Author results

1LZX
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RAT NEURONAL NOS HEME DOMAIN WITH NG-HYDROXY-L-ARGININE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1LZZ
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RAT NEURONAL NOS HEME DOMAIN WITH N-ISOPROPYL-N'-HYDROXYGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1M00
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RAT NEURONAL NOS HEME DOMAIN WITH N-BUTYL-N'-HYDROXYGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
3CIU
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SITE-SELECTIVE GLYCOSYLATION OF CYSTEINE-93 BETA ON THE SURFACE OF BOVINE HEMOGLOBIN AND ITS APPLICATION AS A NOVEL OXYGEN THERAPEUTIC
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bhatt, V.S., Zhang, Y., Sun, G., Wang, P.G., Palmer, A.F.
Deposit date:2008-03-11
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic
To be Published
3LU1
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CRYSTAL STRUCTURE ANALYSIS OF WBGU: A UDP-GALNAC 4-EPIMERASE
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, ...
Authors:Bhatt, V.S., Guo, C.Y., Zhao, G., Yi, W., Liu, Z.J., Wang, P.G.
Deposit date:2010-02-16
Release date:2010-07-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Altered architecture of substrate binding region defines the unique specificity of UDP-GalNAc 4-epimerases.
Protein Sci., 20, 2011
3PEL
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STRUCTURE OF GREYHOUND HEMOGLOBIN: ORIGIN OF HIGH OXYGEN AFFINITY
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bhatt, V.S., Zaldivar-Lopez, S., Harris, D.R., Couto, C.G., Wang, P.G., Palmer, A.F.
Deposit date:2010-10-26
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Greyhound hemoglobin: origin of high oxygen affinity.
Acta Crystallogr.,Sect.D, 67, 2011
3RU9
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SPECIFIC RECOGNITION OF N-ACETYLATED SUBSTRATES AND DOMAIN FLEXIBILITY IN WBGU: A UDP-GALNAC 4-EPIMERASE
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-04
Release date:2011-05-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Specific recognition of N-acetylated substrates and domain flexibility in WbgU: a UDP-GalNAc 4-epimerase
TO BE PUBLISHED
3RUA
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SPECIFIC RECOGNITION OF N-ACETYLATED SUBSTRATES AND DOMAIN FLEXIBILITY IN WBGU: A UDP-GALNAC 4-EPIMERASE
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UNKNOWN LIGAND, ...
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-04
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specific recognition of N-acetylated substrates and domain flexibility in WbgU: a UDP-GalNAc 4-epimerase
TO BE PUBLISHED
3RUC
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SPECIFIC RECOGNITION OF N-ACETYLATED SUBSTRATES AND DOMAIN FLEXIBILITY IN WBGU: A UDP-GALNAC 4-EPIMERASE
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, ...
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-04
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specific recognition of N-acetylated substrates and domain flexibility in WbgU: a UDP-GalNAc 4-epimerase
TO BE PUBLISHED
3RUD
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ALTERNATIVE ANALOGS AS VIABLE SUBSTRATES OF UDP-HEXOSE 4-EPIMERASES
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UNKNOWN LIGAND
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-05
Release date:2011-05-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Alternative analogs as viable substrates of UDP-hexose 4-epimerases
TO BE PUBLISHED
3RUE
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ALTERNATIVE ANALOGS AS VIABLE SUBSTRATES OF UDP-HEXOSE 4-EPIMERASES
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UNKNOWN LIGAND
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-05
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Alternative analogs as viable substrates of UDP-hexose 4-epimerases
TO BE PUBLISHED
3RUF
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ALTERNATIVE ANALOGS AS VIABLE SUBSTRATES OF UDP-HEXOSE 4-EPIMERASES
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE, ...
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-05
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative analogs as viable substrates of UDP-hexose 4-epimerases
TO BE PUBLISHED
3RUH
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ALTERNATIVE ANALOGS AS VIABLE SUBSTRATES OF UDP-HEXOSE 4-EPIMERASES
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4R,5R,6R)-6-(hydroxymethyl)-4,5-bis(oxidanyl)-3-(2-oxidanylidenepropyl)oxan-2-yl] hydrogen phosphate, ...
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-05
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Alternative analogs as viable substrates of UDP-hexose 4-epimerases
TO BE PUBLISHED
3RU7
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SPECIFIC RECOGNITION OF N-ACETYLATED SUBSTRATES AND DOMAIN FLEXIBILITY IN WBGU: A UDP-GALNAC 4-EPIMERASE
Descriptor:WbgU, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCINE, ...
Authors:Bhatt, V.S., Guan, W., Wang, P.G.
Deposit date:2011-05-04
Release date:2011-05-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specific recognition of N-acetylated substrates and domain flexibility in WbgU: a UDP-GalNAc 4-epimerase
TO BE PUBLISHED
3PI8
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SITE-SPECIFIC GLYCOSYLATION OF HEMOGLOBIN UTILIZING OXIME LIGATION CHEMISTRY AS A VIABLE ALTERNATIVE TO PEGYLATION
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bhatt, V.S., Styslinger, T.J., Zhang, N., Wang, P.G., Palmer, A.F.
Deposit date:2010-11-05
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:

3PI9
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SITE-SPECIFIC GLYCOSYLATION OF HEMOGLOBIN UTILIZING OXIME LIGATION CHEMISTRY AS A VIABLE ALTERNATIVE TO PEGYLATION
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bhatt, V.S., Styslinger, T.J., Zhang, N., Wang, P.G., Palmer, A.F.
Deposit date:2010-11-05
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:

3PIA
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SITE-SPECIFIC GLYCOSYLATION OF HEMOGLOBIN UTILIZING OXIME LIGATION CHEMISTRY AS A VIABLE ALTERNATIVE TO PEGYLATION
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bhatt, V.S., Styslinger, T.J., Zhang, N., Wang, P.G., Palmer, A.F.
Deposit date:2010-11-05
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:

1P6H
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RAT NEURONAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6I
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RAT NEURONAL NOS HEME DOMAIN WITH (4S)-N-(4-AMINO-5-[AMINOETHYL]AMINOPENTYL)-N'-NITROGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6J
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RAT NEURONAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6K
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RAT NEURONAL NOS D597N MUTANT HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, D-MANNITOL, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6L
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6M
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH (4S)-N-(4-AMINO-5-[AMINOETHYL]AMINOPENTYL)-N'-NITROGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6N
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1RS6
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RAT NEURONAL NOS HEME DOMAIN WITH D-LYSINE-D-NITROARGININE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, D-MANNITOL, ...
Authors:Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
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