3DBQ | | CRYSTAL STRUCTURE OF TTK KINASE DOMAIN | | Descriptor: | Dual specificity protein kinase TTK | | Authors: | Wang, W., Yang, Y.T., Gao, Y.F., Zhu, S.C., Wang, F., Old, W., Xu, Q.B., Resing, K., Ahn, N., Lei, M., Liu, X.D. | | Deposit date: | 2008-06-02 | | Release date: | 2009-02-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and Mechanistic Insights into Mps1 Kinase Activation
J.CELL.MOL.MED., 13, 2008
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3VPV | |
4EB3 | | CRYSTAL STRUCTURE OF ISPH IN COMPLEX WITH ISO-HMBPP | | Descriptor: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, 3-(hydroxymethyl)but-3-en-1-yl trihydrogen diphosphate | | Authors: | Wang, W., Wang, K., Span, I., Bacher, A., Groll, M., Oldfield, E. | | Deposit date: | 2012-03-23 | | Release date: | 2013-02-06 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation.
J.Am.Chem.Soc., 134, 2012
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5W4U | | POL II ELONGATION COMPLEX WITH AN N6-METHYLADENINE-CONTAINING TEMPLATE | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Wang, W., Wang, D. | | Deposit date: | 2017-06-13 | | Release date: | 2018-06-20 | | Last modified: | 2019-07-03 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
J.Am.Chem.Soc., 139, 2017
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5W51 | |
5XET | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE BOUND BY METHIONYL-ADENYLATE (MET-AMP) | | Descriptor: | Methionine--tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, 1,2-ETHANEDIOL, ... | | Authors: | Wang, W., Qin, B., Wojdyla, J.A., Wang, M., Gao, X., Cui, S. | | Deposit date: | 2017-04-06 | | Release date: | 2018-07-11 | | Last modified: | 2018-08-01 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism.
IUCrJ, 5, 2018
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5XGQ | |
5Z1Q | | CRYSTAL STRUCTURES OF THE TRIMERIC N-TERMINAL DOMAIN OF CILIATE EUPLOTES OCTOCARINATUS CENTRIN | | Descriptor: | Centrin protein, CALCIUM ION, CHLORIDE ION | | Authors: | Wang, W., Zhao, Y., Yang, B., Wang, H. | | Deposit date: | 2017-12-27 | | Release date: | 2018-04-25 | | Last modified: | 2018-06-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions
Protein Sci., 27, 2018
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6BLO | | POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I+1 POSITION | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Wang, W., Wang, D. | | Deposit date: | 2017-11-10 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (3.401 Å) | | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BLP | | POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I+1 POSITION, SOAKING AMPCPP | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Wang, W., Wang, D. | | Deposit date: | 2017-11-11 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (3.203 Å) | | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BM2 | | POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I-1 POSITION | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Wang, W., Wang, D. | | Deposit date: | 2017-11-13 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (3.403 Å) | | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BM4 | | POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I-1 POSITION,SOAKING UMPNPP | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Wang, W., Wang, D. | | Deposit date: | 2017-11-13 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (2.951 Å) | | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BQF | | POL II ELONGATION COMPLEX WITH 'DT-AP' AT I+1, I-1 POSITION | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Wang, W., Wang, D. | | Deposit date: | 2017-11-27 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1GSO | |
2VV5 | | THE OPEN STRUCTURE OF MSCS | | Descriptor: | SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL | | Authors: | Wang, W., Dong, C., Johnson, K.A., Naismith, J.H. | | Deposit date: | 2008-06-03 | | Release date: | 2008-08-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The Structure of an Open Form of an E. Coli Mechanosensitive Channel at 3.45 A Resolution.
Science, 321, 2008
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4DQI | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND DCTP (PAIRED WITH DG OF TEMPLATE) | | Descriptor: | DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*C*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-15 | | Release date: | 2012-06-06 | | Last modified: | 2012-09-05 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DQP | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND DDCTP (PAIRED WITH DG OF TEMPLATE) | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*C*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-16 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DQQ | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MG2+ | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-16 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.595 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DQR | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MN2+ | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-16 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DQS | | BINARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT AND DUPLEX DNA WITH RC IN PRIMER TERMINUS PAIRED WITH DG OF TEMPLATE | | Descriptor: | DNA polymerase, DNA/RNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-R(P*C)-3'), DNA (5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-16 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DS4 | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND RCTP IN PRESENCE OF MN2+ | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-17 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.681 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DS5 | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND RCTP IN PRESENCE OF MG2+ | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*C)-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-17 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DSE | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT F710Y, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MG2+ | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-18 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4DSF | | TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT F710Y, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MN2+ | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-02-18 | | Release date: | 2012-06-06 | | Last modified: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.661 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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4E0D | | BINARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A AND DUPLEX DNA | | Descriptor: | DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | Authors: | Wang, W., Beese, L.S. | | Deposit date: | 2012-03-02 | | Release date: | 2012-06-06 | | Last modified: | 2012-09-05 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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