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1YM0
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CRYSTAL STRUCTURE OF EARTHWORM FIBRINOLYTIC ENZYME COMPONENT B: A NOVEL, GLYCOSYLATED TWO-CHAINED TRYPSIN
Descriptor:fibrinotic enzyme component B, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Wang, F., Wang, C., Li, M., Zhang, J.P., Gui, L.L., An, X.M., Chang, W.R.
Deposit date:2005-01-20
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of earthworm fibrinolytic enzyme component B: a novel, glycosylated two-chained trypsin.
J.Mol.Biol., 348, 2005
4YY0
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THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/CHICKEN/TAIWAN/A2837/2013)
Descriptor:HA1, HA2, N-ACETYL-D-GLUCOSAMINE
Authors:Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.
Deposit date:2015-03-23
Release date:2016-03-23
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)
To Be Published
4YY1
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THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/CHICKEN/TAIWAN/A2837/2013) IN COMPLEX WITH HUMAN RECEPTOR ANALOG 6'SLNLN
Descriptor:HA1, HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.
Deposit date:2015-03-23
Release date:2016-03-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)
To Be Published
4YY7
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THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/CHICKEN/TAIWAN/A2837/2013) IN COMPLEX WITH AVIAN RECEPTOR ANALOG 3'SLNLN
Descriptor:HA1, HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.
Deposit date:2015-03-23
Release date:2016-03-23
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)
To Be Published
4YY9
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THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/TAIWAN/2/2013)
Descriptor:HA1, HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.
Deposit date:2015-03-23
Release date:2016-04-13
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structure of hemagglutinin from a H6N1 influenza virus (A/Taiwan/2/2013) at 2.6 Angstroms resolution
To Be Published
4YYA
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THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/TAIWAN/2/2013) IN COMPLEX WITH AVIAN RECEPTOR ANALOG 3'SLNLN
Descriptor:HA1, HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.
Deposit date:2015-03-23
Release date:2016-04-13
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:Structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)
To Be Published
4YYB
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THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/TAIWAN/2/2013) IN COMPLEX WITH HUMAN RECEPTOR ANALOG 6'SLNLN
Descriptor:HA1, HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.
Deposit date:2015-03-23
Release date:2016-04-13
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:Structure of hemagglutinin from a H6N1 influenza virus (A/Taiwan/2/2013) at 2.6 Angstroms resolution
To Be Published
2Y1Q
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CRYSTAL STRUCTURE OF CLPC N-TERMINAL DOMAIN
Descriptor:NEGATIVE REGULATOR OF GENETIC COMPETENCE CLPC/MECB, SULFATE ION
Authors:Wang, F., Mei, Z.Q., Wang, J.W., Shi, Y.G.
Deposit date:2010-12-10
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and Mechanism of the Hexameric Meca-Clpc Molecular Machine.
Nature, 471, 2011
2Y1R
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STRUCTURE OF MECA121 & CLPC N-DOMAIN COMPLEX
Descriptor:NEGATIVE REGULATOR OF GENETIC COMPETENCE CLPC/MECB, ADAPTER PROTEIN MECA 1, S,R MESO-TARTARIC ACID
Authors:Wang, F., Mei, Z.Q., Wang, J.W., Shi, Y.G.
Deposit date:2010-12-10
Release date:2011-03-16
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:Structure and Mechanism of the Hexameric Meca-Clpc Molecular Machine.
Nature, 471, 2011
3JTN
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF YPBH
Descriptor:Adapter protein mecA 2, IODIDE ION
Authors:Wang, F., Mei, Z., Qi, Y., Yan, C., Wang, J., Shi, Y.
Deposit date:2009-09-14
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of the MecA degradation tag
To be Published
3JTO
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF YPBH
Descriptor:Adapter protein mecA 2
Authors:Wang, F., Mei, Z., Qi, Y., Yan, C., Wang, J., Shi, Y.
Deposit date:2009-09-14
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the MecA Degradation Tag
To be Published
3JTP
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF MECA
Descriptor:Adapter protein mecA 1, IODIDE ION
Authors:Wang, F., Mei, Z., Qi, Y., Yan, C., Wang, J., Shi, Y.
Deposit date:2009-09-14
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:crystal structure of the MecA degradation tag
To be Published
3NBH
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CRYSTAL STRUCTURE OF HUMAN RMI1C-RMI2 COMPLEX
Descriptor:RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2
Authors:Wang, F., Yang, Y., Singh, T.R., Busygina, V., Guo, R., Wan, K., Wang, W., Sung, P., Meetei, A.R., Lei, M.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
3NBI
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CRYSTAL STRUCTURE OF HUMAN RMI1 N-TERMINUS
Descriptor:RecQ-mediated genome instability protein 1
Authors:Wang, F., Yang, Y., Singh, T.R., Busygina, V., Guo, R., Wan, K., Wang, W., Sung, P., Meetei, A.R., Lei, M.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
3PXG
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STRUCTURE OF MECA121 AND CLPC1-485 COMPLEX
Descriptor:Adapter protein mecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Wang, F., Mei, Z.Q., Wang, J.W., Shi, Y.G.
