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1HKG
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STRUCTURAL DYNAMICS OF YEAST HEXOKINASE DURING CATALYSIS
Descriptor:HEXOKINASE A
Authors:Bennett Jr., W.S., Steitz, T.A.
Deposit date:1980-12-22
Release date:1981-02-26
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural dynamics of yeast hexokinase during catalysis.
Philos.Trans.R.Soc.London,Ser.B, 293, 1981
1CMA
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MET REPRESSOR/DNA COMPLEX + S-ADENOSYL-METHIONINE
Descriptor:DNA (5'-D(*TP*TP*AP*GP*AP*CP*GP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*CP*GP*TP*CP*TP*A)-3'), PROTEIN (MET REPRESSOR), ...
Authors:Somers, W.S., Phillips, S.E.V.
Deposit date:1992-08-24
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the met repressor-operator complex at 2.8 A resolution reveals DNA recognition by beta-strands.
Nature, 359, 1992
1DII
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CRYSTAL STRUCTURE OF P-CRESOL METHYLHYDROXYLASE AT 2.5 A RESOLUTION
Descriptor:P-CRESOL METHYLHYDROXYLASE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Cunane, L.M., Chen, Z.W., Shamala, N., Mathews, F.S., Cronin, C.N., McIntire, W.S.
Deposit date:1999-11-29
Release date:1999-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism.
J.Mol.Biol., 295, 2000
1DIQ
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CRYSTAL STRUCTURE OF P-CRESOL METHYLHYDROXYLASE WITH SUBSTRATE BOUND
Descriptor:P-CRESOL METHYLHYDROXYLASE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Cunane, L.M., Chen, Z.W., Shamala, N., Mathews, F.S., Cronin, C.S., McIntire, W.S.
Deposit date:1999-11-29
Release date:1999-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism.
J.Mol.Biol., 295, 2000
1HLA
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STRUCTURE OF THE HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN, HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2) (ALPHA CHAIN), BETA 2-MICROGLOBULIN
Authors:Bjorkman, P.J., Saper, M.A., Samraoui, B., Bennett, W.S., Strominger, J.L., Wiley, D.C.
Deposit date:1987-10-15
Release date:1988-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the human class I histocompatibility antigen, HLA-A2.
Nature, 329, 1987
1I7E
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C-TERMINAL DOMAIN OF MOUSE BRAIN TUBBY PROTEIN BOUND TO PHOSPHATIDYLINOSITOL 4,5-BIS-PHOSPHATE
Descriptor:TUBBY PROTEIN, L-ALPHA-GLYCEROPHOSPHO-D-MYO-INOSITOL-4,5-BIS-PHOSPHATE
Authors:Santagata, S., Boggon, T.J., Baird, C.L., Shan, W.S., Shapiro, L.
Deposit date:2001-03-08
Release date:2001-06-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:G-protein signaling through tubby proteins.
Science, 292, 2001
1SQ0
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE WILD-TYPE VON WILLEBRAND FACTOR A1 DOMAIN AND GLYCOPROTEIN IB ALPHA AT 2.6 ANGSTROM RESOLUTION
Descriptor:Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II], Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin]
Authors:Dumas, J.J., Kumar, R., McDonagh, T., Sullivan, F., Stahl, M.L., Somers, W.S., Mosyak, L.
Deposit date:2004-03-17
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
1WVE
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P-CRESOL METHYLHYDROXYLASE: ALTERATION OF THE STRUCTURE OF THE FLAVOPROTEIN SUBUNIT UPON ITS BINDING TO THE CYTOCHROME SUBUNIT
Descriptor:4-cresol dehydrogenase [hydroxylating] flavoprotein subunit, 4-cresol dehydrogenase [hydroxylating] cytochrome c subunit, CHLORIDE ION, ...
Authors:Cunane, L.M., Chen, Z.-W., McIntire, W.S., Mathews, F.S.
Deposit date:2004-12-15
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:p-Cresol Methylhydroxylase: Alteration of the Structure of the Flavoprotein Subunit upon Its Binding to the Cytochrome Subunit
Biochemistry, 44, 2005
1WVF
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P-CRESOL METHYLHYDROXYLASE: ALTERATION OF THE STRUCTURE OF THE FLAVOPROTEIN SUBUNIT UPON ITS BINDING TO THE CYTOCHROME SUBUNIT
Descriptor:4-cresol dehydrogenase [hydroxylating] flavoprotein subunit, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Cunane, L.M., Chen, Z.-W., McIntire, W.S., Mathews, F.S.
Deposit date:2004-12-15
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:p-Cresol Methylhydroxylase: Alteration of the Structure of the Flavoprotein Subunit upon Its Binding to the Cytochrome Subunit
Biochemistry, 44, 2005
5JN8
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CRYSTAL STRUCTURE FOR THE COMPLEX OF HUMAN CARBONIC ANHYDRASE IV AND ACETAZOLAMIDE
Descriptor:Carbonic anhydrase 4, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ZINC ION, ...
Authors:Chen, Z., Waheed, A., Di Cera, E., Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
5JN9
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CRYSTAL STRUCTURE FOR THE COMPLEX OF HUMAN CARBONIC ANHYDRASE IV AND ETHOXYZOLAMIDE
Descriptor:Carbonic anhydrase 4, ZINC ION, 6-ethoxy-1,3-benzothiazole-2-sulfonamide, ...
Authors:Chen, Z., Waheed, A., Di Cera, E., Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
5JNA
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CRYSTAL STRUCTURE FOR THE COMPLEX OF HUMAN CARBONIC ANHYDRASE IV AND TOPIRAMATE
Descriptor:Carbonic anhydrase 4, ZINC ION, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate, ...
