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4HLU
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BU of 4hlu by Molmil
Structure of the EcfA-A' heterodimer bound to ADP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA, ...
Authors:Wang, D.N, Karpowich, N.K.
Deposit date:2012-10-17
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7003 Å)
Cite:Assembly and mechanism of a group II ECF transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
7LO7
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BU of 7lo7 by Molmil
NorA in complex with Fab25
Descriptor: Fab25 Heavy Chain, Fab25 Light Chain, Quinolone resistance protein NorA
Authors:Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N.
Deposit date:2021-02-09
Release date:2022-04-20
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
7LO8
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BU of 7lo8 by Molmil
NorA in complex with Fab36
Descriptor: Fab36 Heavy Chain, Fab36 Light Chain, Quinolone resistance protein NorA
Authors:Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N.
Deposit date:2021-02-09
Release date:2022-04-20
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
4ZIR
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BU of 4zir by Molmil
Crystal structure of EcfAA' heterodimer bound to AMPPNP
Descriptor: CHLORIDE ION, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ...
Authors:Karpowich, N.K, Cocco, N, Song, J.M, Wang, D.N.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:ATP binding drives substrate capture in an ECF transporter by a release-and-catch mechanism.
Nat.Struct.Mol.Biol., 22, 2015
5KC4
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BU of 5kc4 by Molmil
Structure of TmRibU, orthorhombic crystal form
Descriptor: RIBOFLAVIN, Riboflavin transporter RibU, nonyl beta-D-glucopyranoside
Authors:Karpowich, N.K, Wang, D.N, Song, J.M.
Deposit date:2016-06-04
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:An Aromatic Cap Seals the Substrate Binding Site in an ECF-Type S Subunit for Riboflavin.
J.Mol.Biol., 428, 2016
5KC0
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BU of 5kc0 by Molmil
Crystal structure of TmRibU, hexagonal crystal form
Descriptor: RIBOFLAVIN, Riboflavin transporter RibU, nonyl beta-D-glucopyranoside
Authors:Karpowich, N.K, Wang, D.N, Song, J.M.
Deposit date:2016-06-03
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2001 Å)
Cite:An Aromatic Cap Seals the Substrate Binding Site in an ECF-Type S Subunit for Riboflavin.
J.Mol.Biol., 428, 2016
7T9F
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BU of 7t9f by Molmil
Structure of VcINDY-apo
Descriptor: DASS family sodium-coupled anion symporter
Authors:Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N.
Deposit date:2021-12-19
Release date:2022-05-25
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY.
Nat Commun, 13, 2022
7T9G
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BU of 7t9g by Molmil
Structure of VcINDY-Na+
Descriptor: DASS family sodium-coupled anion symporter, SODIUM ION
Authors:Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N.
Deposit date:2021-12-19
Release date:2022-05-25
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY.
Nat Commun, 13, 2022
7EW5
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BU of 7ew5 by Molmil
immune complex of HPV6 L1 pentamer and neutralizing antibody 13H5
Descriptor: Heavy chain of 13H5, Light chain of 13H5, Major capsid protein L1
Authors:Wang, Z.P, Wang, D.N, Gu, Y, Li, S.W.
Deposit date:2021-05-24
Release date:2022-06-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.606 Å)
Cite:structure of HPV6 L1 pentamer in complex with neutralizing antibody 13H5
To Be Published
7F8I
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BU of 7f8i by Molmil
Crystal structure of HPV6 L1 pentamer
Descriptor: Major capsid protein L1
Authors:Wang, Z.P, Wang, D.N, Gu, Y, Li, S.W.
Deposit date:2021-07-02
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.366 Å)
Cite:Crystal structure of HPV6 L1 pentamer
To Be Published
7JSJ
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BU of 7jsj by Molmil
Structure of the NaCT-PF2 complex
Descriptor: (2R)-2-[2-(4-tert-butylphenyl)ethyl]-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
Authors:Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N.
Deposit date:2020-08-14
Release date:2021-02-24
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structure and inhibition mechanism of the human citrate transporter NaCT.
Nature, 591, 2021
7JSK
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BU of 7jsk by Molmil
Structure of the NaCT-Citrate complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, SODIUM ION, ...
Authors:Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N.
Deposit date:2020-08-14
Release date:2021-02-24
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structure and inhibition mechanism of the human citrate transporter NaCT.
Nature, 591, 2021
5KBW
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BU of 5kbw by Molmil
Crystal structure of TmRibU, the riboflavin-binding S subunit from the Thermotoga maritima ECF transporter
Descriptor: RIBOFLAVIN, Riboflavin transporter RibU
Authors:Karpowich, N.K, Wang, D.N, Song, J.M.
Deposit date:2016-06-03
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6093 Å)
Cite:An Aromatic Cap Seals the Substrate Binding Site in an ECF-Type S Subunit for Riboflavin.
J.Mol.Biol., 428, 2016
1PW4
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BU of 1pw4 by Molmil
Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Descriptor: Glycerol-3-phosphate transporter
Authors:Huang, Y, Lemieux, M.J, Song, J, Auer, M, Wang, D.N.
Deposit date:2003-06-30
Release date:2003-08-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and Mechanism of the Glycerol-3-Phosphate Transporter from Escherichia Coli
Science, 301, 2003
3GWV
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BU of 3gwv by Molmil
Leucine transporter LeuT in complex with R-fluoxetine
Descriptor: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ...
Authors:Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
Deposit date:2009-04-01
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
3GWU
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BU of 3gwu by Molmil
Leucine transporter LeuT in complex with sertraline
Descriptor: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, LEUCINE, SODIUM ION, ...
Authors:Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
Deposit date:2009-04-01
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
3GWW
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BU of 3gww by Molmil
Leucine transporter LeuT in complex with S-fluoxetine
Descriptor: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ...
Authors:Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N.
Deposit date:2009-04-01
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
3KLY
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BU of 3kly by Molmil
Pentameric formate channel
Descriptor: Putative formate transporter 1, octyl beta-D-glucopyranoside
Authors:Waight, A.B, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-11-09
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanism of a pentameric formate channel
Nat.Struct.Mol.Biol., 17, 2010
3KLZ
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BU of 3klz by Molmil
Pentameric formate channel with formate bound
Descriptor: FORMIC ACID, Putative formate transporter 1, octyl beta-D-glucopyranoside
Authors:Waight, A.B, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2009-11-09
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of a pentameric formate channel
Nat.Struct.Mol.Biol., 17, 2010
6WW5
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BU of 6ww5 by Molmil
Structure of VcINDY-Na-Fab84 in nanodisc
Descriptor: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DASS family sodium-coupled anion symporter, Fab84 Heavy Chain, ...
Authors:Sauer, D.B, Marden, J, Song, J.M, Koide, A, Koide, S, Wang, D.N.
Deposit date:2020-05-07
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU1
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BU of 6wu1 by Molmil
Structure of apo LaINDY
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU2
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BU of 6wu2 by Molmil
Structure of the LaINDY-malate complex
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WTW
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BU of 6wtw by Molmil
Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate
Descriptor: DASS family sodium-coupled anion symporter
Authors:Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU4
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BU of 6wu4 by Molmil
Structure of the LaINDY-alpha-ketoglutarate complex
Descriptor: DASS family sodium-coupled anion symporter
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WTX
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BU of 6wtx by Molmil
Structure of VcINDY in complex with terephthalate
Descriptor: DASS family sodium-coupled anion symporter, SODIUM ION, terephthalic acid
Authors:Sauer, D.B, Marden, J.J, Wang, D.N.
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020

 

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