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6OA9
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CDC48-NPL4 COMPLEX PROCESSING POLY-UBIQUITINATED SUBSTRATE IN THE PRESENCE OF ATP
Descriptor:Cell division control protein 48, Ubiquitin, Nuclear protein localization protein 4, ...
Authors:Twomey, E.C., Ji, Z., Wales, T.E., Bodnar, N.O., Engen, J.R., Rapoport, T.A.
Deposit date:2019-03-15
Release date:2019-07-03
Last modified:2019-08-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.
Science, 365, 2019
6OAA
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CDC48-NPL4 COMPLEX PROCESSING POLY-UBIQUITINATED SUBSTRATE IN THE PRESENCE OF ADP-BEFX, STATE 1
Descriptor:Cell division control protein 48, Nuclear protein localization protein 4, Ubiquitin, ...
Authors:Twomey, E.C., Ji, Z., Wales, T.E., Bodnar, N.O., Engen, J.R., Rapoport, T.A.
Deposit date:2019-03-15
Release date:2019-07-03
Last modified:2019-08-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.
Science, 365, 2019
6OAB
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CDC48-NPL4 COMPLEX PROCESSING POLY-UBIQUITINATED SUBSTRATE IN THE PRESENCE OF ADP-BEFX, STATE 2
Descriptor:Cell division control protein 48, poly(alanine) substrate, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Twomey, E.C., Ji, Z., Wales, T.E., Bodnar, N.O., Engen, J.R., Rapoport, T.A.
Deposit date:2019-03-15
Release date:2019-07-03
Last modified:2019-08-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.
Science, 365, 2019
6QA2
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R80A MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Nucleoside diphosphate kinase, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Dautant, A., Henri, J., Wales, T.E., Meyer, P., Engen, J.R., Georgescauld, F.
Deposit date:2018-12-18
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange.
Biochemistry, 58, 2019
3V79
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STRUCTURE OF HUMAN NOTCH1 TRANSCRIPTION COMPLEX INCLUDING CSL, RAM, ANK, AND MAML-1 ON HES-1 PROMOTER DNA SEQUENCE
Descriptor:Neurogenic locus notch homolog protein 1, Recombining binding protein suppressor of hairless, Mastermind-like protein 1, ...
Authors:Nam, Y., Sliz, P., Blacklow, S.
Deposit date:2011-12-20
Release date:2012-02-15
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes.
Structure, 20, 2012
6BOF
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CRYSTAL STRUCTURE OF KRAS A146T-GDP DEMONSTRATING OPEN SWITCH 1 CONFORMATION
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE
Authors:Bera, A.K., Yan, W., Westover, K.D.
Deposit date:2017-11-20
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Tissue-Specific Oncogenic Activity of KRASA146T.
Cancer Discov, 9, 2019
6CDD
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NPL4 ZINC FINGER AND MPN DOMAINS (CHAETOMIUM THERMOPHILUM)
Descriptor:Npl4 zinc finger, ZINC ION
Authors:Bodnar, N.O., Rapoport, T.A.
Deposit date:2018-02-08
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.582337 Å)
Cite:Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
6CHS
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CDC48-NPL4 COMPLEX IN THE PRESENCE OF ATP-GAMMA-S
Descriptor:Npl4, Putative cell division control protein, ZINC ION, ...
Authors:Kim, K.H., Bodnar, N.O., Walz, T., Rapoport, T.A.
Deposit date:2018-02-22
Release date:2018-07-04
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
6MQG
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CRYSTAL STRUCTURE OF KRAS V14I-GDP DEMONSTRATING OPEN SWITCH 1 CONFORMATION - FORM 1
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE
Authors:Bera, A.K., Westover, K.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of the atypical activation mechanism of KRAS V14I.
J.Biol.Chem., 2019
6MQN
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CRYSTAL STRUCTURE OF KRAS V14I-GDP DEMONSTRATING DISORDER SWITCH 1 CONFORMATION - FORM 2
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE
Authors:Bera, A.K., Westover, K.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of the atypical activation mechanism of KRAS V14I.
J.Biol.Chem., 2019