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1YJ7
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CRYSTAL STRUCTURE OF ENTEROPATHOGENIC E.COLI (EPEC) TYPE III SECRETION SYSTEM PROTEIN ESCJ
Descriptor:escJ, PHOSPHATE ION, GLYCEROL
Authors:Yip, C.K., Kimbrough, T.G., Felise, H.B., Vuckovic, M., Thomas, N.A., Pfuetzner, R.A., Frey, E.A., Finlay, B.B., Miller, S.I., Strynadka, N.C.J.
Deposit date:2005-01-13
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of the molecular platform for type III secretion system assembly.
Nature, 435, 2005
2OBL
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STRUCTURAL AND BIOCHEMICAL ANALYSIS OF A PROTOTYPICAL ATPASE FROM THE TYPE III SECRETION SYSTEM OF PATHOGENIC BACTERIA
Descriptor:EscN, CALCIUM ION, ACETATE ION, ...
Authors:Zarivach, R., Vuckovic, M., Deng, W., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2006-12-19
Release date:2007-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of a prototypical ATPase from the type III secretion system.
Nat.Struct.Mol.Biol., 14, 2007
2OBM
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STRUCTURAL AND BIOCHEMICAL ANALYSIS OF A PROTOTYPICAL ATPASE FROM THE TYPE III SECRETION SYSTEM OF PATHOGENIC BACTERIA
Descriptor:EscN, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Zarivach, R., Vuckovic, M., Deng, W., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2006-12-19
Release date:2007-01-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural analysis of a prototypical ATPase from the type III secretion system.
Nat.Struct.Mol.Biol., 14, 2007
2X49
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF INVA
Descriptor:INVASION PROTEIN INVA, MERCURY (II) ION, CALCIUM ION, ...
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2010-01-28
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of the C-Terminal Domain of the Salmonella Type III Secretion System Export Apparatus Protein Inva.
Protein Sci., 19, 2010
2X4A
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF INVA
Descriptor:INVASION PROTEIN INVA, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, PHOSPHATE ION
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2010-01-28
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal Structure of the C-Terminal Domain of the Salmonella Type III Secretion System Export Apparatus Protein Inva.
Protein Sci., 19, 2010
3BZL
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CRYSTAL STRUCTURAL OF NATIVE ESCU C-TERMINAL DOMAIN
Descriptor:EscU, SODIUM ION, FORMIC ACID
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZO
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CRYSTAL STRUCTURAL OF NATIVE ESCU C-TERMINAL DOMAIN
Descriptor:EscU, SULFATE ION
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZP
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CRYSTAL STRUCTURAL OF THE MUTATED N262A ESCU C-TERMINAL DOMAIN
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZR
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CRYSTAL STRUCTURE OF ESCU C-TERMINAL DOMAIN WITH N262D MUTATION, SPACE GROUP P 41 21 2
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.646 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZS
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CRYSTAL STRUCTURE OF ESCU C-TERMINAL DOMAIN WITH N262D MUTATION, SPACE GROUP P 21 21 21
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZT
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CRYSTAL STRUCTURAL OF THE MUTATED P263A ESCU C-TERMINAL DOMAIN
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZV
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CRYSTAL STRUCTURAL OF THE MUTATED T264A ESCU C-TERMINAL DOMAIN
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZX
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CRYSTAL STRUCTURE OF THE MUTATED H265A ESCU C-TERMINAL DOMAIN
Descriptor:EscU, SULFATE ION
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZY
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CRYSTAL STRUCTURE OF THE MUTATED Y316D ESCU C-TERMINAL DOMAIN
Descriptor:EscU, SULFATE ION
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3BZZ
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CRYSTAL STRUCTURAL OF THE MUTATED R313T ESCU/SPAS C-TERMINAL DOMAIN
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.407 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3C00
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CRYSTAL STRUCTURAL OF THE MUTATED G247T ESCU/SPAS C-TERMINAL DOMAIN
Descriptor:EscU
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3C01
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CRYSTAL STRUCTURAL OF NATIVE SPAS C-TERMINAL DOMAIN
Descriptor:Surface presentation of antigens protein spaS, SULFATE ION, CYSTEINE, ...
