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1INR
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BU of 1inr by Molmil
CYTOKINE SYNTHESIS
Descriptor: INTERLEUKIN-10
Authors:Walter, M.R.
Deposit date:1995-07-31
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of interleukin 10 reveals an interferon gamma-like fold.
Biochemistry, 34, 1995
2INT
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BU of 2int by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-4
Descriptor: INTERLEUKIN-4
Authors:Walter, M.R, Cook, W.J, Zhao, B.G, Cameron Junior, R, Ealick, S.E, Walter Junior, R.L, Reichert, P, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E.
Deposit date:1993-07-22
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of recombinant human interleukin-4.
J.Biol.Chem., 267, 1992
1CSG
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BU of 1csg by Molmil
Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor
Descriptor: Granulocyte-macrophage colony-stimulating factor
Authors:Walter, M.R, Cook, W.J, Ealick, S.E.
Deposit date:1992-11-23
Release date:1993-10-31
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.
J.Mol.Biol., 224, 1992
1TPT
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BU of 1tpt by Molmil
THREE-DIMENSIONAL STRUCTURE OF THYMIDINE PHOSPHORYLASE FROM ESCHERICHIA COLI AT 2.8 ANGSTROMS RESOLUTION
Descriptor: SULFATE ION, THYMIDINE PHOSPHORYLASE, THYMINE
Authors:Walter, M.R, Cook, W.J, Cole, L.B, Short, S.A, Koszalka, G.W, Krenitsky, T.A, Ealick, S.E.
Deposit date:1990-06-14
Release date:1991-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution.
J.Biol.Chem., 265, 1990
1RH2
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BU of 1rh2 by Molmil
RECOMBINANT HUMAN INTERFERON-ALPHA 2B
Descriptor: INTERFERON-ALPHA 2B, ZINC ION
Authors:Walter, M.R.
Deposit date:1996-11-07
Release date:1997-11-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography.
Structure, 4, 1996
1AZY
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BU of 1azy by Molmil
STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE
Descriptor: THYMIDINE PHOSPHORYLASE
Authors:Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E.
Deposit date:1997-11-24
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
1B5L
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BU of 1b5l by Molmil
OVINE INTERFERON TAU
Descriptor: INTERFERON TAU, SULFATE ION
Authors:Radhakrishnan, R, Walter, L.J, Subramaniam, P.S, Johnson, H.J, Walter, M.R.
Deposit date:1999-01-07
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of ovine interferon-tau at 2.1 A resolution.
J.Mol.Biol., 286, 1999
1LK3
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BU of 1lk3 by Molmil
ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT
Descriptor: 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10
Authors:Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R.
Deposit date:2002-04-23
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography.
Structure, 10, 2002
3BES
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BU of 3bes by Molmil
Structure of a Poxvirus ifngbp/ifng Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon gamma, Interferon-gamma binding protein C4R, ...
Authors:Nuara, A.A, Walter, M.R.
Deposit date:2007-11-20
Release date:2008-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and mechanism of IFN-gamma antagonism by an orthopoxvirus IFN-gamma-binding protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1CTR
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BU of 1ctr by Molmil
DRUG BINDING BY CALMODULIN: CRYSTAL STRUCTURE OF A CALMODULIN-TRIFLUOPERAZINE COMPLEX
Descriptor: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CALMODULIN
Authors:Cook, W.J, Walter, L.J, Walter, M.R.
Deposit date:1994-09-21
Release date:1994-12-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex.
Biochemistry, 33, 1994
8FAX
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BU of 8fax by Molmil
Fab 1249A8-MERS Stem Helix Complex
Descriptor: 1249A8-HC, 1249A8-LC, CHLORIDE ION, ...
Authors:Deshpande, A, Schormann, N, Piepenbrink, M.S, Martinez-Sobrido, L, Kobie, J.J, Walter, M.R.
Deposit date:2022-11-28
Release date:2023-05-03
Last modified:2023-07-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and epitope of a neutralizing monoclonal antibody that targets the stem helix of beta coronaviruses.
Febs J., 290, 2023
3DGC
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BU of 3dgc by Molmil
Structure of IL-22/IL-22R1
Descriptor: ACETATE ION, CHLORIDE ION, Interleukin-22, ...
Authors:Jones, B.C, Logsdon, N.J, Walter, M.R.
