERMOBACTER THERMAUTOTROPHICUS CBIL
Descriptor:Precorrin-2 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Frank, S., Warren, M.J., Pickersgill, R.W.
Deposit date:2007-06-18
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus.
J.Biol.Chem., 282, 2007
2W6K
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THE CRYSTAL STRUCTURE AT 1.7 A RESOLUTION OF COBE, A PROTEIN FROM THE COBALAMIN (VITAMIN B12) BIOSYNTHETIC PATHWAY
Descriptor:COBE, SULFATE ION, GLYCEROL
Authors:Vevodova, J., Smith, D., McGoldrick, H., Deery, E., Murzin, A.G., Warren, M.J., Wilson, K.S.
Deposit date:2008-12-18
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
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