Author results

6JEP
  • Download 6jep
  • View 6jep
Molmil generated image of 6jep
STRUCTURE OF A NEUTRALIZING ANTIBODY BOUND TO THE ZIKA ENVELOPE PROTEIN DOMAIN III
Descriptor:heavy chain of Fab ZK2B10, light chain of Fab ZK2B10, Genome polyprotein
Authors:Wang, L., Wang, R.K., Wang, L., Ben, H.J., Yu, L., Gao, F., Shi, X.L., Yin, C.B., Zhang, F.C., Xiang, Y., Zhang, L.Q.
Deposit date:2019-02-07
Release date:2019-05-15
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.316 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
6JFH
  • Download 6jfh
  • View 6jfh
Molmil generated image of 6jfh
THE ASYMMETRIC-RECONSTRUCTED CRYO-EM STRUCTURE OF ZIKA VIRUS-FABZK2B10 COMPLEX
Descriptor:ZIKV structural E protein, strutural protein M, FabZK2B10 heavy chain, ...
Authors:Wang, L., Wang, R.K., Wang, L., Ben, H.J., Yu, L., Gao, F., Shi, X.L., Yin, C.B., Zhang, F.C., Xiang, Y., Zhang, L.Q.
Deposit date:2019-02-08
Release date:2019-04-10
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
6JFI
  • Download 6jfi
  • View 6jfi
Molmil generated image of 6jfi
THE SYMMETRIC-RECONSTRUCTED CRYO-EM STRUCTURE OF ZIKA VIRUS-FABZK2B10 COMPLEX
Descriptor:ZIKV structural protein E, strutural protein M, FabZK2B10 heavy chain, ...
Authors:Wang, L., Wang, R.K., Wang, L., Ben, H.J., Yu, L., Gao, F., Shi, X.L., Yin, C.B., Zhang, F.C., Xiang, Y., Zhang, L.Q.
Deposit date:2019-02-08
Release date:2019-04-10
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
3Q47
  • Download 3q47
  • View 3q47
Molmil generated image of 3q47
CRYSTAL STRUCTURE OF TPR DOMAIN OF CHIP COMPLEXED WITH PSEUDOPHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
  • Download 3q49
  • View 3q49
Molmil generated image of 3q49
CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH HSP70-C PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Hsp70-C peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.543 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q4A
  • Download 3q4a
  • View 3q4a
Molmil generated image of 3q4a
CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH PHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.542 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
4Y52
  • Download 4y52
  • View 4y52
Molmil generated image of 4y52
CRYSTAL STRUCTURE OF 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION.
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, L., Chong, J., Wang, D.
Deposit date:2015-02-11
Release date:2015-07-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
4Y7N
  • Download 4y7n
  • View 4y7n
Molmil generated image of 4y7n
THE STRUCTURE INSIGHT INTO 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION.
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2,DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, L., Chong, J., Wang, D.
Deposit date:2015-02-15
Release date:2015-07-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
3TJU
  • Download 3tju
  • View 3tju
Molmil generated image of 3tju
CRYSTAL STRUCTURE OF HUMAN GRANZYME H WITH AN INHIBITOR
Descriptor:Granzyme H, Ac-PTSY-CMK inhibitor, SULFATE ION
Authors:Wang, L., Zhang, K., Wu, L., Tong, L., Sun, F., Fan, Z.
Deposit date:2011-08-25
Release date:2011-12-28
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
3TJV
  • Download 3tjv
  • View 3tjv
Molmil generated image of 3tjv
CRYSTAL STRUCTURE OF HUMAN GRANZYME H WITH A PEPTIDYL SUBSTRATE
Descriptor:Granzyme H, PTSYAGDDSG, SULFATE ION
Authors:Wang, L., Zhang, K., Wu, L., Tong, L., Sun, F., Fan, Z.
Deposit date:2011-08-25
Release date:2011-12-28
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
3TK9
  • Download 3tk9
  • View 3tk9
Molmil generated image of 3tk9
CRYSTAL STRUCTURE OF HUMAN GRANZYME H
Descriptor:Granzyme H, SULFATE ION
Authors:Wang, L., Zhang, K., Wu, L., Tong, L., Sun, F., Fan, Z.
Deposit date:2011-08-25
Release date:2011-12-28
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
4GA7
  • Download 4ga7
  • View 4ga7
Molmil generated image of 4ga7
CRYSTAL STRUCTURE OF HUMAN SERPINB1 MUTANT
Descriptor:Leukocyte elastase inhibitor
Authors:Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
4GAW
  • Download 4gaw
  • View 4gaw
Molmil generated image of 4gaw
CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME H
Descriptor:Granzyme H, SULFATE ION, CHLORIDE ION
Authors:Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
2JRT
  • Download 2jrt
  • View 2jrt
Molmil generated image of 2jrt
NMR SOLUTION STRUCTURE OF THE PROTEIN CODED BY GENE RHOS4_12090 OF RHODOBACTER SPHAEROIDES. NORTHEAST STRUCTURAL GENOMICS TARGET RHR5
Descriptor:Uncharacterized protein
Authors:Wang, L., Chen, C., Nwosu, C., Cunningham, K., Owens, L., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-28
Release date:2007-08-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides.
To be Published
4JR4
  • Download 4jr4
  • View 4jr4
Molmil generated image of 4jr4
CRYSTAL STRUCTURE OF MTB DSBA (OXIDIZED)
Descriptor:Possible conserved membrane or secreted protein, SULFATE ION
Authors:Wang, L.
Deposit date:2013-03-21
Release date:2013-07-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structure analysis of the extracellular domain reveals disulfide bond forming-protein properties of Mycobacterium tuberculosis Rv2969c.
Protein Cell, 4, 2013
4JR6
  • Download 4jr6
  • View 4jr6
Molmil generated image of 4jr6
CRYSTAL STRUCTURE OF DSBA FROM MYCOBACTERIUM TUBERCULOSIS (REDUCED)
Descriptor:Possible conserved membrane or secreted protein, SULFATE ION
Authors:Wang, L.
Deposit date:2013-03-21
Release date:2013-07-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Structure analysis of the extracellular domain reveals disulfide bond forming-protein properties of Mycobacterium tuberculosis Rv2969c.
Protein Cell, 4, 2013
4NSC
  • Download 4nsc
  • View 4nsc
Molmil generated image of 4nsc
CRYSTAL STRUCTURE OF CBARA1 IN THE APO-FORM
Descriptor:Calcium uptake protein 1, mitochondrial
Authors:Wang, L., Yang, X., Li, S., Shen, Y.
Deposit date:2013-11-28
Release date:2014-02-26
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.
Embo J., 33, 2014
4NSD
  • Download 4nsd
  • View 4nsd
Molmil generated image of 4nsd
CRYSTAL STRUCTURE OF CBARA1 IN THE CA2+ BINDING FORM
Descriptor:Calcium uptake protein 1, mitochondrial, CALCIUM ION, ...
Authors:Wang, L., Yang, X., Li, S., Shen, Y.
Deposit date:2013-11-28
Release date:2014-02-26
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.
Embo J., 33, 2014
5YR2
  • Download 5yr2
  • View 5yr2
Molmil generated image of 5yr2
STRUCTURE OF CPGFP66BPA
Descriptor:Green fluorescent protein
Authors:Wang, L., Kang, F., Wang, J.
Deposit date:2017-11-08
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structure of cpGFP66BPA
To Be Published
6LR0
  • Download 6lr0
  • View 6lr0
Molmil generated image of 6lr0
STRUCTURE OF HUMAN BILE SALT EXPORTER ABCB11
Descriptor:Bile salt export pump
Authors:Wang, L., Hou, W.T., Chen, L., Jiang, Y.L., Xu, D., Sun, L.F., Zhou, C.Z., Chen, Y.
Deposit date:2020-01-15
Release date:2020-04-15
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of human bile salts exporter ABCB11.
Cell Res., 30, 2020
6VP0
  • Download 6vp0
  • View 6vp0
Molmil generated image of 6vp0
HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 1 IN COMPLEX WITH OLEOYL-COA
Descriptor:Diacylglycerol O-acyltransferase 1, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Wang, L., Qian, H., Han, Y., Nian, Y., Ren, Z., Zhang, H., Hu, L., Prasad, B.V.V., Yan, N., Zhou, M.
Deposit date:2020-02-01
Release date:2020-05-13
Last modified:2020-06-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and mechanism of human diacylglycerol O-acyltransferase 1.
Nature, 581, 2020
1BLR
  • Download 1blr
  • View 1blr
Molmil generated image of 1blr
NMR SOLUTION STRUCTURE OF HUMAN CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II, 22 STRUCTURES
Descriptor:CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II
Authors:Wang, L., Li, Y., Abilddard, F., Yan, H., Markely, J.
Deposit date:1998-07-20
Release date:1999-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Biochemistry, 37, 1998
1MLW
  • Download 1mlw
  • View 1mlw
Molmil generated image of 1mlw
CRYSTAL STRUCTURE OF HUMAN TRYPTOPHAN HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN COFACTOR AND FE(III)
Descriptor:Tryptophan 5-monooxygenase, FE (III) ION, 7,8-DIHYDROBIOPTERIN
Authors:Wang, L., Erlandsen, H., Haavik, J., Knappskog, P.M., Stevens, R.C.
Deposit date:2002-08-31
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin
Biochemistry, 41, 2002
1Y2M
  • Download 1y2m
  • View 1y2m
Molmil generated image of 1y2m
CRYSTAL STRUCTURE OF PHENYLALANINE AMMONIA-LYASE FROM YEAST RHODODPORIDIUM TORULOIDES
Descriptor:Phenylalanine ammonia-lyase
Authors:Wang, L., Gamez, A., Sarkissian, C.N., Straub, M., Patch, M.G., Han, G.W., Scriver, C.R., Stevens, R.C.
Deposit date:2004-11-22
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria.
Mol.Genet.Metab., 86, 2005
1ZOK
  • Download 1zok
  • View 1zok
Molmil generated image of 1zok
PDZ1 DOMAIN OF SYNAPSE ASSOCIATED PROTEIN 97
Descriptor:Presynaptic protein SAP97
Authors:Wang, L., Piserchio, A., Mierke, D.F.
Deposit date:2005-05-13
Release date:2005-06-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors.
J.Biol.Chem., 280, 2005
168889
PDB entries from 2020-09-16