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6OAL
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BU of 6oal by Molmil
Structure of human PARG complexed with JA2120
Descriptor: 1,3-dimethyl-8-{[2-(morpholin-4-yl)ethyl]sulfanyl}-3,7-dihydro-1H-purine-2,6-dione, Poly(ADP-ribose) glycohydrolase
Authors:Brosey, C.A, Ahmed, Z, Warden, S, Tainer, J.A.
Deposit date:2019-03-16
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death.
Nat Commun, 10, 2019
6OAK
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BU of 6oak by Molmil
Structure of human PARG complexed with JA2131
Descriptor: (8S)-1,3-dimethyl-8-{[2-(morpholin-4-yl)ethyl]sulfanyl}-6-sulfanylidene-1,3,6,7,8,9-hexahydro-2H-purin-2-one, Poly(ADP-ribose) glycohydrolase
Authors:Brosey, C.A, Ahmed, Z, Warden, S, Tainer, J.A.
Deposit date:2019-03-16
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death.
Nat Commun, 10, 2019

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