Author results

4AOJ
  • Download 4aoj
  • View 4aoj
Molmil generated image of 4aoj
HUMAN TRKA IN COMPLEX WITH THE INHIBITOR AZ-23
Descriptor:HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, ZINC ION
Authors:Wang, T., Lamb, M.L., Block, M.H., Davies, A.M., Han, Y., Hoffmann, E., Ioannidis, S., Josey, J.A., Liu, Z., Lyne, P.D., MacIntyre, T., Mohr, P.J., Omer, C.A., Sjogren, T., Thress, K., Wang, B., Wang, H., Yu, D., Zhang, H.
Deposit date:2012-03-28
Release date:2012-08-15
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors
Acs Med.Chem.Lett., 3, 2012
4FZX
  • Download 4fzx
  • View 4fzx
Molmil generated image of 4fzx
EXONUCLEASE X IN COMPLEX WITH 3' OVERHANGING DUPLEX DNA
Descriptor:DNA (5'-D(P*GP*TP*CP*AP*TP*TP*GP*TP*GP*GP*AP*TP*CP*CP*GP*AP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*CP*CP*AP*CP*AP*AP*TP*GP*AP*CP*CP*T)-3'), Exodeoxyribonuclease 10, ...
Authors:Wang, T., Sun, H., Cheng, F., Bi, L., Jiang, T.
Deposit date:2012-07-08
Release date:2013-07-03
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
4FZY
  • Download 4fzy
  • View 4fzy
Molmil generated image of 4fzy
EXONUCLEASE X IN COMPLEX WITH 12BP BLUNT-ENDED DSDNA
Descriptor:DNA (5'-D(*TP*GP*TP*AP*GP*AP*TP*TP*CP*GP*AP*G)-3'), Exodeoxyribonuclease 10, DNA (5'-D(P*CP*TP*CP*GP*AP*AP*TP*CP*TP*AP*CP*A)-3'), ...
Authors:Wang, T., Sun, H., Cheng, F., Bi, L., Jiang, T.
Deposit date:2012-07-08
Release date:2013-07-03
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
4FZZ
  • Download 4fzz
  • View 4fzz
Molmil generated image of 4fzz
EXONUCLEASE X IN COMPLEX WITH 5' OVERHANGING DUPLEX DNA
Descriptor:DNA (5'-D(*GP*TP*CP*AP*TP*TP*GP*TP*GP*GP*AP*TP*CP*CP*GP*AP*G)-3'), Exodeoxyribonuclease 10, SODIUM ION
Authors:Wang, T., Sun, H., Cheng, F., Bi, L., Jiang, T.
Deposit date:2012-07-08
Release date:2013-07-03
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
4ZS2
  • Download 4zs2
  • View 4zs2
Molmil generated image of 4zs2
STRUCTURAL COMPLEX OF FTO/FLUORESCEIN
Descriptor:Alpha-ketoglutarate-dependent dioxygenase FTO, 2-OXOGLUTARIC ACID, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, ...
Authors:Wang, T., Hong, T., Huang, Y., Yang, C.G., Zhou, X.
Deposit date:2015-05-13
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
4ZS3
  • Download 4zs3
  • View 4zs3
Molmil generated image of 4zs3
STRUCTURAL COMPLEX OF 5-AMINOFLUORESCEIN BOUND TO THE FTO PROTEIN
Descriptor:Alpha-ketoglutarate-dependent dioxygenase FTO, 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, ...
Authors:Wang, T., Hong, T., Huang, Y., Yang, C.G., Zhou, X.
Deposit date:2015-05-13
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
1ZMF
  • Download 1zmf
  • View 1zmf
Molmil generated image of 1zmf
C DOMAIN OF HUMAN CYCLOPHILIN-33(HCYP33)
Descriptor:Peptidyl-prolyl cis-trans isomerase E
Authors:Wang, T., Yun, C.-H., Gu, S.-Y., Chang, W.-R., Liang, D.-C.
Deposit date:2005-05-10
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:1.88A crystal structure of the C domain of hCyP33: A novel domain of peptidyl-prolyl cis-trans isomerase
Biochem.Biophys.Res.Commun., 333, 2005
2H3B
  • Download 2h3b
  • View 2h3b
Molmil generated image of 2h3b
CRYSTAL STRUCTURE OF MOUSE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE/VISFATIN/PRE-B CELL COLONY ENHANCING FACTOR 1
Descriptor:Nicotinamide phosphoribosyltransferase, SULFATE ION
Authors:Wang, T., Zhang, X., Bheda, P., Revollo, J.R., Imai, S.I., Wolberger, C.
