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6JJP
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CRYSTAL STRUCTURE OF FAB OF A PD-1 MONOCLONAL ANTIBODY MW11-H317 IN COMPLEX WITH PD-1
分子名称:Heavy chain of MW11-h317, light chain of MW11-h317, Programmed cell death protein 1, ...
著者Wang, M., Wang, J., Wang, R., Jiao, S., Wang, S., Zhang, J., Zhang, M.
登録日2019-02-26
公開日2019-10-30
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation.
Commun Biol, 2, 2019
2FXY
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SOLUTION STRUCTURE OF 55-72 SEGMENT OF STAPHYLOCOCCAL NUCLEASE
分子名称:18-mer peptide from Thermonuclease
著者Wang, M., Shan, L., Wang, J.F.
登録日2006-02-07
公開日2006-12-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Two peptide fragments G55-I72 and K97-A109 from staphylococcal nuclease exhibit different behaviors in conformational preferences for helix formation
Biopolymers, 83, 2006
2FXZ
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SOLUTION STRUCTURE OF 97-109 SEGMENT OF STAPHYLOCOCCAL NUCLEASE
分子名称:13-mer peptide from Thermonuclease
著者Wang, M., Shan, L., Wang, J.F.
登録日2006-02-07
公開日2006-12-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Two peptide fragments G55-I72 and K97-A109 from staphylococcal nuclease exhibit different behaviors in conformational preferences for helix formation
Biopolymers, 83, 2006
2KQ3
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SOLUTION STRUCTURE OF SNASE140
分子名称:Thermonuclease
著者Wang, M., Feng, Y., Yao, H., Wang, J.
登録日2009-10-26
公開日2010-05-26
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Importance of the C-Terminal Loop L137-S141 for the Folding and Folding Stability of Staphylococcal Nuclease
Biochemistry, 49, 2010
3NCI
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RB69 DNA POLYMERASE TERNARY COMPLEX WITH DCTP OPPOSITE DG AT 1.8 ANGSTROM RESOLUTION
分子名称:DNA polymerase, DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Blaha, G., Steitz, T.A., Konigsberg, W.H., Wang, J.
登録日2010-06-04
公開日2011-02-02
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex.
Biochemistry, 50, 2011
4QY0
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8
分子名称:hemagglutinin, N-ACETYL-D-GLUCOSAMINE
著者Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
登録日2014-07-23
公開日2015-01-28
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8 IN COMPLEX WITH AVIAN RECEPTOR
分子名称:hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
著者Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
登録日2014-07-23
公開日2015-01-28
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOG
分子名称:hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID
著者Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
登録日2014-07-23
公開日2015-01-28
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4X1B
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HUMAN SERUM TRANSFERRIN WITH FERRIC ION BOUND AT THE C-LOBE ONLY
分子名称:Serotransferrin, FE (III) ION, MALONATE ION, ...
著者Wang, M., Zhang, H., Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
4X1D
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YTTERBIUM-BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, YTTERBIUM (III) ION, MALONATE ION, ...
著者Wang, M., Zhang, H., Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
5ZQY
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CRYSTAL STRUCTURE OF A POLY(ADP-RIBOSE) GLYCOHYDROLASE
分子名称:Poly(ADP-ribose) glycohydrolase ARH3, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
著者Wang, M., Yuan, Z., Ma, Y., Wang, J., Liu, X.
登録日2018-04-20
公開日2018-08-15
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (1.577 Å)
主引用文献Structure-function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation.
J. Biol. Chem., 293, 2018
2KJ4
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SOLUTION STRUCTURE OF THE COMPLEX OF VEK-30 AND PLASMINOGEN KRINGLE 2
分子名称:plasminogen, VEK-30
著者Wang, M., Zajicek, J., Prorok, M., Castellin, F.J.
登録日2009-05-21
公開日2009-10-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the complex of VEK-30 and plasminogen kringle 2.
J.Struct.Biol., 169, 2010
1AMO
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THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES
分子名称:NADPH-CYTOCHROME P450 REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ...
著者Wang, M., Roberts, D.L., Paschke, R., Shea, T.M., Masters, B.S.S., Kim, J.J.P.
登録日1997-06-17
公開日1998-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes.
Proc.Natl.Acad.Sci.USA, 94, 1997
1NHU
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HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR
分子名称:HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE, (2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-BENZYL)-AMINO]-3-PHENYL-PROPIONIC ACID
著者Wang, M., Ng, K.K.S., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bedard, J., Morin, N., Nguyen-Ba, N., Alaoui-Ismaili, M.H., Bethell, R.C., James, M.N.G.
