Author results

1SHA
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES
Descriptor:V-SRC SH2 DOMAIN, PHOSPHOPEPTIDE A
Authors:Waksman, G., Kuriyan, J.
Deposit date:1992-08-18
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides.
Nature, 358, 1992
1SHB
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES
Descriptor:V-SRC SH2 DOMAIN, PHOSPHOPEPTIDE B
Authors:Waksman, G., Kuriyan, J.
Deposit date:1992-08-18
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides.
Nature, 358, 1992
1SPR
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BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS
Descriptor:SRC TYROSINE KINASE SH2 DOMAIN, PHOSPHATE ION
Authors:Waksman, G., Kuriyan, J.
Deposit date:1993-03-05
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
Cell(Cambridge,Mass.), 72, 1993
1SPS
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BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS
Descriptor:SRC SH2 DOMAIN, PEPTIDE YEEI
Authors:Waksman, G., Kuriyan, J.
Deposit date:1993-03-05
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
Cell(Cambridge,Mass.), 72, 1993
1TDE
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE REFINED AT 2 ANGSTROM RESOLUTION: IMPLICATIONS FOR A LARGE CONFORMATIONAL CHANGE DURING CATALYSIS
Descriptor:THIOREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Waksman, G., Krishna, T.S.R., Williams Junior, C.H., Kuriyan, J.
Deposit date:1994-01-14
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
J.Mol.Biol., 236, 1994
1TDF
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE REFINED AT 2 ANGSTROM RESOLUTION: IMPLICATIONS FOR A LARGE CONFORMATIONAL CHANGE DURING CATALYSIS
Descriptor:THIOREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Waksman, G., Krishna, T.S.R., Williams Junior, C.H., Kuriyan, J.
Deposit date:1994-01-14
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
J.Mol.Biol., 236, 1994
2YPW
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ATOMIC MODEL FOR THE N-TERMINUS OF TRAO FITTED IN THE FULL-LENGTH STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX
Descriptor:TRAO
Authors:Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
Deposit date:2012-11-02
Release date:2013-04-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (12.4 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
3ZBI
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FITTING RESULT IN THE O-LAYER OF THE SUBNANOMETER STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX DIGESTED WITH ELASTASE
Descriptor:TRAF PROTEIN, TRAO PROTEIN, TRAN PROTEIN
Authors:Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
Deposit date:2012-11-10
Release date:2013-04-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
5NNY
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CRYSTAL STRUCTURE OF THE PHOSPHATASE DOMAIN FROM THE LEGIONELLA EFFECTOR WIPB
Descriptor:WipB
Authors:Pinotsis, N., Waksman, G., Prevost, M.S.
Deposit date:2017-04-10
Release date:2017-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery.
Sci Rep, 7, 2017
1J8R
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BINARY COMPLEX OF THE PAPG RECEPTOR-BINDING DOMAIN BOUND TO GBO4 RECEPTOR
Descriptor:PYELONEPHRITIC ADHESIN, N-ACETYL-D-GALACTOSAMINE, ALPHA D-GALACTOSE, ...
Authors:Dodson, K.W., Pinkner, J.S., Rose, T., Magnusson, G., Hultgren, S.J., Waksman, G., Midwest Center for Structural Genomics (MCSG)
Deposit date:2001-05-22
Release date:2001-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.
Cell(Cambridge,Mass.), 105, 2001
1J8S
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PAPG ADHESIN RECEPTOR BINDING DOMAIN-UNBOUND FORM
Descriptor:PYELONEPHRITIC ADHESIN
Authors:Dodson, K.W., Pinkner, J.S., Rose, T., Magnusson, G., Hultgren, S.J., Waksman, G.
Deposit date:2001-05-22
Release date:2001-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.
Cell(Cambridge,Mass.), 105, 2001
1KA8
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CRYSTAL STRUCTURE OF THE PHAGE P4 ORIGIN-BINDING DOMAIN
Descriptor:putative P4-specific DNA primase
Authors:Yeo, H.J., Ziegelin, G., Korolev, S., Calendar, R., Lanka, E., Waksman, G.
Deposit date:2001-10-31
Release date:2002-04-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Phage P4 origin-binding domain structure reveals a mechanism for regulation of DNA-binding activity by homo- and heterodimerization of winged helix proteins.
Mol.Microbiol., 43, 2002
2BHV
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STRUCTURE OF COMB10 OF THE COM TYPE IV SECRETION SYSTEM OF HELICOBACTER PYLORI
Descriptor:COMB10
Authors:Terradot, L., Oomen, C., Bayliss, R., Leonard, G., Waksman, G.
