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2XTT
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BOVINE TRYPSIN IN COMPLEX WITH EVOLUTIONARY ENHANCED SCHISTOCERCA GREGARIA PROTEASE INHIBITOR 1 (SGPI-1-P02)
Descriptor:PROTEASE INHIBITOR SGPI-1, CATIONIC TRYPSIN, CALCIUM ION, ...
Authors:Wahlgren, W.Y., Pal, G., Kardos, J., Porrogi, P., Szenthe, B., Patthy, A., Graf, L., Katona, G.
Deposit date:2010-10-12
Release date:2010-11-10
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:The Catalytic Aspartate is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-Like Inhibitor: A Refined Mechanism of Serine Protease Action.
J.Biol.Chem., 286, 2011
4AM2
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BACTERIOFERRITIN FROM BLASTOCHLORIS VIRIDIS
Descriptor:BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, FE (III) ION
Authors:Wahlgren, W.Y., Omran, H., von Stetten, D., Royant, A., van der Post, S., Katona, G.
Deposit date:2012-03-07
Release date:2012-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Characterization of Bacterioferritin from Blastochloris Viridis.
Plos One, 7, 2012
4AM4
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BACTERIOFERRITIN FROM BLASTOCHLORIS VIRIDIS
Descriptor:BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, FE (III) ION
Authors:Wahlgren, W.Y., Omran, H., von Stetten, D., Royant, A., van der Post, S., Katona, G.
Deposit date:2012-03-07
Release date:2012-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural Characterization of Bacterioferritin from Blastochloris Viridis.
Plos One, 7, 2012
4AM5
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BACTERIOFERRITIN FROM BLASTOCHLORIS VIRIDIS
Descriptor:BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, FE (III) ION
Authors:Wahlgren, W.Y., Omran, H., von Stetten, D., Royant, A., van der Post, S., Katona, G.
Deposit date:2012-03-07
Release date:2012-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural Characterization of Bacterioferritin from Blastochloris Viridis.
Plos One, 7, 2012
5NV9
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SUBSTRATE-BOUND OUTWARD-OPEN STATE OF A NA+-COUPLED SIALIC ACID SYMPORTER REVEALS A NOVEL NA+-SITE
Descriptor:Putative sodium:solute symporter, SODIUM ION, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, ...
Authors:Wahlgren, W.Y., North, R.A., Dunevall, E., Paz, A., Goyal, P., Bisignano, P., Grabe, M., Dobson, R., Abramson, J., Ramaswamy, S., Friemann, R.
Deposit date:2017-05-03
Release date:2018-04-04
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.
Nat Commun, 9, 2018
5NVA
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SUBSTRATE-BOUND OUTWARD-OPEN STATE OF A NA+-COUPLED SIALIC ACID SYMPORTER REVEALS A NOVEL NA+-SITE
Descriptor:Putative sodium:solute symporter, SODIUM ION, 5-N-ACETYL-BETA-D-NEURAMINIC ACID
Authors:Wahlgren, W.Y., North, R.A., Dunevall, E., Goyal, P., Grabe, M., Dobson, R., Abramson, J., Ramaswamy, S., Friemann, R.
Deposit date:2017-05-03
Release date:2018-04-04
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.
Nat Commun, 9, 2018
2WJM
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LIPIDIC SPONGE PHASE CRYSTAL STRUCTURE OF THE PHOTOSYNTHETIC REACTION CENTRE FROM BLASTOCHLORIS VIRIDIS (LOW DOSE)
Descriptor:PHOTOSYNTHETIC REACTION CENTER CYTOCHROME C SUBUNIT, REACTION CENTER PROTEIN H CHAIN, REACTION CENTER PROTEIN L CHAIN, ...
Authors:Woehri, A.B., Wahlgren, W.Y., Malmerberg, E., Johansson, L.C., Neutze, R., Katona, G.
Deposit date:2009-05-27
Release date:2009-09-22
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Lipidic sponge phase crystal structure of a photosynthetic reaction center reveals lipids on the protein surface.
Biochemistry, 48, 2009
2WJN
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LIPIDIC SPONGE PHASE CRYSTAL STRUCTURE OF PHOTOSYNTHETIC REACTION CENTRE FROM BLASTOCHLORIS VIRIDIS (HIGH DOSE)
Descriptor:PHOTOSYNTHETIC REACTION CENTER CYTOCHROME C SUBUNIT, REACTION CENTER PROTEIN H CHAIN, REACTION CENTER PROTEIN L CHAIN, ...
Authors:Wohri, A.B., Wahlgren, W.Y., Malmerberg, E., Johansson, L.C., Neutze, R., Katona, G.
Deposit date:2009-05-27
Release date:2009-09-22
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Lipidic sponge phase crystal structure of a photosynthetic reaction center reveals lipids on the protein surface.
Biochemistry, 48, 2009
2XQQ
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE (AC-SRGTQTE).
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, SAC-ARG-GLY-THR-GLN-THR-GLU, ...