Deposit date:2008-06-13
Release date:2008-07-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain.
Structure, 16, 2008
3LQM
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BU of 3lqm by Molmil
Structure of the IL-10R2 Common Chain
Descriptor: GLYCEROL, Interleukin-10 receptor subunit beta, SULFATE ION
Authors:Yoon, S.I, Walter, M.R.
Deposit date:2010-02-09
Release date:2010-05-26
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure and mechanism of receptor sharing by the IL-10R2 common chain.
Structure, 18, 2010
1J7V
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BU of 1j7v by Molmil
HUMAN IL-10 / IL-10R1 COMPLEX
Descriptor: INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN
Authors:Josephson, K, Logsdon, N, Walter, M.R.
Deposit date:2001-05-18
Release date:2001-09-19
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.
Immunity, 15, 2001
1LQS
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BU of 1lqs by Molmil
CRYSTAL STRUCTURE OF HUMAN CYTOMEGALOVIRUS IL-10 BOUND TO SOLUBLE HUMAN IL-10R1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN, INTERLEUKIN-10-LIKE PROTEIN
Authors:Jones, B.C, Logsdon, N.J, Josephson, K, Cook, J, Barry, P.A, Walter, M.R.
Deposit date:2002-05-13
Release date:2002-07-17
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1.
Proc.Natl.Acad.Sci.USA, 99, 2002
4DOH
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BU of 4doh by Molmil
IL20/IL201/IL20R2 Ternary Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-20, Interleukin-20 receptor subunit alpha, ...
Authors:Logsdon, N.J, Walter, M.R.
Deposit date:2012-02-09
Release date:2012-07-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.
Proc.Natl.Acad.Sci.USA, 109, 2012
1EKU
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BU of 1eku by Molmil
CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA
Descriptor: Interferon gamma, SULFATE ION
Authors:Landar, A, Curry, B, Parker, M.H, DiGiacomo, R, Indelicato, S.R, Walter, M.R.
Deposit date:2000-03-09
Release date:2000-09-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.
J.Mol.Biol., 299, 2000
2TPT
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BU of 2tpt by Molmil
STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE
Descriptor: SULFATE ION, THYMIDINE PHOSPHORYLASE
Authors:Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E.
Deposit date:1997-11-24
Release date:1999-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
1Y6M
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BU of 1y6m by Molmil
Crystal structure of Epstein-Barr virus IL-10 complexed with the soluble IL-10R1 chain
Descriptor: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
Authors:Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
Deposit date:2004-12-06
Release date:2005-05-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1Y6K
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BU of 1y6k by Molmil
Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain
Descriptor: Interleukin-10, Interleukin-10 receptor alpha chain
Authors:Yoon, S.I, Jones, B.C, Josepson, K, Logsdon, N.J, Walter, M.R.
Deposit date:2004-12-06
Release date:2005-12-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1Y6N
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BU of 1y6n by Molmil
Crystal structure of Epstein-Barr virus IL-10 mutant (A87I) complexed with the soluble IL-10R1 chain
Descriptor: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
Authors:Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
Deposit date:2004-12-06
Release date:2005-05-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1YKB
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BU of 1ykb by Molmil
Crystal Structure of Insect Cell Expressed IL-22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, T, Logsdon, N.J, Walter, M.R.
Deposit date:2005-01-17
Release date:2005-07-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of insect-cell-derived IL-22.
Acta Crystallogr.,Sect.D, 61, 2005
1OTP
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BU of 1otp by Molmil
STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE
Descriptor: THYMIDINE PHOSPHORYLASE
Authors:Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E.
Deposit date:1997-11-09
Release date:1998-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
2H24
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BU of 2h24 by Molmil
Crystal structure of human IL-10
Descriptor: Interleukin-10
Authors:Yoon, S.I, Walter, M.R.
Deposit date:2006-05-18
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.
J.Biol.Chem., 281, 2006
1A29
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BU of 1a29 by Molmil
CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:2 COMPLEX)
Descriptor: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CALMODULIN
Authors:Bocskei, Zs, Harmat, V, Vertessy, B.G, Ovadi, J, Naray-Szabo, G.
Deposit date:1998-01-19
Release date:1998-09-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Simultaneous binding of drugs with different chemical structures to Ca2+-calmodulin: crystallographic and spectroscopic studies.
Biochemistry, 37, 1998

 

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