Deposit date:2006-05-22
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006
2H3D
  • Download 2h3d
  • View 2h3d
Molmil generated image of 2h3d
CRYSTAL STRUCTURE OF MOUSE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE/VISFATIN/PRE-B CELL COLONY ENHANCING FACTOR IN COMPLEX WITH NICOTINAMIDE MONONULEOTIDE
Descriptor:Nicotinamide phosphoribosyltransferase, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
Authors:Wang, T., Zhang, X., Bheda, P., Revollo, J.R., Imai, S.I., Wolberger, C.
Deposit date:2006-05-22
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006
2L7Y
  • Download 2l7y
  • View 2l7y
Molmil generated image of 2l7y
SOLUTION STRUCTURE OF A PUTATIVE SURFACE PROTEIN
Descriptor:Putative endo-beta-N-acetylglucosaminidase
Authors:Wang, T., Yuan, G., Zhang, J., Tu, X.
Deposit date:2010-12-27
Release date:2012-02-29
Last modified:2012-11-21
Method:SOLUTION NMR
Cite:1H and 15N Assigned Chemical Shifts for a putative surface protein
To be Published
2LI6
  • Download 2li6
  • View 2li6
Molmil generated image of 2li6
1H, 13C, AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR YEAST PROTEIN
Descriptor:SWI/SNF chromatin-remodeling complex subunit SWI1
Authors:Wang, T., Zhang, J., Tu, X.
Deposit date:2011-08-24
Release date:2012-04-25
Method:SOLUTION NMR
Cite:Solution structure of SWI1 ARID domain from Saccharomyces cerevisiae and its non-specific binding to DNA
Proteins, 2012
3M91
  • Download 3m91
  • View 3m91
Molmil generated image of 3m91
CRYSTAL STRUCTURE OF THE PROKARYOTIC UBIQUITIN-LIKE PROTEIN (PUP) COMPLEXED WITH THE AMINO TERMINAL COILED COIL OF THE MYCOBACTERIUM TUBERCULOSIS PROTEASOMAL ATPASE MPA
Descriptor:Proteasome-associated ATPase, Prokaryotic ubiquitin-like protein pup
Authors:Wang, T., Li, H.
Deposit date:2010-03-19
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
3NAO
  • Download 3nao
  • View 3nao
Molmil generated image of 3nao
A DNA CRYSTAL DESIGNED TO CONTAIN TWO MOLECULES PER ASYMMETRIC UNIT CELL
Descriptor:DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), DNA (5'-D(P*GP*GP*CP*TP*GP*C)-3'), ...
Authors:Wang, T., Sha, R., Birktoft, J.J., Zheng, J., Mao, M., Seeman, N.C.
Deposit date:2010-06-02
Release date:2011-11-30
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (5.03 Å)
Cite:A DNA crystal designed to contain two molecules per asymmetric unit.
J.Am.Chem.Soc., 132, 2010
4EEQ
  • Download 4eeq
  • View 4eeq
Molmil generated image of 4eeq
CRYSTAL STRUCTURE OF E. FAECALIS DNA LIGASE WITH INHIBITOR
Descriptor:DNA ligase, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ...
Authors:Wang, T., Charifson, P., Wei, Y.
Deposit date:2012-03-28
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, Synthesis and Activity Evaluation of Potent NAD+ DNA Ligase Inhibitors as Potential Antibacterial Agents.
To be Published
4FPD
  • Download 4fpd
  • View 4fpd
Molmil generated image of 4fpd
DEPROTONATION OF D96 IN BACTERIORHODOPSIN OPENS THE PROTON UPTAKE PATHWAY
Descriptor:Bacteriorhodopsin, RETINAL, CHLORIDE ION, ...
Authors:Wang, T., Sessions, A.O., Lunde, C.S., Rouani, S., Glaeser, R.M., Facciotti, M.T., Duan, Y.
Deposit date:2012-06-22
Release date:2013-02-27
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Deprotonation of d96 in bacteriorhodopsin opens the proton uptake pathway.
Structure, 21, 2013
3WA5
  • Download 3wa5
  • View 3wa5
Molmil generated image of 3wa5
CRYSTAL STRUCTURE OF TYPE VI PEPTIDOGLYCAN MURAMIDASE EFFECTOR TSE3 IN COMPLEX WITH ITS COGNATE IMMUNITY PROTEIN TSI3
Descriptor:Type VI secretion exported 3, Tse3-specific immunity protein, 1,2-ETHANEDIOL, ...
Authors:Ding, J., Wang, T., Liu, W., Wang, D.C.