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3C03
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CRYSTAL STRUCTURE OF THE ESCU C-TERMINAL DOMAIN WITH P263A MUTATION,SPACE GROUP P 1 21 1
Descriptor:EscU, PROLINE
Authors:Zarivach, R., Deng, W., Vuckovic, M., Felise, H.B., Nguyen, H.V., Miller, S.I., Finlay, B.B., Strynadka, N.C.J.
Deposit date:2008-01-18
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3ECQ
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ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE: SEMET STRUCTURE
Descriptor:Endo-alpha-N-acetylgalactosaminidase, CALCIUM ION, SODIUM ION, ...
Authors:Caines, M.E.C., Zhu, H., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2008-09-01
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structural basis for T-antigen hydrolysis by Streptococcus pneumoniae: a target for structure-based vaccine design.
J.Biol.Chem., 283, 2008
3T05
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CRYSTAL STRUCTURE OF S. AUREUS PYRUVATE KINASE
Descriptor:Pyruvate kinase, PHOSPHATE ION
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3T07
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CRYSTAL STRUCTURE OF S. AUREUS PYRUVATE KINASE IN COMPLEX WITH A NATURALLY OCCURRING BIS-INDOLE ALKALOID
Descriptor:Pyruvate kinase, PHOSPHATE ION, (3S,5R)-3,5-bis(6-bromo-1H-indol-3-yl)piperazin-2-one
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
4G2S
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CRYSTAL STRUCTURE OF A SALMONELLA TYPE III SECRETION SYSTEM PROTEIN
Descriptor:Protein prgH, CALCIUM ION
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2012-07-12
Release date:2013-05-15
Method:X-RAY DIFFRACTION (1.858 Å)
Cite:A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly.
Plos Pathog., 9, 2013
5FA7
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CTX-M-15 IN COMPLEX WITH FPI-1523
Descriptor:Beta-lactamase, [[(3~{R},6~{S})-6-(acetamidocarbamoyl)-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate
Authors:King, A.M., King, D.T., French, S., Brouillette, E., Asli, A., Alexander, A.N., Vuckovic, M., Maiti, S.N., Parr, T.R., Brown, E.D., Malouin, F., Strynadka, N.C.J., Wright, G.D.
Deposit date:2015-12-11
Release date:2016-01-20
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins.
Acs Chem.Biol., 11, 2016
5FAO
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CTX-M-15 IN COMPLEX WITH FPI-1465
Descriptor:Beta-lactamase, [[(3~{R},6~{S})-1-methanoyl-6-[[(3~{S})-pyrrolidin-3-yl]oxycarbamoyl]piperidin-3-yl]amino] hydrogen sulfate
Authors:King, A.M., King, D.T., French, S., Brouillette, E., Asli, A., Alexander, A.N., Vuckovic, M., Maiti, S.N., Parr, T.R., Brown, E.D., Malouin, F., Strynadka, N.C.J., Wright, G.D.
Deposit date:2015-12-11
Release date:2016-02-17
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins.
Acs Chem.Biol., 11, 2016
5FAP
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CTX-M-15 IN COMPLEX WITH FPI-1602
Descriptor:Beta-lactamase, [[(3~{R},6~{S})-6-[(azetidin-3-ylcarbonylamino)carbamoyl]-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate
Authors:King, A.M., King, D.T., French, S., Brouillette, E., Asli, A., Alexander, A.N., Vuckovic, M., Maiti, S.N., Parr, T.R., Brown, E.D., Malouin, F., Strynadka, N.C.J., Wright, G.D.
Deposit date:2015-12-11
Release date:2016-01-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins.
Acs Chem.Biol., 11, 2016
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