Author results

4BN7
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NITROREDUCTASE CIND FROM LACTOCOCCUS LACTIS IN COMPLEX WITH 2,6- DICHLOROPHENOLINDOPHENOL
Descriptor:COPPER INDUCED NITROREDUCTASE D, FLAVIN MONONUCLEOTIDE, 2,6-bis(chloranyl)-4-[(4-hydroxyphenyl)amino]phenol
Authors:Waltersperger, S., Baumgartner, R., Oberholzer, A.E.
Deposit date:2013-05-13
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.723 Å)
Cite:Nitroreductase Cind from Lactococcus Lactis
To be Published
4BNB
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NITROREDUCTASE CIND FROM LACTOCOCCUS LACTIS IN COMPLEX WITH 4- NITROQUINOLINE 1-OXIDE
Descriptor:COPPER INDUCED NITROREDUCTASE D, FLAVIN MONONUCLEOTIDE, 4-NITROQUINOLINE 1-OXIDE
Authors:Waltersperger, S., Oberholzer, A.E., Baumgartner, R.
Deposit date:2013-05-13
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.478 Å)
Cite:Nitroreductase Cind from Lactococcus Lactis in Complex with 2 4-Nitroquinoline 1-Oxidenone
To be Published
5I6A
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BICYCLO[3.3.2]DECAPEPTIDE
Descriptor:ALA-PHE-GLY-LYD-VAL-PHE-PRO-GLN-ALA-GLY, DIMETHYL SULFOXIDE
Authors:Bartoloni, M., Waltersperger, S., Bumann, M., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2016-02-16
Release date:2016-03-09
Method:X-RAY DIFFRACTION (0.813 Å)
Cite:Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide
Arkivoc, 2014, 2014
3VGX
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STRUCTURE OF GP41 T21/CP621-652
Descriptor:Envelope glycoprotein gp160, ACETIC ACID, GLYCEROL
Authors:Yao, X., Waltersperger, S., Wang, M., Cui, S.
Deposit date:2011-08-22
Release date:2012-04-25
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
J.Biol.Chem., 287, 2012
3VGY
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P321
Descriptor:Envelope glycoprotein gp160, CP32M, SULFATE ION
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2011-08-22
Release date:2012-06-13
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.034 Å)
Cite:Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VH7
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P21
Descriptor:Envelope glycoprotein gp160, CP32M, MAGNESIUM ION
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2011-08-23
Release date:2012-06-13
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.019 Å)
Cite:Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VIE
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HIV-GP41 FUSION INHIBITOR SIFUVIRTIDE
Descriptor:Envelope glycoprotein gp160, Sifuvirtide
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2011-09-29
Release date:2012-01-18
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
J.Biol.Chem., 287, 2012
3VTP
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HIV FUSION INHIBITOR MT-C34
Descriptor:Transmembrane protein gp41
Authors:Yao, X., Waltersperger, S., Wang, M., Cui, S.
Deposit date:2012-06-02
Release date:2012-08-22
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The M-T hook structure is critical for design of HIV-1 fusion inhibitors.
J.Biol.Chem., 287, 2012
3VTQ
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NOVEL HIV FUSION INHIBITOR
Descriptor:Envelope glycoprotein gp160, fusion inhibitor MT-Sifuvirtide
Authors:Yao, X., Waltersperger, S., Wang, M., Cui, S.
Deposit date:2012-06-02
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystal structure of a novel HIV fusion inhibitor
To be Published
3VU5
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SHORT PEPTIDE HIV ENTRY INHIBITOR SC22EK
Descriptor:Transmembrane protein gp41, SC22, SULFATE ION, ...