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-09-07
Release date:2011-05-04
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
Plos One, 6, 2011
3P8M
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE DIMERIZED BY LEUCINE ZIPPER
Descriptor:Dynein light chain 2, General control protein GCN4
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-10-14
Release date:2011-08-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
4AC5
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LIPIDIC SPONGE PHASE CRYSTAL STRUCTURE OF THE BL. VIRIDIS REACTION CENTRE SOLVED USING SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:PHOTOSYNTHETIC REACTION CENTER CYTOCHROME C SUBUNIT, REACTION CENTER PROTEIN H CHAIN, REACTION CENTER PROTEIN L CHAIN, ...
Authors:Johansson, L.C., Arnlund, D., White, T.A., Katona, G., DePonte, D.P., Weierstall, U., Doak, R.B., Shoeman, R.L., Lomb, L., Malmerberg, E., Davidsson, J., Nass, K., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M.J., Bostedt, C., Bozek, J.D., Caleman, C., Coffee, R., Coppola, N., Ekeberg, T., Epp, S.W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C.Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M.S., Kassemeyer, S., Kimmel, N., Kirian, R.A., Maia, F.R.N.C., Marchesini, S., Martin, A.V., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M.M., Sierra, R., Soltau, H., Starodub, D., Stellato, F., Stern, S., Struder, L., Timneanu, N., Ullrich, J., Wahlgren, W.Y., Wang, X., Weidenspointner, G., Wunderer, C., Fromme, P., Chapman, H.N., Spence, J.C.H., Neutze, R.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (8.2 Å)
Cite:Lipidic Phase Membrane Protein Serial Femtosecond Crystallography.
Nat.Methods, 9, 2012
4CAS
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SERIAL FEMTOSECOND CRYSTALLOGRAPHY STRUCTURE OF A PHOTOSYNTHETIC REACTION CENTER
Descriptor:PHOTOSYNTHETIC REACTION CENTER CYTOCHROME C SUBUNIT, REACTION CENTER PROTEIN L CHAIN, REACTION CENTER PROTEIN M CHAIN, ...
Authors:Johansson, L.C., Arnlund, D., Katona, G., White, T.A., Barty, A., DePonte, D.P., Shoeman, R.L., Wickstrand, C., Sharma, A., Williams, G.J., Aquila, A., Bogan, M.J., Caleman, C., Davidsson, J., Doak, R.B., Frank, M., Fromme, R., Galli, L., Grotjohann, I., Hunter, M.S., Kassemeyer, S., Kirian, R.A., Kupitz, C., Liang, M., Lomb, L., Malmerberg, E., Martin, A.V., Messerschmidt, M., Nass, K., Redecke, L., Seibert, M.M., Sjohamn, J., Steinbrener, J., Stellato, F., Wang, D., Wahlgren, W.Y., Weierstall, U., Westenhoff, S., Zatsepin, N.A., Boutet, S., Spence, J.C.H., Schlichting, I., Chapman, H.N., Fromme, P., Neutze, R.
Deposit date:2013-10-09
Release date:2013-12-25
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography.
Nat Commun, 4, 2013
4D07
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DYNLL2 DYNEIN LIGHT CHAIN BINDS TO AN EXTENDED, UNSTRUCTURED LINEAR MOTIF OF MYOSIN 5A TAIL
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, MYOSIN VA VARIANT, ...
Authors:Bodor, A., Radnai, L., Hetenyi, C., Rapali, P., Lang, A., Kover, K.E., Perczel, A., Wahlgren, W.Y., Katona, G., Nyitray, L.
Deposit date:2014-04-24
Release date:2014-10-22
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity.
Biochemistry, 53, 2014
5APC
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HEN EGG WHITE LYSOZYME ILLUMINATED WITH 0.4THZ RADIATION
Descriptor:LYSOZYME C, SODIUM ION
Authors:Lundholm, I., Rodilla, H., Wahlgren, W.Y., Duelli, A., Bourenkov, G., Vukusic, J., Friedman, R., Stake, J., Schneider, T., Katona, G.
Deposit date:2015-09-15
Release date:2016-01-13
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Terahertz Radiation Induces Non-Thermal Structural Changes Associated with Frohlich Condensation in a Protein Crystal
Struct.Dyn., 2, 2015
5APD
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HEN EGG WHITE LYSOZYME NOT ILLUMINATED WITH 0.4THZ RADIATION
Descriptor:LYSOZYME C, SODIUM ION
Authors:Lundholm, I., Rodilla, H., Wahlgren, W.Y., Duelli, A., Bourenkov, G., Vukusic, J., Friedman, R., Stake, J., Schneider, T., Katona, G.