Deposit date:2005-01-18
Release date:2005-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of Two Core Subunits of the Bacterial Type Iv Secretion System, Virb8 from Brucella Suis and Comb10 from Helicobacter Pylori
Proc.Natl.Acad.Sci.USA, 102, 2005
2GR7
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HIA 992-1098
Descriptor:Adhesin, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Meng, G., Waksman, G.
Deposit date:2006-04-23
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter.
Embo J., 25, 2006
2GR8
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HIA 1022-1098
Descriptor:Adhesin
Authors:Meng, G., Waksman, G.
Deposit date:2006-04-23
Release date:2006-05-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter.
Embo J., 25, 2006
2W07
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STRUCTURAL DETERMINANTS OF POLYMERIZATION REACTIVITY OF THE P PILUS ADAPTOR SUBUNIT PAPF
Descriptor:CHAPERONE PROTEIN PAPD, MINOR PILIN SUBUNIT PAPF, SULFATE ION
Authors:Verger, D., Rose, R.J., Paci, E., Costakes, G., Daviter, T., Hultgren, S., Remaut, H., Ashcroft, A.E., Radford, S.E., Waksman, G.
Deposit date:2008-08-12
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Polymerization Reactivity of the P Pilus Adaptor Subunit Papf.
Structure, 16, 2008
2XG4
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E. COLI P PILUS CHAPERONE-SUBUNIT COMPLEX PAPD-PAPH BOUND TO PILUS BIOGENESIS INHIBITOR, PILICIDE 2C
Descriptor:CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, ...
Authors:Remaut, H., Phan, G., Buelens, F., Chorell, E., Pinkner, J.S., Edvinsson, S., Almqvist, F., Hultgren, S.J., Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
2XG5
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E. COLI P PILUS CHAPERONE-SUBUNIT COMPLEX PAPD-PAPH BOUND TO PILUS BIOGENESIS INHIBITOR, PILICIDE 5D
Descriptor:CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, GLYCEROL, ...
Authors:Remaut, H., Phan, G., Buelens, F., Chorell, E., Pinkner, J.S., Edvinsson, S., Almqvist, F., Hultgren, S.J., Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
3EMF
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CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE HIABD2
Descriptor:Hia (Adhesin)
Authors:Meng, G., Waksman, G.
Deposit date:2008-09-24
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Repetitive Architecture of the Haemophilus influenzae Hia Trimeric Autotransporter
J.Mol.Biol., 384, 2008
3EMI
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CRYSTAL STRUCTURE OF HIA 307-422 NON-ADHESIVE DOMAIN
Descriptor:Hia (Adhesin)
Authors:Meng, G., Waksman, G.
Deposit date:2008-09-24
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Repetitive Architecture of the Haemophilus influenzae Hia Trimeric Autotransporter
J.Mol.Biol., 384, 2008
3EMO
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CRYSTAL STRUCTURE OF TRANSMEMBRANE HIA 973-1098
Descriptor:Hia (Adhesin)
Authors:Meng, G., Waksman, G.
Deposit date:2008-09-24
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Repetitive Architecture of the Haemophilus influenzae Hia Trimeric Autotransporter
J.Mol.Biol., 384, 2008
3Q48
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA CUPB2 CHAPERONE
Descriptor:Chaperone CupB2
Authors:Cai, X., Wang, R., Filloux, A., Waksman, G., Meng, G.
Deposit date:2010-12-23
Release date:2011-02-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional characterization of Pseudomonas aeruginosa CupB chaperones
Plos One, 6, 2011
3RFZ
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CRYSTAL STRUCTURE OF THE FIMD USHER BOUND TO ITS COGNATE FIMC:FIMH SUBSTRATE
Descriptor:Type 1 fimbrial adhesin, Outer membrane usher protein, type 1 fimbrial synthesis, ...
Authors:Phan, G., Remaut, H., Lebedev, A., Geibel, S., Waksman, G.
Deposit date:2011-04-07
Release date:2011-06-01
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
5N8O
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CRYO EM STRUCTURE OF THE CONJUGATIVE RELAXASE TRAI OF THE F/R1 PLASMID SYSTEM
Descriptor:DNA helicase I, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')
Authors:Ilangovan, A., Zanetti, G., Waksman, G.
Deposit date:2017-02-23
Release date:2017-05-03
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation
Cell, 169, 2017
2BHM
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CRYSTAL STRUCTURE OF VIRB8 FROM BRUCELLA SUIS
Descriptor:TYPE IV SECRETION SYSTEM PROTEIN VIRB8
Authors:Bayliss, R., Baron, C., Waksman, G.
Deposit date:2005-01-14
Release date:2005-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Two Core Subunits of the Bacterial Type Iv Secretion System, Virb8 from Brucella Suis and Comb10 from Helicobacter Pylori
Proc.Natl.Acad.Sci.USA, 102, 2005