Authors:Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
Deposit date:2012-06-19
Release date:2012-12-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VU6
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SHORT PEPTIDE HIV ENTRY INHIBITOR MT-SC22EK WITH A M-T HOOK
Descriptor:Transmembrane protein gp41, MTSC22, SULFATE ION
Authors:Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
Deposit date:2012-06-19
Release date:2012-12-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.324 Å)
Cite:Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VWB
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN (SE-MET DERIVATIVE) COMPLEXED WITH THE CIS-ACTING SITE (5-BRU MODIFICATIONS) UPSTREAM ICSB PROMOTER
Descriptor:Virulence regulon transcriptional activator virB, DNA (26-MER)
Authors:Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-08-21
Release date:2013-08-21
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.416 Å)
Cite:Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
3W19
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POTENT HIV FUSION INHIBITOR CP32M-2
Descriptor:Transmembrane protein gp41, fusion inhibitor CP32M-2
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-11-13
Release date:2013-12-11
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:Optimization of novel anti-HIV fusion inhibitor
To be Published
3W2A
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSP PROMOTER
Descriptor:Virulence regulon transcriptional activator VirB, DNA (31-mer)
Authors:Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-11-27
Release date:2013-09-04
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.775 Å)
Cite:Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
3W3C
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSB PROMOTER
Descriptor:Virulence regulon transcriptional activator VirB, DNA (26-MER)
Authors:Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-12-19
Release date:2013-09-04
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
4I2L
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NEW HIV ENTRY INHIBITOR MTSFT/T23 COMPLEX
Descriptor:GP41, inhibitor MTSFT
Authors:Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
Deposit date:2012-11-22
Release date:2014-01-22
Method:X-RAY DIFFRACTION (1.426 Å)
Cite:Potent antiviral activity of the novel HIV entry inhibitor MTSFT
To be Published
4PGO
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PF0907 FROM PYROCOCCUS FURIOSUS SOLVED BY SULFUR SAD USING SWISS LIGHT SOURCE DATA
Descriptor:Uncharacterized protein, CHLORIDE ION
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-05-02
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4PII
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PF0907 FROM PYROCOCCUS FURIOSUS SOLVED BY SULFUR SAD USING SWISS LIGHT SOURCE DATA
Descriptor:N-glycosylase/DNA lyase, CHLORIDE ION, IMIDAZOLE
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-05-08
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4TN8
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS THIOREDOXIN SOLVED BY SULFUR SAD USING SWISS LIGHT SOURCE DATA
Descriptor:Thioredoxin, CHLORIDE ION
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-06-03
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4TNO
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HYPOTHETICAL PROTEIN PF1117 FROM PYROCOCCUS FURIOSUS: STRUCTURE SOLVED BY SULFUR-SAD USING SWISS LIGHT SOURCE DATA
Descriptor:CRISPR-associated endoribonuclease Cas2, CHLORIDE ION
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-06-04
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WBX
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CONSERVED HYPOTHETICAL PROTEIN PF1771 FROM PYROCOCCUS FURIOSUS SOLVED BY SULFUR SAD USING SWISS LIGHT SOURCE DATA
Descriptor:2-keto acid:ferredoxin oxidoreductase subunit alpha
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-09-04
Release date:2014-12-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4BN6
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NITROREDUCTASE CIND FROM LACTOCOCCUS LACTIS IN COMPLEX WITH CHLORAMPHENICOL
Descriptor:COPPER INDUCED NITROREDUCTASE D, FLAVIN MONONUCLEOTIDE, CHLORAMPHENICOL
Authors:Oberholzer, A.E., Baumgartner, R., Waltersperger, S.
Deposit date:2013-05-13
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.462 Å)
Cite:Nitroreductase Cind from Lactococcus Lactis in Complex with Chloramphenicol
To be Published
4BN8
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NITROREDUCTASE CIND FROM LACTOCOCCUS LACTIS IN COMPLEX WITH 4- NITROPHENOL
Descriptor:COPPER INDUCED NITROREDUCTASE D, FLAVIN MONONUCLEOTIDE, P-NITROPHENOL
Authors:Oberholzer, A.E., Waltersperger, S., Baumgartner, R.
Deposit date:2013-05-13
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Nitroreductase Cind from Lactococcus Lactis
To be Published
4BN9
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NITROREDUCTASE CIND FROM LACTOCOCCUS LACTIS IN COMPLEX WITH NICOTINIC ACID
Descriptor:COPPER INDUCED NITROREDUCTASE D, NICOTINIC ACID, FLAVIN MONONUCLEOTIDE
Authors:Baumgartner, R., Waltersperger, S., Oberholzer, A.E.
Deposit date:2013-05-13
Release date:2014-05-28
Method:X-RAY DIFFRACTION (2.084 Å)
Cite:Nitroreductase Cind from Lactococcus Lactis
To be Published
2WQF
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CRYSTAL STRUCTURE OF THE NITROREDUCTASE CIND FROM LACTOCOCCUS LACTIS IN COMPLEX WITH FMN
Descriptor:COPPER INDUCED NITROREDUCTASE D, FLAVIN MONONUCLEOTIDE
Authors:Waltersperger, S.M., Oberholzer, A.E., Solioz, M., Baumann, U.
Deposit date:2009-08-20
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure and Function of Cind (Ytjd) of Lactococcus Lactis, a Copper-Induced Nitroreductase Involved in Defense Against Oxidative Stress.
J.Bacteriol., 192, 2010
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