Author results

1CC0
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CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX
Descriptor:transforming protein rhoA, rho GDP dissociation inhibitor alpha, MAGNESIUM ION, ...
Authors:Longenecker, K.L., Read, P., Derewenda, U., Dauter, Z., Garrard, S., Walker, L., Somlyo, A.V., Somlyo, A.P., Nakamoto, R.K., Derewenda, Z.S.
Deposit date:1999-03-03
Release date:2000-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
5MJY
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CRYSTAL STRUCTURE OF THE HIS DOMAIN PROTEIN TYROSINE PHOSPHATASE (HD-PTP/PTPN23) BRO1 DOMAIN (SARA COMPLEX STRUCTURE)
Descriptor:Tyrosine-protein phosphatase non-receptor type 23, Zinc finger FYVE domain-containing protein 9
Authors:Levy, C., Gahloth, D.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
5MJZ
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CRYSTAL STRUCTURE OF THE HIS DOMAIN PROTEIN TYROSINE PHOSPHATASE (HD-PTP/PTPN23) BRO1 DOMAIN (APO STRUCTURE)
Descriptor:Tyrosine-protein phosphatase non-receptor type 23
Authors:Levy, C., Gahloth, D.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.867 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
5MK0
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CRYSTAL STRUCTURE OF THE HIS DOMAIN PROTEIN TYROSINE PHOSPHATASE (HD-PTP/PTPN23) BRO1 DOMAIN (ENDOFIN PEPTIDE COMPLEX)
Descriptor:Tyrosine-protein phosphatase non-receptor type 23, Zinc finger FYVE domain-containing protein 16
Authors:Levy, C., Gahloth, D.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.765 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
5MK1
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CRYSTAL STRUCTURE OF THE HIS DOMAIN PROTEIN TYROSINE PHOSPHATASE (HD-PTP/PTPN23) BRO1 DOMAIN (CHMP4A PEPTIDE COMPLEX STRUCTURE)
Descriptor:Tyrosine-protein phosphatase non-receptor type 23, Charged multivesicular body protein 4a
Authors:Levy, C., Gahloth, D.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
5MK2
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CRYSTAL STRUCTURE OF THE HIS DOMAIN PROTEIN TYROSINE PHOSPHATASE (HD-PTP/PTPN23) BRO1 DOMAIN (CHMP4B PEPTIDE COMPLEX STRUCTURE)
Descriptor:Tyrosine-protein phosphatase non-receptor type 23, Charged multivesicular body protein 4b
Authors:Levy, C., Gahloth, D.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
5MK3
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CRYSTAL STRUCTURE OF THE HIS DOMAIN PROTEIN TYROSINE PHOSPHATASE (HD-PTP/PTPN23) BRO 1 DOMAIN (CHMP4C PEPTIDE COMPLEX STRUCTURE)
Descriptor:Tyrosine-protein phosphatase non-receptor type 23, Charged multivesicular body protein 4c
Authors:Levy, C.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
3COH
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CRYSTAL STRUCTURE OF AURORA-A IN COMPLEX WITH A PENTACYCLIC INHIBITOR
Descriptor:Serine/threonine-protein kinase 6, 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one
Authors:Wiesmann, C., Raswson, T.E., Cochran, A.G.
Deposit date:2008-03-28
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability.
J.Med.Chem., 51, 2008
3H0Y
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AURORA A IN COMPLEX WITH A BISANILINOPYRIMIDINE
Descriptor:Serine/threonine-protein kinase 6, 2-chloro-N-[4-({5-fluoro-2-[(4-hydroxyphenyl)amino]pyrimidin-4-yl}amino)phenyl]benzamide, SULFATE ION
Authors:Wiesmann, C., Ultsch, M.H., Cochran, A.G.
Deposit date:2009-04-10
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
J.Med.Chem., 52, 2009
3H0Z
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AURORA A IN COMPLEX WITH A BISANILINOPYRIMIDINE
Descriptor:Serine/threonine-protein kinase 6, 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-N-(2-chlorophenyl)benzamide
Authors:Wiesmann, C., Ultsch, M.H., Cochran, A.G.
Deposit date:2009-04-10
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
J.Med.Chem., 52, 2009
3H10
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AURORA A INHIBITOR COMPLEX
Descriptor:Serine/threonine-protein kinase 6, 9-chloro-7-(2,6-difluorophenyl)-N-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5H-pyrimido[5,4-d][2]benzazepin-2-amine
Authors:Wiesmann, C., Ultsch, M.H., Cochran, A.G.
Deposit date:2009-04-10
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
J.Med.Chem., 52, 2009
5K59
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CRYSTAL STRUCTURE OF LUKGH FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH A NEUTRALISING ANTIBODY
Descriptor:Uncharacterized leukocidin-like protein 2, Uncharacterized leukocidin-like protein 1, Fab heavy chain, ...
Authors:Welin, M., Logan, D.T., Badarau, A., Mirkina, I., Zauner, G., Dolezilkova, I., Nagy, E.
Deposit date:2016-05-23
Release date:2016-08-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
Mabs, 8, 2016