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2K7G
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SOLUTION STRUCTURE OF VARV F
Descriptor:Varv peptide F
Authors:Wang, C.K.
Deposit date:2008-08-10
Release date:2009-02-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold
J.Biol.Chem., 284, 2009
2KCG
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SOLUTION STRUCTURE OF CYCLOVIOLACIN O2
Descriptor:Cycloviolacin-O2
Authors:Wang, C.K.
Deposit date:2008-12-22
Release date:2009-07-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.
Biophys.J., 97, 2009
2KCH
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SOLUTION STRUCTURE OF MICELLE-BOUND KALATA B2
Descriptor:Kalata-B2
Authors:Wang, C.K.
Deposit date:2008-12-21
Release date:2009-07-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.
Biophys.J., 97, 2009
2KHB
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SOLUTION STRUCTURE OF LINEAR KALATA B1 (LOOP 6)
Descriptor:Kalata-B1
Authors:Wang, C.K., Craik, D.J.
Deposit date:2009-04-01
Release date:2010-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane
To be Published
2KVX
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SOLUTION STRUCTURE OF KALATA B12
Descriptor:Kalata-B12
Authors:Wang, C.K.
Deposit date:2010-03-29
Release date:2011-03-09
Last modified:2016-06-01
Method:SOLUTION NMR
Cite:The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant.
Biochemistry, 50, 2011
4TTK
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RACEMIC STRUCTURE OF SUNFLOWER TRYPSIN INHIBITOR-1 (SFTI-1)
Descriptor:Sunflower Trypsin Inhibitor-1 (SFTI-1) (D-form)
Authors:Wang, C.K., King, G.J., Craik, D.J.
Deposit date:2014-06-22
Release date:2014-09-10
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.2502 Å)
Cite:Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds.
Angew.Chem.Int.Ed.Engl., 53, 2014
4TTL
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RACEMIC STRUCTURE OF CYCLIC VC1.1 (CVC1.1-1)
Descriptor:Alpha-conotoxin Vc1A
Authors:Wang, C.K., King, G.J., Craik, D.J.
Deposit date:2014-06-22
Release date:2014-09-10
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.7004 Å)
Cite:Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds.
Angew.Chem.Int.Ed.Engl., 53, 2014
4TTM
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RACEMIC STRUCTURE OF KALATA B1 (KB1)
Descriptor:Kalata-B1, D-kalata B1
Authors:Wang, C.K., King, G.J., Craik, D.J.
Deposit date:2014-06-22
Release date:2014-09-10
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.9001 Å)
Cite:Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds.
Angew.Chem.Int.Ed.Engl., 53, 2014
4TTN
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QUASI-RACEMIC STRUCTURE OF [G6A]KALATA B1
Descriptor:Kalata-B1, D-kalata B1, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Wang, C.K., King, G.J., Craik, D.J.
Deposit date:2014-06-22
Release date:2014-09-10
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (1.2507 Å)
Cite:Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds.
Angew.Chem.Int.Ed.Engl., 53, 2014
4TTO
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QUASI-RACEMIC STRUCTURE OF [V25A] KALATA B1
Descriptor:Kalata-B1, D-kalata B1
Authors:Wang, C.K., King, G.J., Craik, D.J.
Deposit date:2014-06-22
Release date:2014-09-10
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.3002 Å)
Cite:Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds.
Angew.Chem.Int.Ed.Engl., 53, 2014
5INZ
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RACEMIC STRUCTURE OF BABOON THETA DEFENSIN-2
Descriptor:Theta defensin-2, L-peptide, D-peptide, ...
Authors:Wang, C.K., King, G.J., Conibear, A.C., Ramos, M.C., Craik, D.J.
Deposit date:2016-03-08
Release date:2016-04-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.447 Å)
Cite:Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties.
J.Am.Chem.Soc., 138, 2016
6DKY
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CRYSTAL STRUCTURE OF RIBIFOLIN, AN ORBITIDE FROM JATROPHA RIBIFOLIA
Descriptor:ILE-LEU-GLY-SER-ILE-ILE-LEU-GLY
Authors:Wang, C.K., Ramalho, S.D., King, G.J., Craik, D.J.
Deposit date:2018-05-31
Release date:2018-11-07
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.239 Å)
Cite:Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
6DKZ
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RACEMIC STRUCTURE OF RIBIFOLIN, AN ORBITIDE FROM JATROPHA RIBIFOLIA
Descriptor:ribifolin
Authors:Wang, C.K., King, G.J., Ramalho, S.D.