Deposit date:2015-09-15
Release date:2016-01-13
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Terahertz Radiation Induces Non-Thermal Structural Changes Associated with Frohlich Condensation in a Protein Crystal
Struct.Dyn., 2, 2015
5APE
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HEN EGG WHITE LYSOZYME REFERENCE DATASET ODD FRAMES
Descriptor:LYSOZYME C, SODIUM ION
Authors:Lundholm, I., Rodilla, H., Wahlgren, W.Y., Duelli, A., Bourenkov, G., Vukusic, J., Friedman, R., Stake, J., Schneider, T., Katona, G.
Deposit date:2015-09-15
Release date:2016-01-13
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Terahertz Radiation Induces Non-Thermal Structural Changes Associated with Frohlich Condensation in a Protein Crystal
Struct.Dyn., 2, 2015
5APF
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HEN EGG WHITE LYSOZYME REFERENCE DATASET EVEN FRAMES
Descriptor:LYSOZYME C, SODIUM ION
Authors:Lundholm, I., Rodilla, H., Wahlgren, W.Y., Duelli, A., Bourenkov, G., Vukusic, J., Friedman, R., Stake, J., Schneider, T., Katona, G.
Deposit date:2015-09-15
Release date:2016-01-13
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Terahertz Radiation Induces Non-Thermal Structural Changes Associated with Frohlich Condensation in a Protein Crystal
Struct.Dyn., 2, 2015
5M7J
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BLASTOCHLORIS VIRIDIS PHOTOSYNTHETIC REACTION CENTER STRUCTURE USING BEST CRYSTAL APPROACH
Descriptor:Photosynthetic reaction center cytochrome c subunit, Reaction center protein L chain, Reaction center protein M chain, ...
Authors:Sharma, A.S., Johansson, L., Dunevall, E., Wahlgren, W.Y., Neutze, R., Katona, G.
Deposit date:2016-10-28
Release date:2017-02-08
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Asymmetry in serial femtosecond crystallography data.
Acta Crystallogr A Found Adv, 73, 2017
5M7K
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BLASTOCHLORIS VIRIDIS PHOTOSYNTHETIC REACTION CENTER - RC_VIR_XFEL
Descriptor:Photosynthetic reaction center cytochrome c subunit, Reaction center protein L chain, Reaction center protein M chain, ...
Authors:Sharma, A.S., Johansson, L., Dunevall, E., Wahlgren, W.Y., Neutze, R., Katona, G.
Deposit date:2016-10-28
Release date:2017-02-08
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Asymmetry in serial femtosecond crystallography data.
Acta Crystallogr A Found Adv, 73, 2017
5M7L
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BLASTOCHLORIS VIRIDIS PHOTOSYNTHETIC REACTION CENTER SYNCHROTRON STRUCTURE
Descriptor:Photosynthetic reaction center cytochrome c subunit, Reaction center protein L chain, Reaction center protein M chain, ...
Authors:Sharma, A.S., Johansson, L., Dunevall, E., Wahlgren, W.Y., Neutze, R., Katona, G.
Deposit date:2016-10-28
Release date:2017-02-08
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Asymmetry in serial femtosecond crystallography data.
Acta Crystallogr A Found Adv, 73, 2017
6F2U
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POTENT AND SELECTIVE ALDO-KETO REDUCTASE 1C3 (AKR1C3) INHIBITORS BASED ON THE BENZOISOXAZOLE MOIETY: APPLICATION OF A BIOISOSTERIC SCAFFOLD HOPPING APPROACH TO FLUFENAMIC ACID
Descriptor:Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-[(4-methoxyphenyl)methyl]-5-oxidanyl-~{N}-[3-(trifluoromethyl)phenyl]-1,2,3-triazole-4-carboxamide
Authors:Goyal, P., Wahlgren, W.Y., Friemann, R.
Deposit date:2017-11-27
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid.
Eur J Med Chem, 150, 2018
6F78
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POTENT AND SELECTIVE ALDO-KETO REDUCTASE 1C3 (AKR1C3) INHIBITORS BASED ON THE BENZOISOXAZOLE MOIETY: APPLICATION OF A BIOISOSTERIC SCAFFOLD HOPPING APPROACH TO FLUFENAMIC ACID
Descriptor:Aldo-keto reductase family 1 member C3, 4-[[3,5-bis(trifluoromethyl)phenyl]amino]-1,2-benzoxazol-3-one, CHLORIDE ION, ...
Authors:Goyal, P., Wahlgren, W.Y., Friemann, R.
Deposit date:2017-12-07
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid.
Eur J Med Chem, 150, 2018
6GXK
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CRYSTAL STRUCTURE OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) COMPLEXED WITH INHIBITOR.
Descriptor:Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-[[1-(4-chlorophenyl)carbonyl-5-methoxy-2-methyl-indol-3-yl]methyl]-1,2,5-oxadiazol-3-one, ...
Authors:Goyal, P., Wahlgren, W.Y., Friemann, R.
Deposit date:2018-06-27
Release date:2019-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Effective Application of a Bioisosteric Scaffold Hopping Approach to the Indomethacine modulation: design of new and selective Aldo-Keto Reductase 1C3 (AKR1C3) inhibitors
To Be Published