登録日2002-12-19
公開日2003-03-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition
J.Biol.Chem., 278, 2003
1NHV
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HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR
分子名称:HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE, (2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID
著者Wang, M., Ng, K.K.S., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bedard, J., Morin, N., Nguyen-Ba, N., Alaoui-Ismaili, M.H., Bethell, R.C., James, M.N.G.
登録日2002-12-19
公開日2003-03-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition
J.Biol.Chem., 278, 2003
2F48
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CRYSTAL STRUCTURE OF A NOVEL FRUCTOSE 1,6-BISPHOSPHATE AND ALF3 CONTAINING PYROPHOSPHATE-DEPENDENT PHOSPHOFRUCTO-1-KINASE COMPLEX FROM BORRELIA BURGDORFERI
分子名称:diphosphate--fructose-6-phosphate 1-phosphotransferase, BETA-FRUCTOSE-1,6-DIPHOSPHATE, ALUMINUM FLUORIDE
著者Wang, M.
登録日2005-11-22
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal Structure of A Novel Fructose 1,6-Bisphosphate and AlF3 containing Pyrophosphate-dependent Phosphofructo-1-kinase Complex from Borrelia burgdorferi
TO BE PUBLISHED
5EQJ
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CRYSTAL STRUCTURE OF THE TWO-SUBUNIT TRNA M1A58 METHYLTRANSFERASE FROM SACCHAROMYCES CEREVISIAE
分子名称:tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61
著者Zhu, Y., Wang, M., Wang, C., Fan, X., Jiang, X., Teng, M., Li, X.
登録日2015-11-13
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
5ERG
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CRYSTAL STRUCTURE OF THE TWO-SUBUNIT TRNA M1A58 METHYLTRANSFERASE TRM6-TRM61 IN COMPLEX WITH SAM
分子名称:tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, S-ADENOSYLMETHIONINE
著者Zhu, Y., Wang, M., Wang, C., Fan, X., Jiang, X., Teng, M., Li, X.
登録日2015-11-14
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
2PL5
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CRYSTAL STRUCTURE OF HOMOSERINE O-ACETYLTRANSFERASE FROM LEPTOSPIRA INTERROGANS
分子名称:Homoserine O-acetyltransferase, GLYCEROL
著者Liu, L., Wang, M., Wang, Y., Wei, Z., Xu, H., Gong, W.
登録日2007-04-19
公開日2007-11-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans
Biochem.Biophys.Res.Commun., 363, 2007
3LZI
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RB69 DNA POLYMERASE (Y567A) TERNARY COMPLEX WITH DATP OPPOSITE 7,8-DIHYDRO-8-OXOGUANINE
分子名称:DNA polymerase, DNA (5'-D(P*TP*CP*AP*(8OG)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Beckman, J., Blaha, G., Wang, J., Konigsberg, W.H.
登録日2010-03-01
公開日2010-05-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3LZJ
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RB69 DNA POLYMERASE (Y567A) TERNARY COMPLEX WITH DCTP OPPOSITE 7,8-DIHYDRO-8-OXOGUANINE
分子名称:DNA polymerase, DNA (5'-D(P*TP*CP*AP*(8OG)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Beckman, J., Blaha, G., Wang, J., Konigsberg, W.H.
登録日2010-03-01
公開日2010-05-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3NAE
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RB69 DNA POLYMERASE (Y567A) TERNARY COMPLEX WITH DATP OPPOSITE GUANIDINOHYDANTOIN
分子名称:DNA polymerase, DNA (5'-D(*TP*CP*AP*(G35)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Beckman, J., Blaha, G., Wang, J., Konigsberg, W.H.
登録日2010-06-01
公開日2010-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Biochemistry, 49, 2010
3NDK
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RB69 DNA POLYMERASE (Y567A) TERNARY COMPLEX WITH DCTP OPPOSITE DG
分子名称:DNA polymerase, DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Wang, J., Konigsberg, W.H.
登録日2010-06-07
公開日2011-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NE6
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RB69 DNA POLYMERASE (S565G/Y567A) TERNARY COMPLEX WITH DCTP OPPOSITE DG
分子名称:DNA polymerase, DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Wang, J., Konigsberg, W.H.
登録日2010-06-08
公開日2011-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NGI
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RB69 DNA POLYMERASE (Y567A) TERNARY COMPLEX WITH DTTP OPPOSITE DG
分子名称:DNA polymerase, DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M., Wang, J., Konigsberg, W.H.
登録日2010-06-11
公開日2011-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.886 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011