Deposit date:2018-05-31
Release date:2018-11-14
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (0.99 Å)
Cite:Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
6DL0
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CRYSTAL STRUCTURE OF POHLIANIN C, AN ORBITIDE FROM JATROPHA POHLIANA
Descriptor:pohlianin C
Authors:Wang, C.K., King, G.J., Ramalho, S.D.
Deposit date:2018-05-31
Release date:2018-11-07
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
6DL1
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RACEMIC STRUCTURE OF JATROPHIDIN, AN ORBITIDE FROM JATROPHA CURCAS
Descriptor:jatrophidin
Authors:Wang, C.K., King, G.J., Ramalho, S.D.
Deposit date:2018-05-31
Release date:2018-11-14
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.029 Å)
Cite:Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
4LRV
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CRYSTAL STRUCTURE OF DNDE FROM ESCHERICHIA COLI B7A INVOLVED IN DNA PHOSPHOROTHIOATION MODIFICATION
Descriptor:DNA sulfur modification protein DndE
Authors:Hu, W., Wang, C.K., Liang, J.D., Zhang, T.L., Yang, M., Hu, Z.P., Wang, Z.J., Lan, W.X., Wu, H.M., Ding, J.P., Wu, G., Deng, Z.X., Cao, C.
Deposit date:2013-07-21
Release date:2013-08-28
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification
Cell Res., 22, 2012
2MN1
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SOLUTION STRUCTURE OF KALATA B1[W23WW]
Descriptor:kalata B1[W23WW]
Authors:Henriques, S.T., Huang, Y.H., Chaousis, S., Wang, C.K., Craik, D.J.
Deposit date:2014-03-26
Release date:2015-05-27
Method:SOLUTION NMR
Cite:Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting.
Chembiochem, 15, 2014
3S63
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SAPOSIN-LIKE PROTEIN NA-SLP-1
Descriptor:Saposin-like protein
Authors:Willis, C., Wang, C.K., Osman, A., Simon, A., Mulvenna, J., Pickering, D., Riboldi-Tunicliffe, A., Jones, M.K., Loukas, A., Hofmann, A.
Deposit date:2011-05-24
Release date:2012-01-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm.
Plos One, 6, 2011
3S64
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SAPOSIN-LIKE PROTEIN AC-SLP-1
Descriptor:Saposin-like protein 1, CITRIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Willis, C., Wang, C.K., Osman, A., Simon, A., Mulvenna, J., Pickering, D., Riboldi-Tunicliffe, A., Jones, M.K., Loukas, A., Hofmann, A.
Deposit date:2011-05-25
Release date:2012-01-18
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm.
Plos One, 6, 2011
3S6S
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ANCYLOSTOMA-SECRETED PROTEIN AC-ASP-7
Descriptor:Ac-ASP-7
Authors:Osman, A., Wang, C.K., Winter, A., Loukas, A., Tribolet, L., Gasser, R., Hofmann, A.
Deposit date:2011-05-26
Release date:2012-04-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions.
Biotechnol Adv, 30
3S6U
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CACLCIUM-BOUND AC-ASP-7
Descriptor:Ac-ASP-7, CALCIUM ION
Authors:Osman, A., Wang, C.K., Winter, A., Loukas, A., Tribolet, L., Gasser, R., Hofmann, A.
Deposit date:2011-05-26
Release date:2012-04-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions.
Biotechnol Adv, 30
3S6V
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MANGANESE-BOUND AC-ASP-7
Descriptor:Ac-ASP-7, MANGANESE (II) ION
Authors:Osman, A., Wang, C.K., Winter, A., Loukas, A., Tribolet, L., Gasser, R., Hofmann, A.
Deposit date:2011-05-26
Release date:2012-04-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions.
Biotechnol Adv, 30
3T82
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES
Descriptor:Carbonic anhydrase 2, ZINC ION, 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-glucopyranose
Authors:Hofmann, A., Wang, C.K.
Deposit date:2011-08-01
Release date:2011-10-19
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.
J.Am.Chem.Soc., 133, 2011
3T83
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES
Descriptor:Carbonic anhydrase 2, ZINC ION, 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-alpha-D-glucopyranose, ...
Authors:Hofmann, A., Wang, C.K.
Deposit date:2011-08-01
Release date:2011-10-19
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.
J.Am.Chem.Soc., 133, 2011
3T84
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES
Descriptor:Carbonic anhydrase 2, ZINC ION, 4-O-acetyl-6-O-sulfamoyl-alpha-D-galactopyranose
Authors:Hofmann, A., Wang, C.K.
Deposit date:2011-08-01
Release date:2011-10-19
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.
J.Am.Chem.Soc., 133, 2011
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