Deposit date:2013-04-26
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Complex structure of type VI peptidoglycan muramidase effector and a cognate immunity protein
Acta Crystallogr.,Sect.D, 69, 2013
4LUQ
  • Download 4luq
  • View 4luq
Molmil generated image of 4luq
CRYSTAL STRUCTURE OF VIRULENCE EFFECTOR TSE3 IN COMPLEX WITH NEUTRALIZER TSI3
Descriptor:Uncharacterized protein, CALCIUM ION
Authors:Wang, T., Li, L., Zhang, W.
Deposit date:2013-07-25
Release date:2013-09-18
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural Insights on the Bacteriolytic and Self-protection Mechanism of Muramidase Effector Tse3 in Pseudomonas aeruginosa
J.Biol.Chem., 288, 2013
2MUZ
  • Download 2muz
  • View 2muz
Molmil generated image of 2muz
SSNMR STRUCTURE OF A DESIGNED ROCKER PROTEIN
Descriptor:designed rocker protein
Authors:Wang, T., Joh, N., Wu, Y., DeGrado, W.F., Hong, M.
Deposit date:2014-09-18
Release date:2014-12-24
Last modified:2015-01-14
Method:SOLUTION NMR
Cite:De novo design of a transmembrane Zn2+-transporting four-helix bundle.
Science, 346, 2014
3FP9
  • Download 3fp9
  • View 3fp9
Molmil generated image of 3fp9
CRYSTAL STRUCTURE OF INTERN DOMAIN OF PROTEASOME-ASSOCIATED ATPASE, MYCOBACTERIUM TUBERCULOSIS
Descriptor:Proteasome-associated ATPase
Authors:Li, H., Wang, T.
Deposit date:2009-01-04
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights on the Mycobacterium tuberculosis Proteasomal ATPase Mpa.
Structure, 17, 2009
3KCK
  • Download 3kck
  • View 3kck
Molmil generated image of 3kck
A NOVEL CHEMOTYPE OF KINASE INHIBITORS
Descriptor:Tyrosine-protein kinase JAK2, 3-chloro-4-(4H-3,4,7-triazadibenzo[cd,f]azulen-6-yl)phenol
Authors:Zuccola, H.J., Wang, T., Ledeboer, M.W.
Deposit date:2009-10-21
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3M9B
  • Download 3m9b
  • View 3m9b
Molmil generated image of 3m9b
CRYSTAL STRUCTURE OF THE AMINO TERMINAL COILED COIL DOMAIN AND THE INTER DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS PROTEASOMAL ATPASE MPA
Descriptor:Proteasome-associated ATPase
Authors:Li, H., Wang, T.
Deposit date:2010-03-21
Release date:2010-10-27
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.94 Å)
Cite:Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
3M9D
  • Download 3m9d
  • View 3m9d
Molmil generated image of 3m9d
CRYSTAL STRUCTURE OF THE PROKARYOTIC UBIQUINTIN-LIKE PROTEIN PUP COMPLEXED WITH THE HEXAMERIC PROTEASOMAL ATPASE MPA WHICH INCLUDES THE AMINO TERMINAL COILED COIL DOMAIN AND THE INTER DOMAIN
Descriptor:Proteasome-associated ATPase, Prokaryotic ubiquitin-like protein pup
Authors:Li, H., Wang, T.
Deposit date:2010-03-22
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
3M9H
  • Download 3m9h
  • View 3m9h
Molmil generated image of 3m9h
CRYSTAL STRUCTURE OF THE AMINO TERMINAL COILED COIL DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS PROTEASOMAL ATPASE MPA
Descriptor:Proteasome-associated ATPase
Authors:Li, H., Wang, T.
Deposit date:2010-03-22
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
3OHN
  • Download 3ohn
  • View 3ohn
Molmil generated image of 3ohn
CRYSTAL STRUCTURE OF THE FIMD TRANSLOCATION DOMAIN
Descriptor:Outer membrane usher protein FimD
Authors:Wang, T., Li, H.
Deposit date:2010-08-17
Release date:2011-06-01
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.011 Å)
Cite:Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
3ULI
  • Download 3uli
  • View 3uli
Molmil generated image of 3uli
HUMAN CYCLIN DEPENDENT KINASE 2 (CDK2) BOUND TO AZABENZIMIDAZOLE DERIVATIVE
Descriptor:Cyclin-dependent kinase 2, 1-(aminomethyl)-N-(3-{[6-bromo-2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-7-yl]amino}propyl)cyclopropanecarboxamide
Authors:Larsen, N.A., Tucker, J.A., Wang, T.
Deposit date:2011-11-10
Release date:2013-08-14
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKK epsilon kinases.
Bioorg.Med.Chem.Lett., 22, 2012
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan