Author results

6IO4
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-29
公開日2019-07-03
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IO6
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A AT NON-CATALYTIC SITE
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-29
公開日2019-07-03
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IOJ
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GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A (APO-FORM)
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-30
公開日2019-07-03
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
5Z3W
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MALATE DEHYDROGENASE BINDS SILVER AT C113
分子名称:Malate dehydrogenase, SILVER ION
著者Wang, H., Wang, M., Sun, H.
登録日2018-01-09
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of silver-bound malate dehydrogenase
To Be Published
5ZM8
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CRYSTAL STRUCTURE OF ORP2-ORD IN COMPLEX WITH PI(4,5)P2
分子名称:Oxysterol-binding protein-related protein 2, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate
著者Wang, H., Dong, J.Q., Wang, J., Wu, J.W.
登録日2018-04-01
公開日2019-01-02
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).
Mol. Cell, 73, 2019
1WWI
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CRYSTAL STRUCTURE OF TTK003001566 FROM THERMUS THERMOPHILUS HB8
分子名称:hypothetical protein TTHA1479
著者Wang, H., Murayama, K., Terada, T., Chen, L., Liu, Z.J., Wang, B.C., Shirouzu, M., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-01-05
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of ttk003001566 from Thermus Thermophilus HB8
TO BE PUBLISHED
2CSL
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CRYSTAL STRUCTURE OF TTHA0137 FROM THERMUS THERMOPHILUS HB8
分子名称:protein translation initiation inhibitor
著者Wang, H., Murayama, K., Terada, T., Chen, L., Jin, Z., Chrzas, J., Liu, Z.J., Wang, B.C., Shirouzu, M., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-22
公開日2005-11-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of TTHA0137 from Thermus Thermophilus HB8
To be Published
2DY1
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CRYSTAL STRUCTURE OF EF-G-2 FROM THERMUS THERMOPHILUS
分子名称:Elongation factor G, MAGNESIUM ION, GUANOSINE-5'-TRIPHOSPHATE
著者Wang, H., Takemoto, C., Murayama, K., Terada, T., Chen, L., Liu, Z.J., Wang, B.C., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-04
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of EF-G-2 from Thermus thermophilus
To be Published
2NZ0
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CRYSTAL STRUCTURE OF POTASSIUM CHANNEL KV4.3 IN COMPLEX WITH ITS REGULATORY SUBUNIT KCHIP1 (CASP TARGET)
分子名称:Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, CALCIUM ION, ...
著者Wang, H., Yan, Y., Shen, Y., Chen, L., Wang, K.
登録日2006-11-22
公開日2006-12-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for modulation of Kv4 K(+) channels by auxiliary KChIP subunits.
Nat.Neurosci., 10, 2007
3NGN
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CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAIN IN COMPLEX WITH AMP
分子名称:CCR4-NOT transcription complex subunit 6-like, ADENOSINE MONOPHOSPHATE
著者Wang, H., Morita, M., Yang, W., Bartlam, M., Yamamoto, T., Rao, Z.
登録日2010-06-12
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGO
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CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAIN IN COMPLEX WITH POLY(A) DNA
分子名称:CCR4-NOT transcription complex subunit 6-like, 5'-D(*AP*AP*AP*A)-3', MAGNESIUM ION
著者Wang, H., Morita, M., Yang, W., Bartlam, M., Yamamoto, T., Rao, Z.
登録日2010-06-12
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGQ
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CRYSTAL STRUCTURE OF THE HUMAN CNOT6L NUCLEASE DOMAIN
分子名称:CCR4-NOT transcription complex subunit 6-like, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, MAGNESIUM ION
著者Wang, H., Morita, M., Yang, W., Bartlam, M., Yamamoto, T., Rao, Z.
登録日2010-06-13
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
4RGW
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CRYSTAL STRUCTURE OF A TAF1-TAF7 COMPLEX IN HUMAN TRANSCRIPTION FACTOR IID
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7, GLYCEROL
著者Wang, H., Curran, E.C., Hinds, T.R., Wang, E.H., Zheng, N.
登録日2014-09-30
公開日2014-12-03
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell Res., 24, 2014
5C3I
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CRYSTAL STRUCTURE OF THE QUATERNARY COMPLEX OF HISTONE H3-H4 HETERODIMER WITH CHAPERONE ASF1 AND THE REPLICATIVE HELICASE SUBUNIT MCM2
分子名称:Histone chaperone ASF1A, Histone H3.1, Histone H4, ...
著者Wang, H., Wang, M., Yang, N., Xu, R.M.
登録日2015-06-17
公開日2015-07-29
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Protein Cell, 6, 2015
1ZKL
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MULTIPLE DETERMINANTS FOR INHIBITOR SELECTIVITY OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASES
分子名称:High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, ZINC ION, MAGNESIUM ION, ...
著者Wang, H., Liu, Y., Chen, Y., Robinson, H., Ke, H.
登録日2005-05-03
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7
J.Biol.Chem., 280, 2005
2H40
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF UNLIGANDED PDE5
分子名称:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION
著者Wang, H., Liu, Y., Huai, Q., Cai, J., Zoraghi, R., Francis, S.H., Corbin, J.D., Robinson, H., Xin, Z., Lin, G., Ke, H.
登録日2006-05-23
公開日2006-06-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
2PW3
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STRUCTURE OF THE PDE4D-CAMP COMPLEX
分子名称:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
著者Wang, H., Robinson, H., Ke, H.
登録日2007-05-10
公開日2007-10-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10.
J.Mol.Biol., 371, 2007
3ECM
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CRYSTAL STRUCTURE OF THE UNLIGANDED PDE8A CATALYTIC DOMAIN
分子名称:High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, ZINC ION, MAGNESIUM ION
著者Wang, H., Yan, Z., Yang, S., Cai, J., Robinson, H., Ke, H.
登録日2008-09-01
公開日2008-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity
Biochemistry, 47, 2008
3ECN
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CRYSTAL STRUCTURE OF PDE8A CATALYTIC DOMAIN IN COMPLEX WITH IBMX
分子名称:High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, 3-ISOBUTYL-1-METHYLXANTHINE, ZINC ION, ...
著者Wang, H., Yan, Z., Yang, S., Cai, J., Robinson, H., Ke, H.
登録日2008-09-01
公開日2008-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity
Biochemistry, 47, 2008
3K3E
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CRYSTAL STRUCTURE OF THE PDE9A CATALYTIC DOMAIN IN COMPLEX WITH (R)-BAY73-6691
分子名称:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ZINC ION, MAGNESIUM ION, ...
著者Wang, H., Luo, X., Ye, M., Hou, J., Robinson, H., Ke, H.
登録日2009-10-02
公開日2010-02-16
最終更新日2013-11-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis
J.Med.Chem., 53, 2010
3K3H
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CRYSTAL STRUCTURE OF THE PDE9A CATALYTIC DOMAIN IN COMPLEX WITH (S)-BAY73-6691
分子名称:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ZINC ION, MAGNESIUM ION, ...
著者Wang, H., Luo, X., Ye, M., Hou, J., Robinson, H., Ke, H.
登録日2009-10-02
公開日2010-02-16
最終更新日2013-11-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis
J.Med.Chem., 53, 2010
3LFV
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CRYSTAL STRUCTURE OF UNLIGANDED PDE5A GAF DOMAIN
分子名称:cGMP-specific 3',5'-cyclic phosphodiesterase
著者Wang, H., Robinson, H., Ke, H.
登録日2010-01-18
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
J.Biol.Chem., 285, 2010
3MF0
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CRYSTAL STRUCTURE OF PDE5A GAF DOMAIN (89-518)
分子名称:cGMP-specific 3',5'-cyclic phosphodiesterase
著者Wang, H., Robinson, H., Ke, H.
登録日2010-04-01
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
J.Biol.Chem., 285, 2010
3V93
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UNLIGANDED STRUCTURE OF TCRPDEC1 CATALYTIC DOMAIN
分子名称:Cyclic nucleotide specific phosphodiesterase, ZINC ION, MAGNESIUM ION
著者Wang, H., Kunz, S., Chen, G., Seebeck, T., Wan, Y., Robinson, H., Martinelli, S., Ke, H.
登録日2011-12-23
公開日2012-02-22
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors.
J.Biol.Chem., 287, 2012
3V94
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TCRPDEC1 CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR WYQ16
分子名称:Cyclic nucleotide specific phosphodiesterase, propan-2-yl {[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]sulfonyl}carbamate, ZINC ION, ...
著者Wang, H., Kunz, S., Chen, G., Seebeck, T., Wan, Y., Robinson, H., Martinelli, S., Ke, H.
登録日2011-12-23
公開日2012-02-22
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献TcrPDEC1 catalytic domain in complex with inhibitor wyq16
To be Published