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3W4K
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BU of 3w4k by Molmil
Crystal Structure of human DAAO in complex with coumpound 13
Descriptor: 3-hydroxy-6-(2-phenylethyl)pyridazin-4(1H)-one, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M.
Deposit date:2013-01-09
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors.
J.Med.Chem., 56, 2013
3W4J
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BU of 3w4j by Molmil
Crystal Structure of human DAAO in complex with coumpound 12
Descriptor: 3-hydroxy-5-(2-phenylethyl)pyridin-2(1H)-one, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M.
Deposit date:2013-01-09
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors.
J.Med.Chem., 56, 2013
3W4I
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BU of 3w4i by Molmil
Crystal Structure of human DAAO in complex with coumpound 8
Descriptor: D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, pyridine-2,3-diol
Authors:Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M.
Deposit date:2013-01-09
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors.
J.Med.Chem., 56, 2013
1WOK
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BU of 1wok by Molmil
Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor
Descriptor: 3-(4-CHLOROPHENYL)QUINOXALINE-5-CARBOXAMIDE, Poly [ADP-ribose] polymerase-1
Authors:Iwashita, A, Hattori, K, Yamamoto, H, Ishida, J, Kido, Y, Kamijo, K, Murano, K, Miyake, H, Kinoshita, T, Warizaya, M, Ohkubo, M, Matsuoka, N, Mutoh, S.
Deposit date:2004-08-20
Release date:2005-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors.
Febs Lett., 579, 2005
2CV3
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BU of 2cv3 by Molmil
Crystal structure of porcine pancreatic elastase complexed with a macroclyclic peptide inhibitor
Descriptor: Elastase 1, Inhibitor FR901451
Authors:Kinoshita, T, Tada, T, Kitatani, T.
Deposit date:2005-05-31
Release date:2006-05-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the complex of porcine pancreatic elastase with a trimacrocyclic peptide inhibitor FR901451
Acta Crystallogr.,Sect.F, 61, 2005
1WZY
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BU of 1wzy by Molmil
Crystal structure of human ERK2 complexed with a pyrazolopyridazine derivative
Descriptor: 1-ALLYL-5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, Mitogen-activated protein kinase 1
Authors:Kinoshita, T.
Deposit date:2005-03-10
Release date:2005-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human ERK2 complexed with a pyrazolo[3,4-c]pyridazine derivative
Bioorg.Med.Chem.Lett., 16, 2006
3W55
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BU of 3w55 by Molmil
The structure of ERK2 in complex with FR148083
Descriptor: (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Mitogen-activated protein kinase 1
Authors:Ohori, M, Kinoshita, T.
Deposit date:2013-01-21
Release date:2013-02-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Role of a cysteine residue in the active site of ERK and the MAPKK family
Biochem.Biophys.Res.Commun., 353, 2007
1VFL
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BU of 1vfl by Molmil
Adenosine deaminase
Descriptor: Adenosine deaminase, ZINC ION
Authors:Kinoshita, T.
Deposit date:2004-04-16
Release date:2005-08-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Compound Recognition by Adenosine Deaminase
Biochemistry, 44, 2005
1WXY
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BU of 1wxy by Molmil
Crystal structure of adenosine deaminase ligated with a potent inhibitor
Descriptor: Adenosine deaminase, N-[4,5-BIS(4-HYDROXYPHENYL)-1,3-THIAZOL-2-YL]HEXANAMIDE, ZINC ION
Authors:Kinoshita, T.
Deposit date:2005-02-02
Release date:2005-08-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Compound Recognition by Adenosine Deaminase
Biochemistry, 44, 2005
1UK0
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BU of 1uk0 by Molmil
Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor
Descriptor: 2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1
Authors:Kinoshita, T.
Deposit date:2003-08-13
Release date:2004-01-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase.
Febs Lett., 556, 2004
1WYI
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BU of 1wyi by Molmil
human triosephosphate isomerase of new crystal form
Descriptor: Triosephosphate isomerase
Authors:Kinoshita, T.
Deposit date:2005-02-14
Release date:2005-04-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method.
Acta Crystallogr.,Sect.F, 61, 2005

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