Deposit date:2010-12-09
Release date:2011-03-16
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (3.654 Å)
Cite:Structure and mechanism of the hexameric MecA-ClpC molecular machine.
Nature, 471, 2011
3PXI
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STRUCTURE OF MECA108:CLPC
Descriptor:Adapter protein mecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Wang, F., Mei, Z.Q., Wang, J.W., Shi, Y.G.
Deposit date:2010-12-09
Release date:2011-03-16
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (6.926 Å)
Cite:Structure and mechanism of the hexameric MecA-ClpC molecular machine.
Nature, 471, 2011
4RL1
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STRUCTURAL AND FUNCTIONAL ANALYSIS OF A LOADING ACYLTRANSFERASE FROM THE AVERMECTIN MODULAR POLYKETIDE SYNTHASE
Descriptor:Type I polyketide synthase AVES 1
Authors:Wang, F., Wang, Y., Zheng, J.
Deposit date:2014-10-15
Release date:2015-01-28
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase.
Acs Chem.Biol., 10, 2015
2QEF
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X-RAY STRUCTURE OF 7-DEAZA-DG AND Z3DU MODIFIED DUPLEX CGCGAATXCZCG
Descriptor:DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*(ZDU)P*DCP*(7GU)P*DCP*DG)-3')
Authors:Wang, F., Li, F., Ganguly, M., Marky, L.A., Gold, B., Egli, M., Stone, M.P.
Deposit date:2007-06-25
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.
Biochemistry, 47, 2008
2QEG
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B-DNA WITH 7-DEAZA-DG MODIFICATION
Descriptor:DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*(7GU)P*DCP*DG)-3')
Authors:Wang, F., Li, F., Ganguly, M., Marky, L.A., Gold, B., Egli, M., Stone, M.P.
Deposit date:2007-06-25
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.
Biochemistry, 47, 2008
2PFC
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STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS RV0098
Descriptor:Hypothetical protein Rv0098/MT0107, PALMITIC ACID
Authors:Wang, F., Sacchettini, J.C.
Deposit date:2007-04-04
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence.
Chem.Biol., 14, 2007
5EJL
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MRKH, A NOVEL C-DI-GMP DEPENDENCE TRANSCRIPTION REGULATORY FACTOR.
Descriptor:Klebsiella pneumoniae genome assembly NOVST, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), SULFATE ION, ...
Authors:Wang, F., Zhu, D., Gu, L.
Deposit date:2015-11-02
Release date:2016-10-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The PilZ domain of MrkH represents a novel DNA binding motif
Protein Cell, 7, 2016
5GWZ
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THE STRUCTURE OF PORCINE EPIDEMIC DIARRHEA VIRUS MAIN PROTEASE IN COMPLEX WITH AN INHIBITOR
Descriptor:PEDV main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Wang, F., Chen, C., Yang, K., Liu, X., Liu, H., Xu, Y., Chen, X., Liu, X., Cai, Y., Yang, H.
Deposit date:2016-09-14
Release date:2017-03-29
Last modified:2017-04-26
Method:X-RAY DIFFRACTION (2.444 Å)
Cite:Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus
J. Med. Chem., 60, 2017
6NAV
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CRYO-EM RECONSTRUCTION OF SULFOLOBUS ISLANDICUS LAL14/1 PILUS
Descriptor:M9UD72
Authors:Wang, F., Cvirkaite-Krupovic, V., Prangishvili, D., Krupovic, M., Egelman, E.H.
Deposit date:2018-12-06
Release date:2019-05-08
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:An extensively glycosylated archaeal pilus survives extreme conditions.
Nat Microbiol, 4, 2019
2GDN
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CRYSTAL STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS BETA-LACTAMASE
Descriptor:Beta-lactamase
Authors:Wang, F., Cassidy, C., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-03-16
Release date:2006-04-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal Structure and Activity Studies of the Mycobacterium tuberculosis {beta}-Lactamase Reveal Its Critical Role in Resistance to {beta}-Lactam Antibiotics.
Antimicrob.Agents Chemother., 50, 2006
2H9I
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MYCOBACTERIUM TUBERCULOSIS INHA BOUND WITH ETH-NAD ADDUCT
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
Authors:Wang, F., Sacchettini, J.C.
Deposit date:2006-06-09
Release date:2007-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of thioamide drug action against tuberculosis and leprosy.
J.Exp.Med., 204, 2007