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5I7J
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CRYSTAL STRUCTURE OF HUMAN SPLUNC1 DISULFIDE MUTANT M3 (I76C, V214C)
Descriptor:BPI fold-containing family A member 1
Authors:Walton, W.G., Redinbo, M.R.
Deposit date:2016-02-17
Release date:2016-05-18
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.544 Å)
Cite:Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
Biochemistry, 55, 2016
5I7K
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CRYSTAL STRUCTURE OF HUMAN SPLUNC1 DOLPHIN MUTANT D1 (G58A, S61A, G62E, G63D, G66D, I67T)
Descriptor:BPI fold-containing family A member 1
Authors:Walton, W.G., Redinbo, M.R.
Deposit date:2016-02-17
Release date:2016-05-18
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
Biochemistry, 55, 2016
5I7L
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CRYSTAL STRUCTURE OF SPLUNC1 DISULFIDE MUTANT M2 (A48C, V253C)
Descriptor:BPI fold-containing family A member 1
Authors:Walton, W.G., Redinbo, M.R.
Deposit date:2016-02-17
Release date:2016-05-18
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
Biochemistry, 55, 2016
5UJ6
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CRYSTAL STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, GLYCEROL, ...
Authors:Walton, W.G., Redinbo, M.R.
Deposit date:2017-01-17
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An Atlas of beta-Glucuronidases in the Human Intestinal Microbiome.
Structure, 25, 2017
6D1N
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APO STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1
Descriptor:Beta-galactosidase/beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D1P
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APO STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 3
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D41
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BACTERIODES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO D-GLUCARO-1,5-LACTONE
Descriptor:Beta-galactosidase/beta-glucuronidase, GLYCEROL, CHLORIDE ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-17
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D50
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BACTEROIDES UNIFORMS BETA-GLUCURONIDASE 2 BOUND TO D-GLUCARO-1,5-LACTONE
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, CALCIUM ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-19
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D6W
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BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO GLUCURONATE
Descriptor:Beta-galactosidase/beta-glucuronidase, D-GLUCURONIC ACID, GLYCEROL, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-23
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D7F
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BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO THIOPHENYL-BETA-D-GLUCURONIDE
Descriptor:Beta-galactosidase/beta-glucuronidase, phenyl 1-thio-beta-D-glucopyranosiduronic acid, CHLORIDE ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-24
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D89
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BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 WITH N-TERMINAL LOOP DELETION
Descriptor:Beta-galactosidase/beta-glucuronidase, CITRIC ACID, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8G
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D341A D367A CALCIUM BINDING MUTANT OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 2
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8K
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BACTEROIDES MULTIPLE SPECIES BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolase family 2, sugar binding domain protein
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6NCW
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CRYSTAL STRUCTURE OF A GH2 BETA-GALACTURONIDASE FROM EISENBERGIELLA TAYI BOUND TO GLYCEROL
Descriptor:Beta-galacturonidase, CHLORIDE ION, GLYCEROL
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCX
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CRYSTAL STRUCTURE OF GH2 BETA-GALACTURONIDASE FROM EISENBERGIELLA TAYI BOUND TO GALACTURONATE
Descriptor:Beta-galacturonidase, ALPHA-D-GALACTOPYRANURONIC ACID, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCY
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CRYSTAL STRUCTURE OF HYBRID BETA-GLUCURONIDASE/BETA-GALACTURONIDASE FROM FUSICATENIBACTER SACCHARIVORANS
Descriptor:Beta-glucuronidase, NICKEL (II) ION, GLYCEROL, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
6NCZ
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CRYSTAL STRUCTURE OF HYBRID BETA-GLUCURONIDASE/BETA-GALACTURONIDASE FROM FUSICATENIBACTER SACCHARIVORANS BOUND TO PHENYL-THIO-BETA-D-GLUCURONIDE
Descriptor:Beta-glucuronidase, phenyl 1-thio-beta-D-glucopyranosiduronic acid, GLYCEROL
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-12-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
Biochemistry, 58, 2019
4K59
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA RSMF
Descriptor:RNA BINDING PROTEIN RsmF
Authors:Betts, L., Walton, W.G., Redinbo, M.R.
Deposit date:2013-04-14
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:An unusual CsrA family member operates in series with RsmA to amplify posttranscriptional responses in Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KGH
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CRYSTAL STRUCTURE OF HUMAN SPLUNC1 LACKING THE SECRETION SIGNAL SEQUENCE
Descriptor:BPI fold-containing family A member 1, NITRATE ION, AMMONIUM ION, ...
Authors:Betts, L., Walton, W.G.
Deposit date:2013-04-29
Release date:2013-09-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KGO
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CRYSTAL STRUCTURE OF DOUBLE LEUCINE TO METHIONINE MUTANT HUMAN SPLUNC1 LACKING THE SECRETION SIGNAL SEQUENCE
Descriptor:BPI fold-containing family A member 1
Authors:Betts, L., Walton, W.G.
Deposit date:2013-04-29
Release date:2013-09-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
Proc.Natl.Acad.Sci.USA, 110, 2013
6BJQ
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO GLUCURONIC ACID
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase, BETA-D-GLUCOPYRANURONIC ACID
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-06
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BJW
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-07
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BO6
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO UNC4917 GLUCURONIC ACID CONJUGATE
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase, 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-18
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6D4O
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO AN AMOXAPINE-GLUCURONIDE CONJUGATE
Descriptor:Beta-glucuronidase, (5aR,9aR)-2-chloro-11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5a,6,9,9a-tetrahydrodibenzo[b,f][1,4]oxazepine, CHLORIDE ION, ...
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2018-04-18
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6ECA
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LACTOBACILLUS RHAMNOSUS BETA-GLUCURONIDASE
Descriptor:Beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Biernat, K.A., Pellock, S.J., Bhatt, A.P., Bivins, M.M., Walton, W.G., Tran, B.N.T., Wei, L., Snider, M.C., Cesmat, A.P., Tripathy, A., Erie, D.A., Redinbo, M.R.R.
Deposit date:2018-08-07
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.853 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
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