Authors:Chen, Z., Waheed, A., Di Cera, E., Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
5JNC
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CRYSTAL STRUCTURE FOR THE COMPLEX OF HUMAN CARBONIC ANHYDRASE IV AND 4-AMINOMETHYLBENZENE SULFONAMIDE
Descriptor:Carbonic anhydrase 4, ZINC ION, 4-(aminomethyl)benzene-1-sulfonamide, ...
Authors:Chen, Z., Waheed, A., Di Cera, E., Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
5KU6
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CRYSTAL STRUCTURE FOR THE COMPLEX OF HUMAN CARBONIC ANHYDRASE IV AND METHAZOLAMIDE
Descriptor:Carbonic anhydrase 4, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION, ...
Authors:Chen, Z., Waheed, A., Di Cera, E., Sly, W.S.
Deposit date:2016-07-12
Release date:2017-07-26
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
1AEI
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CRYSTAL STRUCTURE OF THE ANNEXIN XII HEXAMER
Descriptor:ANNEXIN XII, CALCIUM ION
Authors:Luecke, H., Chang, B.T., Mailliard, W.S., Schlaepfer, D.D., Haigler, H.T.
Deposit date:1995-09-23
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
Nature, 378, 1995
1B7E
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TRANSPOSASE INHIBITOR
Descriptor:PROTEIN (TRANSPOSASE INHIBITOR PROTEIN FROM TN5), 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride
Authors:Davies, D.R., Braam, L.M., Reznikoff, W.S., Rayment, I.
Deposit date:1999-01-22
Release date:1999-04-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9A resolution.
J.Biol.Chem., 274, 1999
1BSV
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GDP-FUCOSE SYNTHETASE FROM ESCHERICHIA COLI COMPLEX WITH NADPH
Descriptor:PROTEIN (GDP-FUCOSE SYNTHETASE), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Somers, W.S., Stahl, M.L., Sullivan, F.X.
Deposit date:1998-08-31
Release date:1999-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site.
Structure, 6, 1998
1CJY
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HUMAN CYTOSOLIC PHOSPHOLIPASE A2
Descriptor:PROTEIN (CYTOSOLIC PHOSPHOLIPASE A2), CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Dessen, A., Tang, J., Schmidt, H., Stahl, M., Clark, J.D., Seehra, J., Somers, W.S.
Deposit date:1999-04-20
Release date:2000-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism.
Cell(Cambridge,Mass.), 97, 1999
1CMC
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THREE DIMENSIONAL CRYSTAL STRUCTURES OF E. COLI MET REPRESSOR WITH AND WITHOUT COREPRESSOR
Descriptor:MET REPRESSOR, MAGNESIUM ION, S-ADENOSYLMETHIONINE
Authors:Somers, W.S., Phillips, S.E.V.
Deposit date:1992-08-28
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional crystal structures of Escherichia coli met repressor with and without corepressor.
Nature, 341, 1989
1DB3
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E.COLI GDP-MANNOSE 4,6-DEHYDRATASE
Descriptor:GDP-MANNOSE 4,6-DEHYDRATASE
Authors:Somoza, J.R., Menon, S., Somers, W.S., Sullivan, F.X.
Deposit date:1999-11-02
Release date:1999-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme's catalytic mechanism and regulation by GDP-fucose.
Structure Fold.Des., 8, 2000
1DQE
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BOMBYX MORI PHEROMONE BINDING PROTEIN
Descriptor:PHEROMONE-BINDING PROTEIN, HEXADECA-10,12-DIEN-1-OL
Authors:Sandler, B.H., Nikonova, L., Leal, W.S., Clardy, J.
Deposit date:2000-01-04
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sexual attraction in the silkworm moth: structure of the pheromone-binding-protein-bombykol complex.
Chem.Biol., 7, 2000
1F42
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THE P40 DOMAIN OF HUMAN INTERLEUKIN-12
Descriptor:INTERLEUKIN-12 BETA CHAIN, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Yoon, C., Johnston, S.C., Tang, J., Tobin, J.F., Somers, W.S.
Deposit date:2000-06-07
Release date:2001-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.
EMBO J., 19, 2000
1F45
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HUMAN INTERLEUKIN-12
Descriptor:INTERLEUKIN-12 BETA CHAIN, INTERLEUKIN-12 ALPHA CHAIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Yoon, C., Johnston, S.C., Tang, J., Tobin, J.F., Somers, W.S.
Deposit date:2000-06-07
Release date:2001-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.
EMBO J., 19, 2000
1F46
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THE BACTERIAL CELL-DIVISION PROTEIN ZIPA AND ITS INTERACTION WITH AN FTSZ FRAGMENT REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor:CELL DIVISION PROTEIN ZIPA
Authors:Mosyak, L., Zhang, Y., Glasfeld, E., Stahl, M., Somers, W.S.
Deposit date:2000-06-07
Release date:2001-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography.
EMBO J., 19, 2000
1F47
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THE BACTERIAL CELL-DIVISION PROTEIN ZIPA AND ITS INTERACTION WITH AN FTSZ FRAGMENT REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor:CELL DIVISION PROTEIN ZIPA, CELL DIVISION PROTEIN FTSZ
Authors:Mosyak, L., Zhang, Y., Glasfeld, E., Stahl, M., Somers, W.S.
Deposit date:2000-06-07
Release date:2001-06-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography.
EMBO J., 19, 2000